Scientific Publications

Eichhorn, F.; Weigert, A.; Nandigama, R.; Klotz V, L.; Kriegsmann, M.; Allgaeuer, M.; Muley, T.; Christopoulos, P.; Savai, R.; Eichhorn, M. E. et al.; Winter, H.: Prognostic Impact of the Immune-Cell Infiltrate in N1-Positive Non-Small-Cell Lung Cancer. CLINICAL LUNG CANCER 24 (8) (2023)

Carletti, A.; Gavaia, P. J.; Cancela, M. L.; Laize, V.: Metabolic bone disorders and the promise of marine osteoactive compounds. CELLULAR AND MOLECULAR LIFE SCIENCES 81 (1), 11 (2023)

Martin, T. P.; MacDonald, E. A.; Bradley, A.; Watson, H.; Saxena, P.; Rog-Zielinska, E. A.; Raheem, A.; Fisher, S.; Elbassioni, A. A. M.; Almuzaini, O. et al.; Booth, C.; Campbell, M.; Riddell, A.; Herzyk, P.; Blyth, K.; Nixon, C.; Zentilin, L.; Berry, C.; Braun, T.; Giacca, M.; McBride, M. W.; Nicklin, S. A.; Cameron, E. R.; Loughrey, C. M.: Ribonucleicacid interference or small molecule inhibition of Runx1 in the border zone prevents cardiac contractile dysfunction following myocardial infarction. CARDIOVASCULAR RESEARCH 119 (16), pp. 2663 - 2671 (2023)

Marx, D.; Alnouri, M. W.; Clemens, S.; Gedschold, R.; Riedel, Y.; Al Hamwi, G.; Pillaiyar, T.; Hockemeyer, J.; Namasivayam, V.; Mueller, C. E.: Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4). JOURNAL OF MEDICINAL CHEMISTRY 66 (23), pp. 15674 - 15698 (2023)

Trif, C.; Banica, A.-M.; Manolache, A.; Anghel, S. A.; Hutanu, D.-E.; Stratulat, T.; Badea, R.; Oprita, G.; Selescu, T.; Petrescu, S. M. et al.; Sisignano, M.; Offermanns, S.; Babes, A.; Tunaru , S.: Inhibition of TRPM8 function by prostacyclin receptor agonists requires coupling to Gq/11 proteins. BRITISH JOURNAL OF PHARMACOLOGY (2023)

Jiang, C.; Liu, Y.; Zhao, W.; Yang, Y.; Ren, Z.; Wang, X.; Hao, D.; Du, H.; Yin, S.: microRNA-365 attenuated intervertebral disc degeneration through modulating nucleus pulposus cell apoptosis and extracellular matrix degradation by targeting EFNA3. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2023)

Eichstaedt, C. A.; Bikou, O.; Sommer, N.; Schermuly, R. T.; Pullamsetti, S. S.; Weissmann, N.; Harbaum, L.; Tabeling, C.; Wissmueller, M.; Foris, V. et al.; Kuebler, W. M.; Hinderhofer, K.; Olschewski, A.; Kwapiszewska, G.: Genetic diagnostics and molecular approaches in pulmonary arterial hypertension. PNEUMOLOGIE 77 (11), pp. 862 - 870 (2023)

Latimer, M. N.; Williams, L. J.; Shanmugan, G.; Carpenter, B.; Lazar, M. A.; Dierickx, P.; Young, M. E.: Cardiomyocyte-specific disruption of the circadian BMAL1-REV-ERBα/β regulatory network impacts distinct miRNA species in the murine heart. COMMUNICATIONS BIOLOGY 6 (1), 1149 (2023)

Guo, X.; Jiang, C.; Chen, Z.; Wang, X.; Hong, F.; Hao, D.: Regulation of the JAK/STAT signaling pathway in spinal cord injury: an updated review. FRONTIERS IN IMMUNOLOGY 14, 1276445 (2023)

Balla, H.; Borsodi, K.; Orsy, P.; Horvath, B.; Molnar, P. J.; Lenart, A.; Kosztelnik, M.; Ruisanchez, E.; Wess, J.; Offermanns, S. et al.; Nyirady, P.; Benyo, Z.: Intracellular signaling pathways of muscarinic acetylcholine receptor-mediated detrusor muscle contractions. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 325 (5), pp. F618 - F628 (2023)

