Zeitschriftenartikel (1240)

2025
Zeitschriftenartikel
Eibach, Y.; Kreher, S.; Poetsch, M. S.; Kho, A. L.; Gaertner, U.; Clemen, C. S.; Schroeder, R.; Guo, K.; Milting, H.; Meder, B. et al.; Potente, M.; Richter, M.; Schneider, A.; Meiners, S.; Gaute, M.; Braun, T.: The deubiquitinase USP5 prevents accumulation of protein aggregates in cardiomyocytes. SCIENCE ADVANCES 11 (4), eado3852 (2025)
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Hernandez-Olmos, V.; Heering, J.; Ildefeld, N.; Ehrler, J. H. M.; Kaps, A.; Rajkumar, R.; Marinescu, B.; Kaiser, A.; Macinkovic, I.; Elewa, M. A. F. et al.; Alnouri, M. W.; Elson, L.; Schubert-Zsilavecz, M.; Kallenborn-Gerhardt, W.; Schmidtko, A.; Mueller, S.; Offermanns, S.; Steinhilber, D.; Weigert, A.; Proschak, E.: Identification of a Chemical Probe for BLT2 Activation by Scaffold Hopping. JOURNAL OF MEDICINAL CHEMISTRY 68 (2), S. 1195 - 1221 (2025)
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Juvik, B.; Falcucci, L.; Lundegaard, P. R.; Stainier, D. Y. R.: A new hypothesis to explain disease dominance. TRENDS IN GENETICS 41 (3), S. 187 - 193 (2025)
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Funk, J. S.; Klimovich, M.; Drangenstein, D.; Pielhoop, O.; Hunold, P.; Borowek, A.; Noeparast, M.; Pavlakis, E.; Neumann, M.; Balourdas, D.-I. et al.; Kochhan, K.; Merle, N.; Bullwinkel, I.; Wanzel, M.; Elmshaeuser, S.; Teply-Szymanski, J.; Nist, A.; Procida, T.; Bartkuhn, M.; Humpert, K.; Mernberger, M.; Savai, R.; Soussi, T.; Joerger, A. C.; Stiewe, T.: Deep CRISPR mutagenesis characterizes the functional diversity of TP53 mutations. NATURE GENETICS 57 (1) (2025)
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Xie, L.; Jakutis, G.; Dooley, C. M.; Guenther, S.; Kontarakis, Z.; Howard, S.; Juan, T.; Stainier, D. Y. R.: Induction of a transcriptional adaptation response by RNA destabilization events. EMBO REPORTS (2025)
2024
Zeitschriftenartikel
Cordero, J.; Swaminathan, G.; Rogel-Ayala, D. G.; Rubio, K.; Elsherbiny, A.; Mahmood, S.; Szymanski, W.; Graumann, J.; Braun, T.; Guenther, S. et al.; Dobreva, G.; Barreto, G.: Nuclear microRNA 9 mediates G-quadruplex formation and 3D genome organization during TGF-β-induced transcription. NATURE COMMUNICATIONS 15 (1), 10711 (2024)
Zeitschriftenartikel
Kothalawala, S. D.; Guenther, S.; Schuppe, H.-C.; Pilatz, A.; Wagenlehner, F.; Kliesch, S.; O'Donnell, L.; Fietz, D.: Identification of differentially expressed genes in human testis biopsies with defective spermatogenesis. REPRODUCTIVE MEDICINE AND BIOLOGY 23 (1), e12616 (2024)
Zeitschriftenartikel
Liu, X.; Gu, L.; Hao, C.; Xu, W.; Leng, F.; Zhang, P.; Li, W.: Systematic assessment of structural variant annotation tools for genomic interpretation. LIFE SCIENCE ALLIANCE 8 (3), e202402949 (2024)
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Xu, Y.; Gehlot, R.; Capon, S. J.; Albu, P. M.; Gretz, J.; Bloomekatz, J.; Mattonet, K.; Vucicevic, D.; Talyan, S.; Kikhi, K. et al.; Guenther, S.; Looso, M.; Firulli, B. A.; Sanda, M.; Firulli, A. B.; Lacadie, S. A.; Yelon, D.; Stainier, D. Y. R.: PDGFRA is a conserved HAND2 effector during early cardiac development. NATURE CARDIOVASCULAR RESEARCH 3 (12) (2024)
Zeitschriftenartikel
Xu, Y.; Gehlot, R.; Capon, S. J.; Albu, M.; Gretz, J.; Bloomekatz, J.; Mattonet, K.; Vucicevic, D.; Talyan, S.; Kikhi, K. et al.; Guenther, S.; Looso, M.; Firulli, B. A.; Sanda, M.; Firulli, A. B.; Lacadie, S. A.; Yelon, D.; Stainier, D. Y. R.: PDGFRA is a conserved HAND2 effector during early cardiac development. NATURE CARDIOVASCULAR RESEARCH 3 (12) (2024)
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Wang, Z.-Y.; Mehra, A.; Wang, Q.-C.; Gupta, S.; da Silva, A. R.; Juan, T.; Guenther, S.; Looso, M.; Detleffsen, J.; Stainier, D. Y. R. et al.; Marin-Juez, R.: flt1 inactivation promotes zebrafish cardiac regeneration by enhancing endothelial activity and limiting the fibrotic response. DEVELOPMENT 151 (23), dev203028 (2024)
