Journal Article (66)

2025
Journal Article
Franck, L.; Hahnefeld, L.; Valek, L.; Klatt-Schreiner, K.; Wilken-Schmitz, A.; Alnouri, M. W.; Trautmann, S.; Weyer, M.-P.; Thomas, D.; Gurke, R. et al.; Offermanns, S.; Geisslinger, G.; Tegeder, I.: Elevated hexosylceramides in Parkinson's disease cause gene upregulations in neurons mimicking responses to pathogens. NPJ PARKINSONS DISEASE 11 (1), 268 (2025)
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Eichhorn, M. E.; Niedermaier, B.; Charoentong, P.; Klotz V, L.; Baum, P.; Griffo, R.; Allgaeuer, M.; Stenzinger, A.; Bischoff, H.; Schneider, M. A. et al.; Christopoulos, P.; Haberkorn, U.; Heussel, C.-P.; Savai, R.; Roberti, M. P.; Zoernig, I.; Jaeger, D.; Herth, F.; Thomas, M.; Winter, H.; Eichhorn, F.: Neoadjuvant anti-programmed death-1 immunotherapy by pembrolizumab in resectable non-small cell lung cancer: results of the NEOMUN trial. JOURNAL FOR IMMUNOTHERAPY OF CANCER 13 (8), e011874 (2025)
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Rako, Z. A.; Cekay, M.; Yogeswaran, A.; Yildiz, S.; Arndt, P. F.; Kremer, N.; Schaefer, S.; Janetzko, P.; Thal, B. R.; Mummert, C. M. et al.; Franken, J. K.; Soethe, H.; Werner, H. F.; Dumitrascu, R.; Grimminger, F.; Ghofrani, H. A.; Pullamsetti, S. S.; Seeger, W.; Naeije, R.; Savai, R.; Eul, B.; Tello, K.: Echocardiographic Measure of Right Ventricular-Pulmonary Arterial Coupling Predicts Survival in Lung Cancer. ANNALS OF THE AMERICAN THORACIC SOCIETY 22 (7), pp. 1071 - 1078 (2025)
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Dutzmann, J.; Daniel, J.-M.; Korte, L.; Kloss, F. J.; Knoepp, K.; Kalies, K.; Croce, K. J.; Herbst, T. J.; Huibregtse, B.; Vogt, F. J. et al.; Offermanns, S.; Bauersachs, J.; Sedding, D. G.: Adventitial Fibroblasts Release Interleukin 6 After Vascular Injury and Induce Smooth Muscle Cell Proliferation and Neointima Formation. JOURNAL OF THE AMERICAN HEART ASSOCIATION 14 (14), e040143 (2025)
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Shao, J.; Kwon, J.; Wang, T.; Guenther, S.; Tombor, L. S.; Warwick, T.; Shaheryar, Z.; Brandes, R. P.; Dimmeler, S.; Wenzel, J. et al.; Offermanns, S.; Schwaninger, M.; Wettschureck, N.: Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. NATURE COMMUNICATIONS 16 (1), 6232 (2025)
Journal Article
Jafari, L.; Wiedenroth, C. B.; Kriechbaum, S. D.; Gruen, D.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Spaeth, A. M.; Cherian, A. V.; Troidl, C. et al.; Wilhelm, J.; Keranov, S.; Keller, T.; Kojonazarov, B.; Schermuly, R. T.; Guth, S.; Doerr, O.; Nef, H.; Boehm, M.; Spiekerkoetter, E.; Leszek, P.; Varga, Z. V.; Ferdinandy, P.; Ghofrani, H. A.; Dorfmueller, P.; Weissmann, N.; Hamm, C. W.; Mayer, E.; Seeger, W.; Liebetrau, C.; Pullamsetti, S. S.: Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery. NATURE CARDIOVASCULAR RESEARCH 4 (7) (2025)
Journal Article
Rodriguez-Pulido, M.; Sanz, M. A.; Camacho, L.; Ramos, R.; Saiz, M.: Dicer is cleaved by the Leader protease encoded by foot-and-mouth disease virus to promote infection in mammalian cells. SCIENCE ADVANCES 11 (27), eadt3751 (2025)
Journal Article
Milovanovic, M.; Novkovic, M.; Boskovic, S.; Juez, R. M.; Milicevic, A.; Jasnic, J.; Milosevic, E.; Ilic, B.; Stainier, D. Y. R.; Kojic, S.: Activation of ankrd1a expression marks newly forming myofibers and regulates muscle cell differentiation in adult zebrafish skeletal muscle repair. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 329 (1), pp. C213 - C234 (2025)
Journal Article
Ruiz, V. M. G.; Khabaza, A.; Bauer, R.; Aliraj, B.; Mansouri, S.; Meyer, S. P.; Palmer, M. A.; Winter, H.; V. Klotz, L.; Elewa, M. A. F. et al.; Kur, I. M.; Angioni, C.; Mojaradfar, R.; Hahnefeld, L.; Savai, R.; Fuhrmann, D.; Weigert, A.; Brune, B.: Macrophage fatty acid metabolism under chronic hypoxia shapes γS T cell recruitment via CCL22. ISCIENCE 28 (8), 113025 (2025)
Journal Article