Balla, H.; Borsodi, K.; Orsy, P.; Horvath, B.; Molnar, P. J.; Lenart, A.; Kosztelnik, M.; Ruisanchez, E.; Wess, J.; Offermanns, S. et al.; Nyirady, P.; Benyo, Z.: Intracellular signaling pathways of muscarinic acetylcholine receptor-mediated detrusor muscle contractions. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 325 (5), pp. F618 - F628 (2023)

Bonnavion, R.; Liu, S.; Kawase, H.; Roquid, K. A.; Offermanns, S.: Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5). FRONTIERS IN PHARMACOLOGY 14, 1297596 (2023)

Hu, J.; Leisegang, M. S.; Looso, M.; Drekolia, M.-K.; Wittig, J.; Mettner, J.; Karantanou, C.; Kyselova, A.; Dumbovic, G.; Li, X. et al.; Li, Y.; Guenther, S.; John, D.; Siragusa, M.; Zukunft, S.; Oo, J.; Wittig, I.; Hille, S.; Weigert, A.; Knapp, S.; Brandes, R. P.; Muller, O. J.; Papapetropoulos, A.; Sigala, F.; Dobreva, G.; Kojonazarov, B.; Fleming, I.; Bibli, S.-I.: Disrupted Binding of Cystathionine gamma-Lyase to p53 Promotes Endothelial Senescence. Circulation research (2023)

Hirani, D. V.; Thielen, F.; Mansouri, S.; Danopoulos, S.; Vohlen, C.; Haznedar-Karakaya, P.; Mohr, J.; Wilke, R.; Selle, J.; Grosch, T. et al.; Mizik, I.; Odenthal, M.; Alvira, C. M.; Kuiper-Makris, C.; Pryhuber, G. S.; Pallasch, C.; van Koningsbruggen-Rietschel, S.; Al-Alam, D.; Seeger, W.; Savai, R.; Doetsch, J.; Alcazar, M. A. A.: CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia. INFLAMMATION AND REGENERATION 43 (1), 52 (2023)

Bosnakovski, D.; Toso, E. A.; Ener, E. T.; Gearhart, M. D.; Yin, L.; Luttmann, F. F.; Magli, A.; Shi, K.; Kim, J.; Aihara, H. et al.; Kyba, M.: Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein. ISCIENCE 26 (10), 107823 (2023)

Takatsu, F.; Suzawa, K.; Tomida, S.; Thu, Y. M.; Sakaguchi, M.; Toji, T.; Ohki, M.; Tsudaka, S.; Date, K.; Matsuda, N. et al.; Iwata, K.; Zhu, Y.; Nakata, K.; Shien, K.; Yamamoto, H.; Nakayama, A.; Okazaki, M.; Sugimoto, S.; Toyooka, S.: Periostin secreted by cancer-associated fibroblasts promotes cancer progression and drug resistance in non-small cell lung cancer. JOURNAL OF MOLECULAR MEDICINE-JMM (2023)

Farin, H. F.; Mosa, M. H.; Ndreshkjana, B.; Grebbin, B. M.; Ritter, B.; Menche, C.; Kennel, K. B.; Ziegler, P. K.; Szabo, L.; Bollrath, J. et al.; Rieder, D.; Michels, B. E.; Kress, A.; Bozlar, M.; Darvishi, T.; Stier, S.; Kur, I.-M.; Bankov, K.; Kesselring, R.; Fichtner-Feigl, S.; Bruene, B.; Goetze, T. O.; Al-Batran, S.-E.; Brandts, C. H.; Bechstein, W. O.; Wild, P. J.; Weigert, A.; Mueller, S.; Knapp, S.; Trajanoski, Z.; Greten, F. R.: Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses. CANCER DISCOVERY 13 (10), pp. 2192 - 2211 (2023)

Rubio, K.; Mueller, J. M.; Mehta, A.; Watermann, I.; Olchers, T.; Koch, I.; Wessels, S.; Schneider, M. A.; Araujo-Ramos, T.; Singh, I. et al.; Kugler, C.; Stoleriu, M. G.; Kriegsmann, M.; Eichhorn, M.; Muley, T.; Merkel, O. M.; Braun, T.; Ammerpohl, O.; Reck, M.; Tresch, A.; Barreto, G.: Preliminary results from the EMoLung clinical study showing early lung cancer detection by the LC score. DISCOVER ONCOLOGY 14 (1), 181 (2023)

