Wissenschaftliche Publikationen

Gogiraju, R.; Gachkar, S.; Velmeden, D.; Bochenek, M. L.; Zifkos, K.; Hubert, A.; Muenzel, T.; Offermanns, S.; Schaefer, K.: Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury. THROMBOSIS AND HAEMOSTASIS 122 (10), S. 1814 - 1826 (2022)

Garcia-Gonzalez, C.; Dieterich, C.; Maroli, G.; Wiesnet, M.; Wietelmann, A.; Li, X.; Yuan, X.; Graumann, J.; Stellos, K.; Kubin, T. et al.; Schneider, A.; Braun, T.: ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. CIRCULATION RESEARCH 131 (7), S. 580 - 597 (2022)

Solerno, L. M.; Sobol, N. T.; Gottardo, M. F.; Capobianco, C. S.; Ferrero, M. R.; Vasquez, L.; Alonso, D. F.; Garona, J.: Propranolol blocks osteosarcoma cell cycle progression, inhibits angiogenesis and slows xenograft growth in combination with cisplatin-based chemotherapy. SCIENTIFIC REPORTS 12 (1), 15058 (2022)

Baig, M. S.; Rajpoot, S.; Ohishi, T.; Savai, R.; Seidel, S.; Kamennaya, N. A.; Bezsonov, E. E.; Orekhov, A. N.; Mahajan, P.; Solanki, K. et al.; Saqib, U.: Anti-lung cancer properties of cyanobacterial bioactive compounds. ARCHIVES OF MICROBIOLOGY 204 (10), 603 (2022)

Ellis, J. L.; Evason, K. J.; Zhang, C.; Fourman, M. N.; Liu, J.; Ninov, N.; Delous, M.; Vanhollebeke, B.; Fiddes, I.; Otis, J. P. et al.; Houvras, Y.; Farber, S. A.; Xu, X.; Lin, X.; Stainier, D. Y. R.; Yin, C.: A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish. HEPATOLOGY COMMUNICATIONS (2022)

Medrano-Garcia, S.; Morales-Cano, D.; Barreira, B.; Vera-Zambrano, A.; Kumar, R.; Kosanovic, D.; Schermuly, R. T.; Graham, B. B.; Perez-Vizcaino, F.; Mathie, A. et al.; Savai, R.; Pullamseti, S.; Butrous, G.; Fernandez-Malave, E.; Cogolludo, A.: HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape. CELLS 11 (15), 2414 (2022)

Woods, M. L.; Weiss, A.; Sokol, A. M.; Graumann, J.; Boettger, T.; Richter, A. M.; Schermuly, R. T.; Dammann, R. H.: Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. CANCER GENE THERAPY (2022)

Selle, J.; Dinger, K.; Jentgen, V.; Zanetti, D.; Will, J.; Georgomanolis, T.; Vohlen, C.; Wilke, R.; Kojonazarov, B.; Klymenko, O. et al.; Mohr, J.; Koningsbruggen-Rietschel, S. v.; Rhodes, C. J.; Ulrich, A.; Hirani, D.; Nestler, T.; Odenthal, M.; Mahabir, E.; Nayakanti, S.; Dabral, S.; Wunderlich, T.; Priest, J.; Seeger, W.; Doetsch, J.; Pullamsetti, S. S.; Alcazar, M. A. A.: Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life. NATURE COMMUNICATIONS 13 (1), 4352 (2022)

Hu, B.; Lelek, S.; Spanjaard, B.; El-Sammak, H.; Simoes, M. G.; Mintcheva, J.; Aliee, H.; Schaefer, R.; Meyer, A. M.; Theis, F. et al.; Stainier, D. Y. R.; Panakova, D.; Junker, J. P.: Origin and function of activated fibroblast states during zebrafish heart regeneration. NATURE GENETICS (2022)

Georgieva, A. M.; Guo, X.; Bartkuhn, M.; Guenther, S.; Kuenne, C.; Smolka, C.; Atzberger, A.; Gaertner, U.; Mamchaoui, K.; Bober, E. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression. NATURE COMMUNICATIONS 13 (1), 4184 (2022)

