Publications

Cartura, M.; Aliraj, B.; Szymanski, W.; Park, C.; Ferrario, G.; Rezende, F.; Guven, B.; Bleckwehl, T.; Sachs, N.; Magdefessel, L. et al.; Dimmeler, S.; Muller, O. J.; Jo, H.; Offermanns, S.; Hayat, S.; Brandes, R. P.; Munch, C.; Graumann, J.; Weigert, A.; Fleming, I.; Siragusa, M.: Immunomodulatory endothelial cells contribute to T-cell recruitment and activation via antigen presentation on MHC II. CARDIOVASCULAR RESEARCH 122 (12), pp. 1672 - 1687 (2026)

Kwon, J.; Persechino, M.; Shao, J.; Shamsara, J.; Spitznagel, B.; Salwig, I.; Sanda, M.; Offermanns, S.; Kolb, P.; Wettschureck, N.: Small molecule inhibitor of orphan GPCR dimerization improves host defense and blood pressure control in mice. JOURNAL OF CLINICAL INVESTIGATION 136 (15), e203162 (2026)

Mansouri, S.; Hesami, G.; Ambikan, A.; Karger, A.; Klatt, S.; Neogi, U.; Kurakula, K. B.; Aliraj, B.; Miller, A.; Petrova, B. et al.; Sanda, M.; Sirait-Fischer, E.; Guenther, S.; Kuenne, C.; Ruppert, C.; Alkoudmani, I.; Gattenlohner, S.; Zukunft, S.; Fleming, I.; Haschemi, A.; Stiewe, T.; Grimminger, F.; Reck, M.; Weigert, A.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: IRG1/itaconate rewires macrophage and lung tumor metabolism through G6PD inhibition. CELL METABOLISM 38 (7), pp. 1460 - 1477 (2026)

Raheja, M.; Guven, B.; Szymanski, W.; Gunther, S.; Kuenne, C.; Rakultsev, V.; Segarra, M.; Bozkurt, S.; Munch, C.; Kaulich, M. et al.; Graumann, J.; Fleming, I.; Siragusa, M.: A microprotein encoded by FERMT3 modulates endothelial cell protein catabolism and induces cell cycle arrest and senescence. CELL COMMUNICATION AND SIGNALING 24 (1), 372 (2026)

Siragusa, M.; Graumann, J.; Kuenne, C.; Gunther, S.; Jeratsch, S.; Guven, B.; Susser, S.; Talyan, S.; Bezuneh, B.; Matthess, Y. et al.; Cartura, M.; Zhou, X.; Cho, H.; Sachs, N.; Maegdefessel, L.; Muller, O. J.; Troidl, C.; Nef, H. M.; Looso, M.; Kaulich, M.; Offermanns, S.; Fleming, I.: Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease. CARDIOVASCULAR RESEARCH (2026)

Aljuhani, R.; Benicky, J.; Panigrahi, A.; Mukherjee, P.; Sanda, M.; Zhu, S.; Novakova, Z.; Pomin, V. H.; Liu, J.; Davidson, B. et al.; Barinka, C.; Goldman, R.: Production and inhibition of human Heparan 6-O-Endosulfatase SULF1. GLYCOBIOLOGY 35 (12), cwaf059 (2025)

Neogi, U.; Ambikan, A. T.; Turkowski, K.; Schneider, M. A.; Beutgen, V. M.; Graumann, J.; Winter, H.; Bartkuhn, M.; Seeger, W.; Pullamsetti, S. S. et al.; Savai, R.: Plasma proteomic profiling and molecular clustering reveal immune-defined prognostic subtypes in lung adenocarcinoma. INTERNATIONAL JOURNAL OF CANCER (2025)

Roquid, K. A.; Vucetic, A.; Dyukova, E.; Hanssen , M. J.; Cho, H.; Bonnavion, R.; Mattonet, K.; Looso, M.; Sanda, M.; Strilic, B. et al.; Offermanns, S.: Lung endothelial PEAR1 induces tumor cell dormancy. MOLECULAR CANCER 24 (1), 278 (2025)

Cho, H.; Lai, C.-C.; Bonnavion, R.; Alnouri, M. W.; Wang, S.; Roquid, K. A.; Kawase, H.; Campos, D.; Chen, M.; Weinstein, L. S. et al.; Martinez, A.; Looso, M.; Sanda, M.; Offermanns, S.: Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes. SCIENCE 387 (6734), pp. 674 - 682 (2025)

Cho, H.; Lai, C.-C.; Bonnavion, R.; Alnouri, M. W.; Wang, S.; Roquid, K. A.; Kawase, H.; Campos, D.; Chen, M.; Weinstein, L. S. et al.; Martinez, A.; Looso, M.; Sanda, M.; Offermanns, S.: Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes. SCIENCE 387 (6734), pp. 674 - 682 (2025)