Agarwal, P.; Cadart, C.; Fort, L.; Gahan, J.; Greenspan, L.; Juan, T.; Kameneva, P.; Miao, Y.: Pathway to Independence: the future of developmental biology. DEVELOPMENT 150 (19), dev202360 (2023)

Alexander, S. P. H.; Christopoulos, A.; Davenport, A. P.; Kelly, E.; Mathie, A. A.; Peters, J. A.; Veale, E. L.; Armstrong, J. F.; Faccenda, E.; Harding, S. D. et al.; Davies, J. A.; Abbracchio, M. P.; Abraham, G.; Agoulnik, A.; Alexander, W.; Al-hosaini, K.; Baeck, M.; Baker, J. G.; Barnes, N. M.; Bathgate, R.; Beaulieu, J.-M.; Beck-Sickinger, A. G.; Behrens, M.; Bernstein, K. E.; Bettler, B.; Birdsall, N. J. M.; Blaho, V.; Boulay, F.; Bousquet, C.; Braeuner-Osborne, H.; Burnstock, G.; Calo, G.; Castano, J. P.; Catt, K. J.; Ceruti, S.; Chazot, P.; Chiang, N.; Chini, B.; Chun, J.; Cianciulli, A.; Civelli, O.; Clapp, L. H.; Couture, R.; Cox, H. M.; Csaba, Z.; Dahlgren, C.; Dent, G.; Douglas, S. D.; Dournaud, P.; Eguchi, S.; Escher, E.; Filardo, E. J.; Fong, T.; Fumagalli, M.; Gainetdinov, R. R.; Garelja, M. L.; de Gasparo, M.; Gerard, C.; Gershengorn, M.; Gobeil, F.; Goodfriend, T. L.; Goudet, C.; Graetz, L.; Gregory, K. J.; Gundlach, A. L.; Hamann, J.; Hanson, J.; Hauger, R. L.; Hay, D. L.; Heinemann, A.; Herr, D.; Hollenberg, M. D.; Holliday, N. D.; Horiuchi, M.; Hoyer, D.; Hunyady, L.; Husain, A.; Ijzerman, A. P.; Inagami, T.; Jacobson, K. A.; Jensen, R. T.; Jockers, R.; Jonnalagadda, D.; Karnik, S.; Kaupmann, K.; Kemp, J.; Kennedy, C.; Kihara, Y.; Kitazawa, T.; Kozielewicz, P.; Kreienkamp, H.-J.; Kukkonen, J. P.; Langenhan, T.; Larhammar, D.; Leach, K.; Lecca, D.; Lee, J. D.; Leeman, S. E.; Leprince, J.; Li, X. X.; Lolait, S. J.; Lupp, A.; Macrae, R.; Maguire, J.; Malfacini, D.; Mazella, J.; Mcardle, C. A.; Melmed, S.; Michel, M. C.; Miller, L. J.; Mitolo, V.; Mouillac, B.; Mueller, C. E.; Murphy, P. M.; Nahon, J.-L.; Ngo, T.; Norel, X.; Nyimanu, D.; O'Carroll, A.-M.; Offermanns, S.; Panaro, M. A.; Parmentier, M.; Pertwee, R. G.; Pin, J.-P.; Prossnitz, E. R.; Quinn, M.; Ramachandran, R.; Ray, M.; Reinscheid, R. K.; Rondard, P.; Rovati, G. E.; Ruzza, C.; Sanger, G. J.; Schoeneberg, T.; Schulte, G.; Schulz, S.; Segaloff, D. L.; Serhan, C. N.; Singh, K. D.; Smith, C. M.; Stoddart, L. A.; Sugimoto, Y.; Summers, R.; Tan, V. P.; Thal, D.; Thomas, W. (. W.; Timmermans, P. B. M. W. M.; Tirupula, K.; Toll, L.; Tulipano, G.; Unal, H.; Unger, T.; Valant, C.; Vanderheyden, P.; Vaudry, D.; Vaudry, H.; Vilardaga, J.-P.; Walker, C. S.; Wang, J. M.; Ward, D. T.; Wester, H.-J.; Willars, G. B.; Williams, T. L.; Woodruff, T. M.; Yao, C.; Ye, R. D.: The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors. BRITISH JOURNAL OF PHARMACOLOGY 180 (2), pp. S23 - S144 (2023)