Publications of R. Savai

Journal Article (58)

2018
Journal Article
Sarode, P.; Zheng, X.; Weigert, A.; Tretyn, A.; Guenther, S.; Pullamsetti, S. S.; Grimminger, F.; Seeger, W.; Savai, R.: Reprogramming of Tumor Associated Macrophages by Modulating Wnt beta-Catenin Signalling in Lung Cancer. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)
Journal Article
Turkowski, K.; Haselbauer, T.; Kaduthanam, S.; Sueltmann, H.; Grimminger, F.; Seeger, W.; Savai, R.: Macrophage and Cancer Cell Crosstalk Regulated MicroRNA 147b Plays a Crucial Role in Lung Cancer Progression. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)
2017
Journal Article
Kiehl, S.; Zimmermann, T.; Savai, R.; Pullamsetti, S. S.; Seeger, W.; Bartkuhn, M.; Dammann, R. H.: Epigenetic silencing of downstream genes mediated by tandem orientation in lung cancer. SCIENTIFIC REPORTS 7, 3896 (2017)
Journal Article
Pullamsetti, S. S.; Kojonazarov, B.; Storn, S.; Gall, H.; Salazar, Y.; Wolf, J.; Weigert, A.; El-Nikhely, N.; Ghofrani, H. A.; Krombach, G. A. et al.; Fink, L.; Gattenlohner, S.; Rapp, U. R.; Schermuly, R. T.; Grimminger, F.; Seeger, W.; Savai, R.: Lung cancer-associated pulmonary hypertension: Role of microenvironmental inflammation based on tumor cell-immune cell cross-talk. SCIENCE TRANSLATIONAL MEDICINE 9 (416), eaai9048 (2017)
Journal Article
Pullamsetti, S. S.; Savai, R.: Macrophage Regulation during Vascular Remodeling: Implications for Pulmonary Hypertension Therapy. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY 56 (5), pp. 556 - 558 (2017)
Journal Article
Pullamsettit, S. S.; Savai, R.; Seeger, W.; Goncharova, E. A.: From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics Targeting Cell Growth and Proliferation Signaling Hubs. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 195 (4), pp. 425 - 437 (2017)
Journal Article
Savai, R.; Asafova, A.; Zheng, X.; Schmall, A.; Weigert, A.; Pullamsetti, S. S.; Seeger, W.: Circulating Fibrocytes Depletion Results In Reduced Lung Tumor Growth And Metastasis By Modulating Macrophage Phenotype, Angiogenesis And Endothelin System. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 195 (2017)
Journal Article
Weichand, B.; Popp, R.; Dziumbla, S.; Mora, J.; Strack, E.; Elwakeel, E.; Frank, A.-C.; Scholich, K.; Pierre, S.; Syed, S. N. et al.; Olesch, C.; Ringleb, J.; Oeren, B.; Doering, C.; Savai, R.; Jung, M.; von Knethen, A.; Levkau, B.; Fleming, I.; Weigert, A.; Bruene, B.: S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1 beta. JOURNAL OF EXPERIMENTAL MEDICINE 214 (9), pp. 2695 - 2713 (2017)
Journal Article
Zheng, X.; Sarode, P.; Weigert, A.; Guenther, S.; Chelladurai, P.; Pullamsetti, S. S.; Seeger, W.; Savai, R.: Re-Education Of Tumor-Associated Macrophages By Modulating Histone Deacetylases In Lung Cancer. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 195 (2017)
Journal Article
Zheng, X.; Turkowski, K.; Mora, J.; Brne, B.; Seeger, W.; Weigert, A.; Savai, R.: Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy. ONCOTARGET 8 (29), pp. 48436 - 48452 (2017)
2016
Journal Article
Dabral, S.; Muecke, C.; Schmoranzer, M.; Valsarajan, C.; Wietelmann, A.; Savai, R.; Seeger, W.; Dammann, R.; Pullamsetti, S. S.: Rassf1a Regulates Ros-Hif Axis In Hypoxia Driven Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 193 (2016)
Journal Article
Dabral, S.; Muecke, C.; Schmoranzer, M.; Valsarajan, C.; Wietelmann, A.; Savai, R.; Seeger, W.; Dammann, R.; Pullamsetti, S. S.: Rassf1a Regulates Ros-Hif Axis In Hypoxia Driven Pulmonary Hypertension. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 193 (2016)
Journal Article
Dabral, S.; Tian, X.; Kojonazarov, B.; Savai, R.; Ghofrani, H. A.; Weissmann, N.; Florio, M.; Sun, J.; Jonigk, D.; Maegel, L. et al.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Schermuly, R. T.: Notch1 signalling regulates endothelial proliferation and apoptosis in pulmonary arterial hypertension. EUROPEAN RESPIRATORY JOURNAL 48 (4), pp. 1137 - 1149 (2016)
Journal Article
Ghanbari, P.; Wheeler, M.; Stubenvoll, A.; Braun, T.; Savai, R.: The role of emerin in coupling Wnt/beta-catenin signalling to genomic instability in cancer. MOLECULAR BIOLOGY OF THE CELL 27 (2016)
Journal Article
Ghanbari, P.; Wheeler, M.; Stubenvoll, A.; Braun, T.; Savai, R.: The role of emerin in coupling Wnt/beta-catenin signalling to genomic instability in cancer. MOLECULAR BIOLOGY OF THE CELL 27 (2016)
Journal Article
Mehta, A.; Cordero Henriquez, J. D.; Dobersch, S.; Romero-Olmedo, Addi J. (Max Planck Institute for Heart and Lung Research, Lung Cancer Epigenetics), A. J.; Savai, R.; Bodner, J.; Chao, C.-M.; Fink, L.; Guzman-Diaz, E.; Singh, I. et al.; Dobreva, G.; Rapp, U. R.; Guenther, S.; Ilinskaya, O. N.; Bellusci, S.; Dammann, R. H.; Braun, T.; Seeger, W.; Gattenloehner, S.; Tresch, A.; Guenther, A.; Barreto, G.: Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate. EMBO MOLECULAR MEDICINE 8 (12), pp. 1380 - 1389 (2016)
Journal Article
Wanzel, I.; Vischedyk, J. B.; Gittler, M. P.; Gremke, N.; Seiz, J. R.; Hefter, M.; Noack, M.; Savai, R.; Mernberger, M.; Charles, J. P. et al.; Schneikert, J.; Bretz, A. C.; Nist, A.; Stiewe, T.: CRISPR-Cas9-based target validation for p53-reactivating model compounds. NATURE CHEMICAL BIOLOGY 12 (1), pp. 22 - + (2016)
Journal Article
Wanzel, I.; Vischedyk, J. B.; Gittler, M. P.; Gremke, N.; Seiz, J. R.; Hefter, M.; Noack, M.; Savai, R.; Mernberger, M.; Charles, J. P. et al.; Schneikert, J.; Bretz, A. C.; Nist, A.; Stiewe, T.: CRISPR-Cas9-based target validation for p53-reactivating model compounds. NATURE CHEMICAL BIOLOGY 12 (1), pp. 22 - + (2016)
Go to Editor View