Weipert, K.; Nef, H.; Voss, S.; Hoffmann, J.; Reischauer, S.; Rolf, A.; Troidl, K.; Wietelmann, A.; Hamm, C. W.; Sossalla, S. T. et al.; Troidl, C.: Antagonizing CCR2 With Propagermanium Leads to Altered Distribution of Macrophage Subsets and Favorable Tissue Remodeling After Myocardial Infarction in Mice. CARDIOVASCULAR THERAPEUTICS 2025 (1), 8856808 (2025)
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Capon, S. J.; Maroufidou, A.; Feltes, M.; Xu, Y.; Matharoo, D. K.; Juelich, D.; Holley, S. A.; Farber, S. A.; Stainier, D. Y. R.: A genetic modifier links integrin α5 to the phenotypic variation in fibronectin 1a mutant zebrafish. PLOS GENETICS 21 (6), e1011747 (2025)
Journal Article
Xu, L.; Li, T.; Cao, Y.; He, Y.; Shao, Z.; Liu, S.; Wang, B.; Su, A.; Tian, H.; Li, Y. et al.; Liang, G.; Wang, C.; Shyy, J.; Xiong, Y.; Chen, F.; Yuan, J. X.J.; Liu, J.; Zhou, B.; Wettschureck, N.; Offermanns, S.; Yan, Y.; Yuan, Z.; Wang, S.: PIEZO1 mediates periostin myofibroblast activation and pulmonary fibrosis in mice. JOURNAL OF CLINICAL INVESTIGATION 135 (11), e184158 (2025)
Journal Article
Leko, L.; Simic, D.; Martins, T. V.; da Silva, G. V. L.; Maillet, I.; Savigny, F.; Vuksan, L.; Rodrigues, D. d. M.; Le Bert, M.; Offermanns, S. et al.; Riteau, N.; Togbe, D.; Quesniaux, V. F.; Russo, R. C.; Alves-Filho, J. C.; Ryffel, B.: Butyrate receptor HCAR2/GPR109A controls imiquimod-induced psoriasis-like skin inflammation. JOURNAL OF IMMUNOLOGY (2025)
Journal Article
Liu, H.; Tang, Y.; Singh, A.; Vong, J.; Cordero, J.; Mathes, A.; Gao, R.; Jia, Y.; Garvalov, B. K.; Acker, T. et al.; Poschet, G.; Hell, R.; Schneider, M. A.; Heineke, J.; Wieland, T.; Barreto, G.; Cerwenka, A.; Potente, M.; Bibli, S.-I.; Savai, R.; Dobreva, G.: RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. NATURE COMMUNICATIONS 16 (1), 4929 (2025)
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Dobersch, S.; Yamamoto, N.; Schutter, A.; Cavender, S. M.; Robertson, T. M.; Kartha, N.; Samraj, A. N.; Doron, B.; Poole, L. A.; Wladyka, C. L. et al.; Zhang, A.; Jang, G. H.; Mahalingam, A. H.; Barreto, G.; Raghavan, S.; Narla, G.; Notta, F.; Eisenman, R. N.; Hsieh, A. C.; Kugel, S.: HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity. NATURE COMMUNICATIONS 16 (1), 4866 (2025)
Journal Article
Schmerer, N.; Janga, H.; Aillaud, M.; Hoffmann, J.; Aznaourova, M.; Wende, S.; Steding, H.; Halder, L. D.; Uhl, M.; Boldt, F. et al.; Stiewe, T.; Nist, A.; Jerrentrup, L.; Kirschbaum, A.; Ruppert, C.; Rossbach, O.; Ntini, E.; Marsico, A.; Valasarajan, C.; Backofen, R.; Linne, U.; Pullamsetti, S. S.; Schmeck, B.; Schulte, L. N.: A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages. NATURE COMMUNICATIONS 16 (1), 4733 (2025)
Journal Article
Better, J.; Estiri, M.; Wetstein, M.; Pervizaj-Oruqaj, L.; Malainou, C.; Ogungbemi-Alt, V.; Ferrero, M. R.; Langelage, M.; Kuznetsova, I.; Vazquez-Armendariz, A. I. et al.; Kimmig, L.; Pak, O.; Mansouri, S.; Savai, R.; Wilhelm, J.; Alexopoulos, I.; Sommer, N.; Herold, S.; Matt, U.: Cell type-specific efferocytosis determines functional plasticity of alveolar macrophages. SCIENCE IMMUNOLOGY 10 (107), eadl3852 (2025)
Journal Article
Gajawada, P.; Guenther, S.; Rolf, A.; Nabhanizadeh, J.; Savai, R.; Choi, Y.-H.; Richter, M.: Transcriptomic profiling of granuloma in patients with cardiac sarcoidosis. THERANOSTICS 15 (13), pp. 6044 - 6057 (2025)
Journal Article
Constanty, F.; Wu, B.; Wei, K.-H.; Lin, I.-T.; Dallmann, J.; Guenther, S.; Lautenschlaeger, T.; Priya, R.; Lai, S.-L.; Stainier, D. Y. R. et al.; Beisaw, A.: Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration. NATURE COMMUNICATIONS 16 (1), 3823 (2025)
Journal Article
Kosinska, J.; Assmann, J. C.; Inderhees, J.; Mueller-Fielitz, H.; Haendler, K.; Geisler, S.; Kuenstner, A.; Busch, H.; Worthmann, A.; Heeren, J. et al.; Sadik, C. D.; Gunzer, M.; Prevot, V.; Nogueiras, R.; Hirose, M.; Spielmann, M.; Offermanns, S.; Wettschureck, N.; Schwaninger, M.: Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR2. ELIFE 14, e98970 (2025)
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