Publications of Chanil Valasarajan

Zierden, M.; Berghausen, E. M.; Gnatzy-Feik, L.; Millarg, C.; Picard, F. S. R.; Kiljan, M.; Geissen, S.; Polykratis, A.; Zimmermann, L.; Nies, R. J. et al.; Pasparakis, M.; Baldus, S.; Valasarajan, C.; Pullamsetti, S. S.; Winkels, H.; Vantler, M.; Rosenkranz, S.: Hematopoietic PI3KS deficiency aggravates murine atherosclerosis through impairment of Tregs. JCI INSIGHT 9 (22), e155626 (2024)

Khassafi, F.; Chelladurai, P.; Valasarajan, C.; Nayakanti, S. R.; Martineau, S.; Sommer, N.; Yokokawa, T.; Boucherat, O.; Kamal, A.; Kiely, D. G. et al.; Swift, A. J.; Alabed, S.; Omura, J.; Breuils-Bonnet, S.; Kuenne, C.; Potus, F.; Guenther, S.; Savai, R.; Seeger, W.; Looso, M.; Zaugg, J. B.; Tello, K.; Provencher, S.; Bonnet, S.; Pullamsetti, S. S.: Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. NATURE CARDIOVASCULAR RESEARCH 2 (10), pp. 917 - + (2023)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Chelladurai, P.; Kuenne, C.; Bourgeois, A.; Guenther, S.; Valasarajan, C.; Cherian V, A.; Rottier, R. J.; Romanet, C.; Weigert, A.; Boucherat, O. et al.; Eichstaedt, C. A.; Ruppert, C.; Guenther, A.; Braun, T.; Looso, M.; Savai, R.; Seeger, W.; Bauer, U.-M.; Bonnet, S.; Pullamsetti, S. S.: Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension. SCIENCE TRANSLATIONAL MEDICINE 14 (648), eabe5407 (2022)

Zehendner, C. M.; Valasarajan, C.; Werner, A.; Boeckel, J.-N.; Bischoff, F. C.; John, D.; Weirick, T.; Glaser, S. F.; Rossbach, O.; Jae, N. et al.; Demolli, S.; Khassafi, F.; Yuan, K.; Perez, V. A. d. J.; Michalik, K. M.; Chen, W.; Seeger, W.; Guenther, A.; Wasnick, R. M.; Uchida, S.; Zeiher, A. M.; Dimmeler, S.; Pullamsetti, S. S.: Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFR beta. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 202 (10), pp. 1445 - 1457 (2020)

Dabral, S.; Muecke, C.; Valasarajan, C.; Schmoranzer, M.; Wietelmann, A.; Semenza, G. L.; Meister, M.; Muley, T.; Seeger-Nukpezah, T.; Samakovlis, C. et al.; Weissmann, N.; Grimminger, F.; Seeger, W.; Savai, R.; Pullamsetti, S. S.: A RASSF1A-HIF1 alpha loop drives Warburg effect in cancer and pulmonary hypertension. NATURE COMMUNICATIONS 10, 2130 (2019)

Leisegang, M. S.; Fork, C.; Josipovic, I.; Richler, F.; Preussner, J.; Millers, M. J.; Epah, J.; Hofmann, P.; Anther, S.; Valasarajan, C. et al.; Moll, F.; Heidler, J.; Ponomareva, Y.; Maegdefesser, L.; Uchida, S.; Kunne, C.; Sleilos, K.; Schermuly, R. T.; Weissmann, N.; Devraj, K.; Wittig, I.; Boon, R. A.; Dimmeler, S.; Pullamsetti, S. S.; Looso, M.; Miller Jr., F. J.; Brandes, R. P.: LncRNA MANTIS facilitates endothelial angiogenic function. ACTA PHYSIOLOGICA 219, p. 58 - 58 (2017)

Leisegang, M. S.; Fork, C.; Josipovic, I.; Richter, F. M.; Preussner, J.; Hu, J.; Miller, M. J.; Epah, J.; Hofmann, P.; Guenther, S. et al.; Moll, F.; Valasarajan, C.; Heidler, J.; Ponomareva, Y.; Freiman, T. M.; Maegdefessel, L.; Plate, K. H.; Mittelbronn, M.; Uchida, S.; Kuenne, C.; Stellos, K.; Schermuly, R. T.; Weissmann, N.; Devraj, K.; Wittig, I.; Boon, R. A.; Dimmeler, S.; Pullamsetti, S. S.; Looso, M.; Miller Jr., F. J.; Brandes, R. P.: Long Noncoding RNA MANTIS Facilitates Endothelial Angiogenic Function. CIRCULATION 136 (1), pp. 65 - + (2017)

Dabral, S.; Muecke, C.; Schmoranzer, M.; Valsarajan, C.; Wietelmann, A.; Savai, R.; Seeger, W.; Dammann, R.; Pullamsetti, S. S.: Rassf1a Regulates Ros-Hif Axis In Hypoxia Driven Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 193 (2016)

Dabral, S.; Muecke, C.; Schmoranzer, M.; Valsarajan, C.; Wietelmann, A.; Savai, R.; Seeger, W.; Dammann, R.; Pullamsetti, S. S.: Rassf1a Regulates Ros-Hif Axis In Hypoxia Driven Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 193 (2016)