Scientific Publications

Neogi, U.; Ambikan, A. T.; Turkowski, K.; Schneider, M. A.; Beutgen, V. M.; Graumann, J.; Winter, H.; Bartkuhn, M.; Seeger, W.; Pullamsetti, S. S. et al.; Savai, R.: Plasma proteomic profiling and molecular clustering reveal immune-defined prognostic subtypes in lung adenocarcinoma. INTERNATIONAL JOURNAL OF CANCER (2025)

Roquid, K. A.; Vucetic, A.; Dyukova, E.; Hanssen , M. J.; Cho, H.; Bonnavion, R.; Mattonet, K.; Looso, M.; Sanda, M.; Strilic, B. et al.; Offermanns, S.: Lung endothelial PEAR1 induces tumor cell dormancy. MOLECULAR CANCER 24 (1), 278 (2025)

Yilian, W.; Dierickx, P.: Circadian transcriptional repressors REV-ERB α/β and E4BP4 regulate cardiac function. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 208 (2025)

Liu, X.; Lin, B.; Li, P.; Cai, Z.; Cao, W.; Yang, W.; Zeng, J.; Li, L.; Zhou, Y.; Huang, D. et al.; Stainier, D. Y. R.; Ran, P.; Yin, W.: Interplay of ECM organization, ROCK signaling, and cell polarity drives mesothelium formation and lung growth. NATURE COMMUNICATIONS 16 (1), 9610 (2025)

Alessio, C.; Pes, K.; Tarasco, M.; Rosa, J. T.; Poudel, S.; Pereira, H. G.; Louro, B.; Cancela, M. L.; Laize, V.; Gavaia, P. J.: Immunomodulatory inhibition of osteoclastogenesis by a marine microalgal ethanol fraction targeting T-cells, antigen presentation, and macrophage fate. FRONTIERS IN IMMUNOLOGY 16, 1655321 (2025)

Goody, P. R.; Christmann, D.; Goody, D.; Hildebrand, S.; Billig, H.; Nehl, D.; Chennupati, R.; Gladka, M.; Wilhelm-Jungling, K.; Uchida, S. et al.; Iris-Bibli, S.; Moore, J. B.; Hamdani, N.; Paneni, F.; Pullamsetti, S. S.; Zimmer, S.; Jansen, F.; Bakhtiary, F.; Aikawa, E.; Pfeifer, A.; Nickenig, G.; Hosen, M. R.: Calcific aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk. BASIC RESEARCH IN CARDIOLOGY 120 (5), pp. 991 - 1010 (2025)

Mahmoud, W.; Perniss, A.; Poharkar, K.; Keshavarz, M.; Gartner, U.; Oberwinkler, J.; Schutz, B.; Worzfeld, T.; Offermanns, S.; Kummer, W.: Differential expression of villin and advillin by neuroendocrine and tuft cells in the murine lower airways. CELL AND TISSUE RESEARCH 402 (1), pp. 1 - 20 (2025)

Georgieva, A. M.; Sreenivasan, K.; Ding, D.; Villeneuve, C.; Wickstrom, S. A.; Gunther, S.; Kuenne, C.; Gartner, U.; Guo, X.; Zhou, Y. et al.; Yuan, X.; Braun, T.: Regulation of NSL by TAF4A is critical for genome stability and quiescence of muscle stem cells. NATURE COMMUNICATIONS 16 (1), 8726 (2025)

Yin, Q.; Christelle, L.; Boettger, T.; Braun, T.: Enlargement of the muscle stem cell pool in linc-MYH-deficient mice does not prevent sarcopenia during aging. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 13, 1667437 (2025)

Mansouri, S.; Karger, A.; Ruppert, C.; Schneider, M. A.; Weigert, A.; Nandigama, R.; Aliraj, B.; Strotmann, L.; Cherian, A. V.; Pruefer, D. et al.; Dorfmuller, P.; Fink, L.; Alkoudmani, I.; Gattenlohner, S.; Eul, B.; Althoff, A.; Kleine, P.; Winter, H.; Guenther, A.; Ghofrani, H.-A.; Pullamsetti, S. S.; Grimminger, F.; Seeger, W.; Savai, R.: Living human lung slices for ex vivo modelling of lung cancer. JCI INSIGHT 10 (17), e190703 (2025)

Wang, T.; Bonnavion, R.; Piesker, J.; Guenther, S.; Wettschureck, N.: GPRC5B preserves a mature j3 cell state in obesity by controlling MafA expression. JCI INSIGHT 10 (20), e194115 (2025)

