Wissenschaftliche Publikationen

Nakayama, A.; Roquid, K. A.; Iring, A.; Strilic, B.; Guenther, S.; Chen, M.; Weinstein, L. S.; Offermanns, S.: Suppression of CCL2 angiocrine function by adrenomedullin promotes tumor growth. JOURNAL OF EXPERIMENTAL MEDICINE 220 (1), e20211628 (2023)

Uszczynska-Ratajczak, B.; Sugunan, S.; Kwiatkowska, M.; Migdal, M.; Carbonell-Sala, S.; Sokol, A.; Winata, C. L.; Chacinska, A.: Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish. LIFE SCIENCE ALLIANCE 6 (1), e202201514 (2023)

Oo, J. A.; Palfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomaskovic, I.; Boos, F.; Izquierdo Ponce, J.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Pham, M. D.; Krishnan, J.; Baker, A. H.; Gunther, S.; Ulrich, H. D.; Dikic, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell reports 41 (7) (2022)

Zhao, H.; Teng, D.; Yang, L.; Xu, X.; Chen, J.; Jiang, T.; Feng, A. Y.; Zhang, Y.; Frederick, D. T.; Gu, L. et al.; Cai, L.; Asara, J. M.; di Magliano, M. P.; Boland, G. M.; Flaherty, K. T.; Swanson, K. D.; Liu, D.; Rabinowitz, J. D.; Zheng, B.: Myeloid-derived itaconate suppresses cytotoxic CD8(+) T cells and promotes tumour growth. NATURE METABOLISM (2022)

Chu, X.; Lingampally, A.; Moiseenko, A.; Kheirollahi, V.; Vazquez-Armendariz, A. I.; Koepke, J.; Khadim, A.; Kiliaris, G.; Felordi, M. S.; Zabihi, M. et al.; Shalashova, I.; Alexopoulos, I.; Guenther, S.; Lebrigand, K.; Truchi, M.; Guenther, A.; Braun, T.; Mari, B.; Samakovlis, C.; Li, X.; Seeger, W.; Herold, S.; Zhang, J.-S.; Bellusci, S.; El Agha, E.: GLI1+cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration. CELLULAR AND MOLECULAR LIFE SCIENCES 79 (11), 581 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Gunther, S.; Senturk Cetin, N.; Warwick, T.; Cao, C. et al.; Boos, F.; Izquierdo Ponce, J.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pfluger-Muller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nature communications 13 (1), 6563 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Drekolia, M.-K.; Talyan, S.; Emidio, R. C.; Boon, R. A.; Guenther, S.; Looso, M.; Dumbovic, G.; Bibli, S.-I.: Unravelling the impact of aging on the human endothelial lncRNA transcriptome. FRONTIERS IN GENETICS 13, 1035380 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Merle, N.; Elmshaeuser, S.; Strassheimer, F.; Wanzel, M.; Koenig, A. M.; Funk, J.; Neumann, M.; Kochhan, K.; Helmprobst, F.; Pagenstecher, A. et al.; Nist, A.; Mernberger, M.; Schneider, A.; Braun, T.; Borggrefe, T.; Savai, R.; Timofeev, O.; Stiewe, T.: Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase. MOLECULAR CANCER 21 (1), 191 (2022)

Gogiraju, R.; Gachkar, S.; Velmeden, D.; Bochenek, M. L.; Zifkos, K.; Hubert, A.; Muenzel, T.; Offermanns, S.; Schaefer, K.: Protein Tyrosine Phosphatase 1B Deficiency in Vascular Smooth Muscle Cells Promotes Perivascular Fibrosis following Arterial Injury. THROMBOSIS AND HAEMOSTASIS 122 (10), S. 1814 - 1826 (2022)

Magadum, A.; Renikunta, H. V.; Singh, N.; Estaras, C.; Kishore, R.; Engel, F. B.: Live cell screening identifies glycosides as enhancers of cardiomyocyte cell cycle activity. FRONTIERS IN CARDIOVASCULAR MEDICINE 9, 901396 (2022)

Kimmig, L. M.; Rako, Z. A.; Ziegler, S.; Richter, M. J.; Tolou, A. G. S.; Roller, F.; Grimminger, F.; Vadasz, I.; Seeger, W.; Herold, S. et al.; Tello, K.; Matt, U.: Long-term comprehensive cardiopulmonary phenotyping of COVID-19. RESPIRATORY RESEARCH 23 (1), 263 (2022)

Garcia-Gonzalez, C.; Dieterich, C.; Maroli, G.; Wiesnet, M.; Wietelmann, A.; Li, X.; Yuan, X.; Graumann, J.; Stellos, K.; Kubin, T. et al.; Schneider, A.; Braun, T.: ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. CIRCULATION RESEARCH 131 (7), S. 580 - 597 (2022)

Solerno, L. M.; Sobol, N. T.; Gottardo, M. F.; Capobianco, C. S.; Ferrero, M. R.; Vasquez, L.; Alonso, D. F.; Garona, J.: Propranolol blocks osteosarcoma cell cycle progression, inhibits angiogenesis and slows xenograft growth in combination with cisplatin-based chemotherapy. SCIENTIFIC REPORTS 12 (1), 15058 (2022)

Baig, M. S.; Rajpoot, S.; Ohishi, T.; Savai, R.; Seidel, S.; Kamennaya, N. A.; Bezsonov, E. E.; Orekhov, A. N.; Mahajan, P.; Solanki, K. et al.; Saqib, U.: Anti-lung cancer properties of cyanobacterial bioactive compounds. ARCHIVES OF MICROBIOLOGY 204 (10), 603 (2022)

Diniz, F.; Azevedo, M.; Sousa, F.; Osorio, H.; Campos, D.; Sampaio, P.; Gomes, J.; Sarmento, B.; Reis, C. A.: Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions. MATERIALS TODAY BIO 16, 100417 (2022)

Mattonet, K.; Riemslagh, F. W.; Guenther, S.; Prummel, K. D.; Kesavan, G.; Hans, S.; Ebersberger, I.; Brand, M.; Burger, A.; Reischauer, S. et al.; Mosimann, C.; Stainier, D. Y. R.: Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. SCIENCE ADVANCES 8 (35), eabn2082 (2022)

Ellis, J. L.; Evason, K. J.; Zhang, C.; Fourman, M. N.; Liu, J.; Ninov, N.; Delous, M.; Vanhollebeke, B.; Fiddes, I.; Otis, J. P. et al.; Houvras, Y.; Farber, S. A.; Xu, X.; Lin, X.; Stainier, D. Y. R.; Yin, C.: A missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish. HEPATOLOGY COMMUNICATIONS (2022)

Rai, N.; Sydykov, A.; Kojonazarov, B.; Wilhelm, J.; Manaud, G.; Veeroju, S.; Ruppert, C.; Perros, F.; Ghofrani, H. A.; Weissmann, N. et al.; Seeger, W.; Schermuly, R. T.; Novoyatleva, T.: Targeting peptidyl-prolyl isomerase 1 in experimental pulmonary arterial hypertension. EUROPEAN RESPIRATORY JOURNAL 60 (2), 2101698 (2022)