Wissenschaftliche Publikationen

Petry, S. F.; Kandula, N. D.; Guenther, S.; Helker, C.; Schagdarsurengin, U.; Linn, T.: Valproic Acid Initiates Transdifferentiation of the Human Ductal Adenocarcinoma Cell-line Panc-1 Into alpha-Like Cells. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES (2022)

Chu, Z.; Gu, L.; Hu, Y.; Zhang, X.; Li, M.; Chen, J.; Teng, D.; Huang, M.; Shen, C.-H.; Cai, L. et al.; Yoshida, T.; Qi, Y.; Niu, Z.; Feng, A.; Geng, S.; Frederick, D. T.; Specht, E.; Piris, A.; Sullivan, R. J.; Flaherty, K. T.; Boland, G. M.; Georgopoulos, K.; Liu, D.; Shi, Y.; Zheng, B.: STAG2 regulates interferon signaling in melanoma via enhancer loop reprogramming. NATURE COMMUNICATIONS 13 (1), 1859 (2022)

El-Sammak, H.; Yang, B.; Guenther, S.; Chen, W.; Marin-Juez, R.; Stainier, D. Y. R.: A Vegfc-Emilin2a-Cxcl8a Signaling Axis Required for Zebrafish Cardiac Regeneration. CIRCULATION RESEARCH 130 (7), S. 1014 - 1029 (2022)

Elwakeel, E.; Brueggemann, M.; Wagih, J.; Lityagina, O.; Elewa, M. A. F.; Han, Y.; Froemel, T.; Popp, R.; Nicolas, A. M.; Schreiber, Y. et al.; Gradhand, E.; Thomas, D.; Nuesing, R.; Steinmetz-Spaeh, J.; Savai, R.; Fokas, E.; Fleming, I.; Greten, F. R.; Zarnack, K.; Bruene, B.; Weigert, A.: Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis. CANCER RESEARCH 82 (7), S. 1380 - 1395 (2022)

Olmedo-Suarez, M. A.; Ramirez-Diaz, I.; Perez-Gonzalez, A.; Molina-Herrera, A.; Coral-Garcia, M. A.; Lobato, S.; Sarvari, P.; Barreto, G.; Rubio, K.: Epigenetic Regulation in Exposome-Induced Tumorigenesis: Emerging Roles of ncRNAs. BIOMOLECULES 12 (4), 513 (2022)

Coxam, B.; Collins, R. T.; Hussmann, M.; Huisman, Y.; Meier, K.; Jung, S.; Bartels-Klein, E.; Szymborska, A.; Finotto, L.; Helker, C. S. M. et al.; Stainier, D. Y. R.; Schulte-Merker, S.; Gerhardt, H.: Svep1 stabilises developmental vascular anastomosis in reduced flow conditions. DEVELOPMENT 149 (6), dev199858 (2022)

Engelhardt, S.; Dimmeler, S.; Heim, C.; Baer, C.; Boettger, T.; Boon, R.; Brandes, R. P.; Braun, T.; Dueck, A.; Gagneur, J. et al.; Grote, P.; Holdt, L. M.; Jae, N.; Krishnan, J.; Kupatt, C.; Laugwitz, K. -.; Leisegang, M. S.; Maegdefessel, L.; Meitinger, T.; Moretti, A.; Mueller-McNicoll, M.; Sattler, M.; Schnieke, A.; Schulz, M.; Schunkert, H.; Schwalbe, H.; Teupser, D.; Thum, T.; Weber, C.; Wittig, I.; Zarnack, K.: Noncoding RNA in the cardiovascular system Collaborative research centre/transregio (SFB-TRR 267). KARDIOLOGE 16 (2), S. 100 - 108 (2022)

Hansen, L.; Lohfink, N.; Vutukuri, R.; Kestner, R.-I.; Trautmann, S.; Hecht, M.; Wagner, P. V.; Spitzer, D.; Khel, M. I.; Macas, J. et al.; Ferreiros, N.; Gurke, R.; Guenther, S.; Pfeilschifter, W.; Devraj, K.: Endothelial Sphingosine-1-Phosphate Receptor 4 Regulates Blood-Brain Barrier Permeability and Promotes a Homeostatic Endothelial Phenotype. JOURNAL OF NEUROSCIENCE 42 (10), S. 1908 - 1929 (2022)

Seredinski, S.; Boos, F.; Guenther, S.; Oo, J. A.; Warwick, T.; Ponce, J. I.; Lillich, F. F.; Proschak, E.; Knapp, S.; Gilsbach, R. et al.; Pflueger-Mueller, B.; Brandes, R. P.; Leisegang, M. S.: DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. MOLECULAR THERAPY-NUCLEIC ACIDS 27, S. 1023 - 1035 (2022)

Keshavarz, M.; Tabrizi, S. F.; Ruppert, A.-L.; Pfeil, U.; Schreiber, Y.; Klein, J.; Brandenburger, I.; Lochnit, G.; Bhushan, S.; Perniss, A. et al.; Deckmann, K.; Hartmann, P.; Meiners, M.; Mermer, P.; Rafiq, A.; Winterberg, S.; Papadakis, T.; Thomas, D.; Angioni, C.; Oberwinkler, J.; Chubanov, V.; Gudermann, T.; Gaertner, U.; Offermanns, S.; Schuetz, B.; Kummer, W.: Cysteinyl leukotrienes and acetylcholine are biliary tuft cell cotransmitters. SCIENCE IMMUNOLOGY 7 (69), eabf6734 (2022)