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Baxan, N.; Zhao, L.; Ashek, A.; Niglas, M.; Wang, D.; Khassafi, F.; Sabrin, F.; Dubois, O.; Chen, C.-N.; Pullamsetti, S. S. et al.; Wilkins, M.; Zhao, L.: Deep phenotyping the right ventricle to establish translational MRI biomarkers for characterization of adaptive and maladaptive states in pulmonary hypertension. SCIENTIFIC REPORTS 14 (1), 29774 (2024)
Zeitschriftenartikel
Baxan, N.; Zhao, L.; Ashek, A.; Niglas, M.; Wang, D.; Khassafi, F.; Sabrin, F.; Dubois, O.; Chen, C.-N.; Pullamsetti, S. S. et al.; Wilkins, M.; Zhao, L.: Deep phenotyping the right ventricle to establish translational MRI biomarkers for characterization of adaptive and maladaptive states in pulmonary hypertension. SCIENTIFIC REPORTS 14 (1), 29774 (2024)
Zeitschriftenartikel
Seidel, L.-M.; Thudium, J.; Smith, C.; Sapehia, V.; Sommer, N.; Wujak, M.; Weissmann, N.; Seeger, W.; Schermuly, R. T.; Novoyatleva, T.: Death-associated protein kinase 1 prevents hypoxia-induced metabolic shift and pulmonary arterial smooth muscle cell proliferation in PAH. CELLULAR SIGNALLING 127, 111527 (2024)
Zeitschriftenartikel
Seidel, L.-M.; Thudium, J.; Smith, C.; Sapehia, V.; Sommer, N.; Wujak, M.; Weissmann, N.; Seeger, W.; Schermuly, R. T.; Novoyatleva, T.: Death-associated protein kinase 1 prevents hypoxia-induced metabolic shift and pulmonary arterial smooth muscle cell proliferation in PAH. CELLULAR SIGNALLING 127, 111527 (2024)
Zeitschriftenartikel
Yoshida, T.; Yoshida, S.; Inukai, K.; Kato, K.; Yura, Y.; Hattori, T.; Taki, K.; Enomoto, A.; Ohashi, K.; Okumura, T. et al.; Ouchi, N.; Kawase, H.; Wettschureck, N.; Offermanns, S.; Murohara, T.; Takefuji, M.: ALPK2 prevents cardiac diastolic dysfunction in heart failure with preserved ejection fraction. FASEB JOURNAL 38 (22), e70192 (2024)
Zeitschriftenartikel
Zierden, M.; Berghausen, E. M.; Gnatzy-Feik, L.; Millarg, C.; Picard, F. S. R.; Kiljan, M.; Geissen, S.; Polykratis, A.; Zimmermann, L.; Nies, R. J. et al.; Pasparakis, M.; Baldus, S.; Valasarajan, C.; Pullamsetti, S. S.; Winkels, H.; Vantler, M.; Rosenkranz, S.: Hematopoietic PI3KS deficiency aggravates murine atherosclerosis through impairment of Tregs. JCI INSIGHT 9 (22), e155626 (2024)
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Teichmann, T.; Pflueger-Mueller, B.; Gimenez, V. M. M.; Sailer, F.; Dirks, H.; Zehr, S.; Warwick, T.; Brettner, F.; Munoz-Tello, P.; Zimmer, A. et al.; Tegeder, I.; Thomas, D.; Gurke, R.; Guenther, S.; Heering, J.; Proschak, E.; Geisslinger, G.; Bibli, I.-S.; zu Heringdorf, D. M.; Manucha, W.; Windbergs, M.; Knapp, S.; Weigert, A.; Leisegang, M. S.; Kojetin, D.; Brandes, R. P.: The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors. BRITISH JOURNAL OF PHARMACOLOGY (2024)
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Prieto-Garcia, C.; Matkovic, V.; Mosler, T.; Li, C.; Liang, J.; Oo, J. A.; Haidle, F.; Macinkovic, I.; Cabrera-Orefice, A.; Berkane, R. et al.; Giuliani, G.; Xu, F.; Jacomin, A.-C.; Tomaskovic, I.; Basoglu, M.; Hoffmann, M. E.; Rathore, R.; Cetin, R.; Boutguetait, D.; Bozkurt, S.; Canas, M. C. H.; Keller, M.; Busam, J.; Shah, V. J.; Wittig, I.; Kaulich, M.; Beli, P.; Galej, W. P.; Ebersberger, I.; Wang, L.; Muench, C.; Stolz, A.; Brandes, R. P.; Tse, W. K. F.; Eimer, S.; Stainier, D. Y. R.; Legewie, S.; Zarnack, K.; Mueller-McNicoll, M.; Dikic, I.: Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy. SCIENCE 386 (6723), S. 768 - 776 (2024)
Zeitschriftenartikel
Hebchen, D. M.; Schader, T.; Spaeth, M.; Mueller, N.; Graumann, J.; Schroeder, K.: NoxO1 regulates EGFR signaling by its interaction with Erbin. REDOX BIOLOGY 77, 103396 (2024)
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