Publications of Soni Savai Pullamsetti

Karger, A.; Mansouri, S.; Leisegang , M. S.; Weigert, A.; Guenther, S.; Kuenne, C.; Wittig , I.; Zukunft , S.; Klatt , S.; Aliraj , B. et al.; Klotz V , L.; Winter , H.; Mahavadi, P.; Fleming , I.; Ruppert , C.; Witte , B.; Alkoudmani , I.; Gattenloehner, S.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. EMBO JOURNAL (2023)

Zheng, X.; Sarode, P.; Weigert , A.; Turkowski, K.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Winter , H.; Stenzinger, A.; Reu, S. et al.; Grimminger, F.; Stiewe, T.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. CANCER RESEARCH 83 (14), pp. 2345 - 2357 (2023)

Goncharova , E. A.; V. Kudryashova , T.; Pullamsetti, S. S.: Too hot? Too cold? Wnt signalling in pulmonary arterial hypertension: can we treat it "just right"? EUROPEAN RESPIRATORY JOURNAL 61 (6), 2300504 (2023)

Goldschmid, H.; Kluck, K.; Ball, M.; Kirchner, M.; Allgaeuer, M.; Winter, H.; Herth, F.; Heussel, C.-P.; Pullamsetti, S. S.; Savai, R. et al.; Yong, T. T. K.; Schirmacher, P.; Peters, S.; Thomas, M.; Christopoulos, P.; Budczies, J.; Stenzinger, A.; Kazdal, D.: Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naive lung adenocarcinomas. LUNG CANCER 180, 107212 (2023)

Nayakanti, S. R.; Friedrich, A.; Sarode, P.; Jafari, L.; Maroli, G.; Boehm, M.; Bourgeois, A.; Grobs, Y.; Khassafi, F.; Kuenne, C. et al.; Guenther, S.; Dabral, S.; Wilhelm, J.; Weiss, A.; Wietelmann, A.; Kojonazarov, B.; Janssen, W.; Looso, M.; de Man, F.; Provencher, S.; Tello, K.; Seeger, W.; Bonnet, S.; Savai, R.; Schermuly, R.; Pullamsetti, S. S.: Targeting Wnt-ss-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling. CIRCULATION RESEARCH 132 (11), pp. 1468 - 1485 (2023)

Selle, J.; Bohl, K.; Hoepker, K.; Wilke, R.; Dinger, K.; Kasper, P.; Abend, B.; Schermer, B.; Mueller, R.-U.; Kurschat, C. et al.; Nuesken, K.-D.; Nuesken, E.; Meyer, D.; Savai Pullamsetti, S.; Schumacher, B.; Doetsch, J.; Alcazar, M. A. A.: Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24 (3), 2508 (2023)

Boos, F.; Oo, J. A.; Warwick, T.; Guenther, S.; Ponce, J. I.; Lopez, M.; Rafii, D.; Buchmann, G.; Pham, M. D.; Msheik, Z. S. et al.; Li, T.; Seredinski, S.; Haydar, S.; Kashefiolasl, S.; Plate, K. H.; Behr, R.; Mietsch, M.; Krishnan, J.; Pullamsetti, S. S.; Bibli, S.-I.; Hinkel, R.; Baker, A. H.; Boon, R. A.; Schulz, M. H.; Wittig, I.; Miller Jr., F. J.; Brandes, R. P.; Leisegang, M. S.: The endothelial-enriched lncRNA LINC00607 mediates angiogenic function. BASIC RESEARCH IN CARDIOLOGY 118 (1), 5 (2023)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Medrano-Garcia, S.; Morales-Cano, D.; Barreira, B.; Vera-Zambrano, A.; Kumar, R.; Kosanovic, D.; Schermuly, R. T.; Graham, B. B.; Perez-Vizcaino, F.; Mathie, A. et al.; Savai, R.; Pullamseti, S.; Butrous, G.; Fernandez-Malave, E.; Cogolludo, A.: HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape. CELLS 11 (15), 2414 (2022)

Selle, J.; Dinger, K.; Jentgen, V.; Zanetti, D.; Will, J.; Georgomanolis, T.; Vohlen, C.; Wilke, R.; Kojonazarov, B.; Klymenko, O. et al.; Mohr, J.; Koningsbruggen-Rietschel, S. v.; Rhodes, C. J.; Ulrich, A.; Hirani, D.; Nestler, T.; Odenthal, M.; Mahabir, E.; Nayakanti, S.; Dabral, S.; Wunderlich, T.; Priest, J.; Seeger, W.; Doetsch, J.; Pullamsetti, S. S.; Alcazar, M. A. A.: Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. NATURE COMMUNICATIONS 13 (1), 4352 (2022)

