Max Planck Institute for Heart and Lung Research - W. G. Kerckhoff Institute
MRI: Further selected projects
MRI may be used to quantitatively measure lung tumor burden and to follow up e.g. tumor growth. Images of a transgenic mouse model of hyperproliferation in the lung show clearly the replacement of the lung parenchyma Fig. 5.
Fat, muscle, tissue-free fluids, and bones generate different signals in response to various radio frequency pulses at distinct magnetic fields, due to their different relaxation properties. We perform MRI studies on mouse using T1-weighted multi-slice-multi-echo (MSME) pulse sequences and analyze the volume of muscle and fat in a well defined and comparable area of the mouse Fig. 6.
For studying disease pattern of stroke patients, we use a rat animal model with induction of focal cerebral ischemia and follow-up by MRI, Fig.7.