Langschied, F.; Leisegang, M. S.; Guenther, S.; Hahner, F.; Brandes, R. P.; Ebersberger, I.: Loss of multiple micro-RNAs uncovers multi-level restructuring of gene regulation in rodents. BMC GENOMICS 26 (1), 800 (2025)

Majumdar, S.; Bammidi, L. S.; Naik, H. C.; Manhas, A.; Baro, R.; Kalita, A.; Naskar, A. J.; Nidharshan, S.; Bariha, G. S.; Notani, D. et al.; Gayen, S.: Xist upstream deletion leads to dysregulation of Xist and autosomal gene expression. GENOME RESEARCH 35 (9), pp. 1992 - 2010 (2025)

Jan, D.; Brenton, B.; Bentsen, M.; Kuenne, C.; Looso, M.: PEAKQC: periodicity evaluation in single-cell ATAC-seq data for quality assessment. BRIEFINGS IN BIOINFORMATICS 26 (5), bbaf465 (2025)

Franck, L.; Hahnefeld, L.; Valek, L.; Klatt-Schreiner, K.; Wilken-Schmitz, A.; Alnouri, M. W.; Trautmann, S.; Weyer, M.-P.; Thomas, D.; Gurke, R. et al.; Offermanns, S.; Geisslinger, G.; Tegeder, I.: Elevated hexosylceramides in Parkinson's disease cause gene upregulations in neurons mimicking responses to pathogens. NPJ PARKINSONS DISEASE 11 (1), 268 (2025)

Eichhorn, M. E.; Niedermaier, B.; Charoentong, P.; Klotz V, L.; Baum, P.; Griffo, R.; Allgaeuer, M.; Stenzinger, A.; Bischoff, H.; Schneider, M. A. et al.; Christopoulos, P.; Haberkorn, U.; Heussel, C.-P.; Savai, R.; Roberti, M. P.; Zoernig, I.; Jaeger, D.; Herth, F.; Thomas, M.; Winter, H.; Eichhorn, F.: Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: results of the NEOMUN trial. JOURNAL FOR IMMUNOTHERAPY OF CANCER 13 (8), e011874 (2025)

Rako, Z. A.; Cekay, M.; Yogeswaran, A.; Yildiz, S.; Arndt, P. F.; Kremer, N.; Schaefer, S.; Janetzko, P.; Thal, B. R.; Mummert, C. M. et al.; Franken, J. K.; Soethe, H.; Werner, H. F.; Dumitrascu, R.; Grimminger, F.; Ghofrani, H. A.; Pullamsetti, S. S.; Seeger, W.; Naeije, R.; Savai, R.; Eul, B.; Tello, K.: Echocardiographic Measure of Right Ventricular-Pulmonary Arterial Coupling Predicts Survival in Lung Cancer. ANNALS OF THE AMERICAN THORACIC SOCIETY 22 (7), pp. 1071 - 1078 (2025)

Dutzmann, J.; Daniel, J.-M.; Korte, L.; Kloss, F. J.; Knoepp, K.; Kalies, K.; Croce, K. J.; Herbst, T. J.; Huibregtse, B.; Vogt, F. J. et al.; Offermanns, S.; Bauersachs, J.; Sedding, D. G.: Adventitial Fibroblasts Release Interleukin 6 After Vascular Injury and Induce Smooth Muscle Cell Proliferation and Neointima Formation. JOURNAL OF THE AMERICAN HEART ASSOCIATION 14 (14), e040143 (2025)

Shao, J.; Kwon, J.; Wang, T.; Guenther, S.; Tombor, L. S.; Warwick, T.; Shaheryar, Z.; Brandes, R. P.; Dimmeler, S.; Wenzel, J. et al.; Offermanns, S.; Schwaninger, M.; Wettschureck, N.: Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. NATURE COMMUNICATIONS 16 (1), 6232 (2025)

Jafari, L.; Wiedenroth, C. B.; Kriechbaum, S. D.; Gruen, D.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Spaeth, A. M.; Cherian, A. V.; Troidl, C. et al.; Wilhelm, J.; Keranov, S.; Keller, T.; Kojonazarov, B.; Schermuly, R. T.; Guth, S.; Doerr, O.; Nef, H.; Boehm, M.; Spiekerkoetter, E.; Leszek, P.; Varga, Z. V.; Ferdinandy, P.; Ghofrani, H. A.; Dorfmueller, P.; Weissmann, N.; Hamm, C. W.; Mayer, E.; Seeger, W.; Liebetrau, C.; Pullamsetti, S. S.: Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery. NATURE CARDIOVASCULAR RESEARCH 4 (7) (2025)