Kudryashova V, T.; Dabral, S.; Nayakanti, S.; Ray, A.; Goncharov, D. A.; Avolio, T.; Shen, Y.; Rode, A.; Pena, A.; Jiang, L. et al.; Lin, D.; Baust, J.; Bachman, T. N.; Graumann, J.; Ruppert, C.; Guenther, A.; Schmoranzer, M.; Grobs, Y.; Lemay, S. E.; Tremblay, E.; Breuils-Bonnet, S.; Boucherat, O.; Mora, A. L.; DeLisser, H.; Zhao, J.; Zhao, Y.; Bonnet, S.; Seeger, W.; Pullamsetti, S. S.; Goncharova, E. A.: Noncanonical HIPPO/MST Signaling via BUB3 and FOXO Drives Pulmonary Vascular Cell Growth and Survival. CIRCULATION RESEARCH 130 (5), S. 760 - 778 (2022)

Wang, X.; Jiang, C.; Zhang, Y.; Chen, Z.; Fan, H.; Zhang, Y.; Wang, Z.; Tian, F.; Li, J.; Yang, H. et al.; Hao, D.: The promoting effects of activated olfactory ensheathing cells on angiogenesis after spinal cord injury through the PI3K/Akt pathway. CELL AND BIOSCIENCE 12 (1), 23 (2022)

Briquet, M.; Rocher, A.-B.; Alessandri, M.; Rosenberg, N.; Abrantes, H. d. C.; Wellbourne-Wood, J.; Schmuziger, C.; Ginet, V.; Puyal, J.; Pralong, E. et al.; Daniel, R. T.; Offermanns, S.; Chatton, J.-Y.: Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 0271678X221080324 (2022)

Schebb, N. H.; Kuehn, H.; Kahnt, A. S.; Rund, K. M.; O'Donnell, V. B.; Flamand, N.; Peters-Golden, M.; Jakobsson, P.-J.; Weylandt, K. H.; Rohwer, N. et al.; Murphy, R. C.; Geisslinger, G.; FitzGerald, G. A.; Hanson, J.; Dahlgren, C.; Alnouri, M. W.; Offermanns, S.; Steinhilber, D.: Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators-What is the Evidence so far? FRONTIERS IN PHARMACOLOGY 13, 838782 (2022)

Chen, Y.-C.; He, X.-L.; Qi, L.; Shi, W.; Yuan, L.-W.; Huang, M.-Y.; Xu, Y.-L.; Chen, X.; Gu, L.; Zhang, L.-L. et al.; Lu, J.-J.: Myricetin inhibits interferon-gamma-induced PD-L1 and IDO1 expression in lung cancer cells. BIOCHEMICAL PHARMACOLOGY 197, 114940 (2022)

Li, Z.; Peng, M.; Chen, P.; Liu, C.; Hu, A.; Zhang, Y.; Peng, J.; Liu, J.; Li, Y.; Li, W. et al.; Zhu, W.; Guan, D.; Zhang, Y.; Chen, H.; Li, J.; Fan, D.; Huang, K.; Lin, F.; Zhang, Z.; Guo, Z.; Luo, H.; He, X.; Zhu, Y.; Li, L.; Huang, B.; Cai, W.; Gu, L.; Lu, Y.; Deng, K.; Yan, L.; Chen, S.: Imatinib and methazolamide ameliorate COVID-19-induced metabolic complications via elevating ACE2 enzymatic activity and inhibiting viral entry. CELL METABOLISM 34 (3), S. 424 - 440 (2022)

Uenaka, M.; Yamashita, E.; Kikuta, J.; Morimoto, A.; Ao, T.; Mizuno, H.; Furuya, M.; Hasegawa, T.; Tsukazaki, H.; Sudo, T. et al.; Nishikawa, K.; Okuzaki, D.; Motooka, D.; Kosaka, N.; Sugihara, F.; Boettger, T.; Braun, T.; Ochiya, T.; Ishii, M.: Osteoblast-derived vesicles induce a switch from bone-formation to bone-resorption in vivo. NATURE COMMUNICATIONS 13 (1), 1066 (2022)

Muller, N.; Warwick, T.; Noack, K.; Malacarne, P. F.; Cooper, A. J. L.; Weissmann, N.; Schroder, K.; Brandes, R. P.; Rezende, F.: Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Antioxidants (Basel, Switzerland) 11 (2), S. 434 (2022)

Yin, W.; Liontos, A.; Koepke, J.; Ghoul, M.; Mazzocchi, L.; Liu, X.; Lu, C.; Wu, H.; Fysikopoulos, A.; Sountoulidis, A. et al.; Seeger, W.; Ruppert, C.; Gunther, A.; Stainier, D. Y. R.; Samakovlis, C.: An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea. DEVELOPMENT 149 (3), dev199804 (2022)

Kubin, T.; Gajawada, P.; Bramlage, P.; Hein, S.; Berge, B.; Cetinkaya, A.; Burger, H.; Schoenburg, M.; Schaper, W.; Choi, Y.-H. et al.; Richter, M.: The Role of Oncostatin M and Its Receptor Complexes in Cardiomyocyte Protection, Regeneration, and Failure. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (3), 1811 (2022)