Publications

Cartura, M.; Aliraj, B.; Szymanski, W.; Park, C.; Ferrario, G.; Rezende, F.; Guven, B.; Bleckwehl, T.; Sachs, N.; Magdefessel, L. et al.; Dimmeler, S.; Muller, O. J.; Jo, H.; Offermanns, S.; Hayat, S.; Brandes, R. P.; Munch, C.; Graumann, J.; Weigert, A.; Fleming, I.; Siragusa, M.: Immunomodulatory endothelial cells contribute to T-cell recruitment and activation via antigen presentation on MHC II. CARDIOVASCULAR RESEARCH 122 (12), pp. 1672 - 1687 (2026)

Kwon, J.; Persechino, M.; Shao, J.; Shamsara, J.; Spitznagel, B.; Salwig, I.; Sanda, M.; Offermanns, S.; Kolb, P.; Wettschureck, N.: Small molecule inhibitor of orphan GPCR dimerization improves host defense and blood pressure control in mice. JOURNAL OF CLINICAL INVESTIGATION 136 (15), e203162 (2026)

Mansouri, S.; Hesami, G.; Ambikan, A.; Karger, A.; Klatt, S.; Neogi, U.; Kurakula, K. B.; Aliraj, B.; Miller, A.; Petrova, B. et al.; Sanda, M.; Sirait-Fischer, E.; Guenther, S.; Kuenne, C.; Ruppert, C.; Alkoudmani, I.; Gattenlohner, S.; Zukunft, S.; Fleming, I.; Haschemi, A.; Stiewe, T.; Grimminger, F.; Reck, M.; Weigert, A.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: IRG1/itaconate rewires macrophage and lung tumor metabolism through G6PD inhibition. CELL METABOLISM 38 (7), pp. 1460 - 1477 (2026)

Raheja, M.; Guven, B.; Szymanski, W.; Gunther, S.; Kuenne, C.; Rakultsev, V.; Segarra, M.; Bozkurt, S.; Munch, C.; Kaulich, M. et al.; Graumann, J.; Fleming, I.; Siragusa, M.: A microprotein encoded by FERMT3 modulates endothelial cell protein catabolism and induces cell cycle arrest and senescence. CELL COMMUNICATION AND SIGNALING 24 (1), 372 (2026)

Siragusa, M.; Graumann, J.; Kuenne, C.; Gunther, S.; Jeratsch, S.; Guven, B.; Susser, S.; Talyan, S.; Bezuneh, B.; Matthess, Y. et al.; Cartura, M.; Zhou, X.; Cho, H.; Sachs, N.; Maegdefessel, L.; Muller, O. J.; Troidl, C.; Nef, H. M.; Looso, M.; Kaulich, M.; Offermanns, S.; Fleming, I.: Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease. CARDIOVASCULAR RESEARCH (2026)