Cordero, J.; Swaminathan, G.; Rogel-Ayala, D. G.; Rubio, K.; Elsherbiny, A.; Mahmood, S.; Szymanski, W.; Graumann, J.; Braun, T.; Guenther, S. et al.; Dobreva, G.; Barreto, G.: Nuclear microRNA 9 mediates G-quadruplex formation and 3D genome organization during TGF-β-induced transcription. NATURE COMMUNICATIONS 15 (1), 10711 (2024)

Xu, Y.; Gehlot, R.; Capon, S. J.; Albu, P. M.; Gretz, J.; Bloomekatz, J.; Mattonet, K.; Vucicevic, D.; Talyan, S.; Kikhi, K. et al.; Guenther, S.; Looso, M.; Firulli, B. A.; Sanda, M.; Firulli, A. B.; Lacadie, S. A.; Yelon, D.; Stainier, D. Y. R.: PDGFRA is a conserved HAND2 effector during early cardiac development. NATURE CARDIOVASCULAR RESEARCH 3 (12) (2024)

Xu, Y.; Gehlot, R.; Capon, S. J.; Albu, M.; Gretz, J.; Bloomekatz, J.; Mattonet, K.; Vucicevic, D.; Talyan, S.; Kikhi, K. et al.; Guenther, S.; Looso, M.; Firulli, B. A.; Sanda, M.; Firulli, A. B.; Lacadie, S. A.; Yelon, D.; Stainier, D. Y. R.: PDGFRA is a conserved HAND2 effector during early cardiac development. NATURE CARDIOVASCULAR RESEARCH 3 (12) (2024)

Hebchen, D. M.; Schader, T.; Spaeth, M.; Mueller, N.; Graumann, J.; Schroeder, K.: NoxO1 regulates EGFR signaling by its interaction with Erbin. REDOX BIOLOGY 77, 103396 (2024)

Maroli, G.; Scha, A.; Guenther, S.; -Gonzalez, C. G.; Rupp, S.; Schlierbach, H.; Chen, Y.; Graumann, J.; Wietelmann, A.; Kim, J. et al.; Braun, T.: Inhibition of autophagy prevents cardiac dysfunction at early stages of cardiomyopathy in Bag3-deficient hearts. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 193, pp. 53 - 66 (2024)

Brichkina, A.; Ems, M.; Suezov, R.; Singh, R.; Lutz, V.; Picard, F. S. R.; Nist, A.; Stiewe, T.; Graumann, J.; Daude, M. et al.; Diederich, W. E.; Finkernagel, F.; Chung, H.-R.; Bartsch, D. K.; Roth, K.; Keber, C.; Denkert, C.; Huber, M.; Gress, T. M.; Lauth, M.: DYRK1B blockade promotes tumoricidal macrophage activity in pancreatic cancer. GUT (2024)

Neuhaus, F.; Lieber, S.; Shinkevich, V.; Steitz, A. M.; Raifer, H.; Roth, K.; Finkernagel, F.; Worzfeld, T.; Burchert, A.; Keber, C. et al.; Nist, A.; Stiewe, T.; Reinartz, S.; Beutgen, V. M.; Graumann, J.; Pauck, K.; Garn, H.; Gaida, M.; Mueller, R.; Huber, M.: Reciprocal crosstalk between Th17 and mesothelial cells promotes metastasis-associated adhesion of ovarian cancer cells. CLINICAL AND TRANSLATIONAL MEDICINE 14 (4), e1604 (2024)

Girgis, M.; Petruncio, G.; Russo, P.; Peyton, S.; Paige, M.; Campos, D.; Sanda, M.: Analysis of N- and O-linked site-specific glycosylation by ion mobility mass spectrometry: State of the art and future directions. PROTEOMICS (2024)

Deutschmeyer, V. E.; Schlaudraff, N. A.; Walesch, S. K.; Moyer, J.; Sokol, A. M.; Graumann, J.; Meissner, W.; Schneider, M.; Muley, T.; Helmbold, P. et al.; Schwinn, M.; Richter, A. M.; Schmitz, M. L.; Dammann, R. H.: SIAH3 is frequently epigenetically silenced in cancer and regulates mitochondrial metabolism. INTERNATIONAL JOURNAL OF CANCER (2024)

Campos, D.; Girgis, M.; Yang , Q.; Zong, G.; Goldman, R.; Wang , L.-X.; Sanda, M.: "Ghost" Fragment Ions in Structure and Site-Specific Glycoproteomics Analysis. ANALYTICAL CHEMISTRY (Volume 95, Issue 27), pp. 10145 - 10148 (2023)