Xu, R.; Hoess, C.; Swiercz, J. M.; Brandt, D. T.; Lutz, V.; Petersen, N.; Li, R.; Zhao, D.; Oleksy, A.; Creigh-Pulatmen, T. et al.; Trokter, M.; Fedorova, M.; Atzberger, A.; Strandby, R. B.; Olsen, A. A.; Achiam, M. P.; Matthews, D.; Huber, M.; Groene, H.-J.; Offermanns, S.; Worzfeld, T.: A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers. SCIENCE TRANSLATIONAL MEDICINE 14 (654), eabf1922 (2022)

Sommer, N.; Theine, F. F.; Pak, O.; Tello, K.; Richter, M.; Gall, H.; Wilhelm, J.; Savai, R.; Weissmann, N.; Seeger, W. et al.; Ghofrani, H. A.; Hecker, M.: Mitochondrial Respiration in Peripheral Blood Mononuclear Cells Negatively Correlates with Disease Severity in Pulmonary Arterial Hypertension. JOURNAL OF CLINICAL MEDICINE 11 (14), 4132 (2022)

Shahzad, T.; Chao, C.-M.; Hadzic, S.; Behnke, J.; Biebach, L.; Boettcher-Friebertshaeuser, E.; Wilhelm, J.; Hilgendorff, A.; Zimmer, K.-P.; Morty, R. E. et al.; Bellusci, S.; Ehrhardt, H.: TRAIL protects the immature lung from hyperoxic injury. CELL DEATH & DISEASE 13 (7), 614 (2022)

Ferrante, F.; Giaimo, B. D.; Friedrich, T.; Sugino, T.; Mertens, D.; Kugler, S.; Gahr, B. M.; Just, S.; Pan, L.; Bartkuhn, M. et al.; Potente, M.; Oswald, F.; Borggrefe, T.: Hydroxylation of the NOTCH1 intracellular domain regulates Notch signaling dynamics. CELL DEATH & DISEASE 13 (7), 600 (2022)

Vieujean, S.; Caron, B.; Haghnejad, V.; Jouzeau, J.-Y.; Netter, P.; Heba, A.-C.; Ndiaye, N. C.; Moulin, D.; Barreto, G.; Danese, S. et al.; Peyrin-Biroulet, L.: Impact of the Exposome on the Epigenome in Inflammatory Bowel Disease Patients and Animal Models. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (14), 7611 (2022)

Kuhnert, S.; Mansouri, S.; Rieger, M. A.; Savai, R.; Avci, E.; Diaz-Pina, G.; Padmasekar, M.; Looso, M.; Hadzic, S.; Acker, T. et al.; Klatt, S.; Wilhelm, J.; Fleming, I.; Sommer, N.; Weissmann, N.; Vogelmeier, C.; Bals, R.; Zeiher, A.; Dimmeler, S.; Seeger, W.; Pullamsetti, S. S.: Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD. CELLS 11 (13), 2121 (2022)

Gupta, R.; Wang, M.; Ma, Y.; Offermanns, S.; Whim, M. D.: The beta-Hydroxybutyrate-GPR109A Receptor Regulates Fasting-induced Plasticity in the Mouse Adrenal Medulla. ENDOCRINOLOGY 163 (7), bqac077 (2022)

Kirchhof, L.; Fouani, Y.; Knau, A.; Aslan, G. S.; Heumueller, A. W.; Wittig, I.; Mueller-McNicoll, M.; Dimmeler, S.; Jae, N.: The G3BP1-UPF1-Associated Long Non-Coding RNA CALA Regulates RNA Turnover in the Cytoplasm. NON-CODING RNA 8 (4), 49 (2022)

Kimoloi, S.; Sen, A.; Guenther, S.; Braun, T.; Brugmann, T.; Sasse, P.; Wiesner, R. J.; Pla-Martin, D.; Baris, O. R.: Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2022)

Labode, J.; Dullin, C.; Wagner, W. L.; Myti, D.; Morty, R. E.; Muehlfeld, C.: Evaluation of classifications of the monopodial bronchopulmonary vasculature using clustering methods. HISTOCHEMISTRY AND CELL BIOLOGY (2022)