Kuhnert, S.; Mansouri, S.; Rieger, M. A.; Savai, R.; Avci, E.; Diaz-Pina, G.; Padmasekar, M.; Looso, M.; Hadzic, S.; Acker, T. et al.; Klatt, S.; Wilhelm, J.; Fleming, I.; Sommer, N.; Weissmann, N.; Vogelmeier, C.; Bals, R.; Zeiher, A.; Dimmeler, S.; Seeger, W.; Pullamsetti, S. S.: Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD. CELLS 11 (13), 2121 (2022)

Chelladurai, P.; Kuenne, C.; Bourgeois, A.; Guenther, S.; Valasarajan, C.; Cherian V, A.; Rottier, R. J.; Romanet, C.; Weigert, A.; Boucherat, O. et al.; Eichstaedt, C. A.; Ruppert, C.; Guenther, A.; Braun, T.; Looso, M.; Savai, R.; Seeger, W.; Bauer, U.-M.; Bonnet, S.; Pullamsetti, S. S.: Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension. SCIENCE TRANSLATIONAL MEDICINE 14 (648), eabe5407 (2022)

Kudryashova V, T.; Dabral, S.; Nayakanti, S.; Ray, A.; Goncharov, D. A.; Avolio, T.; Shen, Y.; Rode, A.; Pena, A.; Jiang, L. et al.; Lin, D.; Baust, J.; Bachman, T. N.; Graumann, J.; Ruppert, C.; Guenther, A.; Schmoranzer, M.; Grobs, Y.; Lemay, S. E.; Tremblay, E.; Breuils-Bonnet, S.; Boucherat, O.; Mora, A. L.; DeLisser, H.; Zhao, J.; Zhao, Y.; Bonnet, S.; Seeger, W.; Pullamsetti, S. S.; Goncharova, E. A.: Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival. CIRCULATION RESEARCH 130 (5), pp. 760 - 778 (2022)

Olesch, C.; Brunn, D.; Aktay-Cetin, O.; Sirait-Fischer, E.; Pullamsetti, S. S.; Grimminger, F.; Seeger, W.; Bruene, B.; Weigert, A.; Savai, R.: Picturing of the Lung Tumor Cellular Composition by Multispectral Flow Cytometry. FRONTIERS IN IMMUNOLOGY 13, 827719 (2022)

Avci, E.; Sarvari, P.; Savai, R.; Seeger, W.; Pullamsetti, S. S.: Epigenetic Mechanisms in Parenchymal Lung Diseases: Bystanders or Therapeutic Targets? INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (1), 546 (2022)

Rajpoot, S.; Solanki, K.; Kumar, A.; Zhang, K. Y. J.; Pullamsetti, S. S.; Savai, R.; Faisal, S. M.; Pan, Q.; Baig, M. S.: In-Silico Design of a Novel Tridecapeptide Targeting Spike Protein of SARS-CoV-2 Variants of Concern. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS 28 (1), 28 (2021)

Halawa, S.; Pullamsetti, S. S.; Bangham, C. R. M.; Stenmark, K. R.; Dorfmuller, P.; Frid, M. G.; Butrous, G.; Morrell, N. W.; de Jesus Perez, V. A.; Stuart, D. I. et al.; O'Gallagher, K.; Shah, A. M.; Aguib, Y.; Yacoub, M. H.: Potential long-term effects of SARS-CoV-2 infection on the pulmonary vasculature: a global perspective. NATURE REVIEWS CARDIOLOGY (2021)

Berghausen, E. M.; Janssen, W.; Vantler, M.; Gnatzy-Feik, L. L.; Krause, M.; Behringer, A.; Joseph, C.; Zierden, M.; ten Freyhaus, H.; Klinke, A. et al.; Baldus, S.; Alcazar, M. A.; Savai, R.; Pullamsetti, S. S.; Wong, D. W. L.; Boor, P.; Zhao, J. J.; Schermuly, R. T.; Rosenkranz, S.: Disrupted PI3K subunit p110 alpha signaling protects against pulmonary hypertension and reverses established disease in rodents. JOURNAL OF CLINICAL INVESTIGATION 131 (19), e136939 (2021)

Qi, H.; Liu, H.; Pullamsetti, S. S.; Gunther, S.; Kuenne, C.; Atzberger, A.; Sommer, N.; Hadzic, S.; Gunther, A.; Weissmann, N. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Epigenetic Regulation by Suv4-20h1 in Cardiopulmonary Progenitor Cells Is Required to Prevent Pulmonary Hypertension and Chronic Obstructive Pulmonary Disease. CIRCULATION 144 (13), pp. 1042 - 1058 (2021)