Publications of Gergana Dobreva

Liu, H.; Tang, Y.; Singh, A.; Vong, J.; Cordero, J.; Mathes, A.; Gao, R.; Jia, Y.; Garvalov, B. K.; Acker, T. et al.; Poschet, G.; Hell, R.; Schneider, M. A.; Heineke, J.; Wieland, T.; Barreto, G.; Cerwenka, A.; Potente, M.; Bibli, S.-I.; Savai, R.; Dobreva, G.: RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. NATURE COMMUNICATIONS 16 (1), 4929 (2025)

Cordero, J.; Swaminathan, G.; Rogel-Ayala, D. G.; Rubio, K.; Elsherbiny, A.; Mahmood, S.; Szymanski, W.; Graumann, J.; Braun, T.; Guenther, S. et al.; Dobreva, G.; Barreto, G.: Nuclear microRNA 9 mediates G-quadruplex formation and 3D genome organization during TGF-β-induced transcription. NATURE COMMUNICATIONS 15 (1), 10711 (2024)

Cordero, J.; Elsherbiny, A.; Wang, Y.; Juergensen, L.; Constanty, F.; Guenther, S.; Boerries, M.; Heineke, J.; Beisaw, A.; Leuschner, F. et al.; Hassel, D.; Dobreva, G.: Leveraging chromatin state transitions for the identification of regulatory networks orchestrating heart regeneration. NUCLEIC ACIDS RESEARCH (2024)

Hu, J.; Leisegang, M. S.; Looso, M.; Drekolia, M.-K.; Wittig, J.; Mettner, J.; Karantanou, C.; Kyselova, A.; Dumbovic, G.; Li, X. et al.; Li, Y.; Guenther, S.; John, D.; Siragusa, M.; Zukunft, S.; Oo, J.; Wittig, I.; Hille, S.; Weigert, A.; Knapp, S.; Brandes, R. P.; Muller, O. J.; Papapetropoulos, A.; Sigala, F.; Dobreva, G.; Kojonazarov, B.; Fleming, I.; Bibli, S.-I.: Disrupted Binding of Cystathionine gamma-Lyase to p53 Promotes Endothelial Senescence. Circulation research (2023)

Nakajima, H.; Ishikawa, H.; Yamamoto, T.; Chiba, A.; Fukui, H.; Sako, K.; Fukumoto, M.; Mattonet, K.; Kwon, H.-B.; Hui, S. P. et al.; Dobreva, G. D.; Kikuchi, K.; Helker, C. S. M.; Stainier, D. Y. R.; Mochizuki, N.: Endoderm-derived islet1-expressing cells differentiate into endothelial cells to function as the vascular HSPC niche in zebrafish. DEVELOPMENTAL CELL 58 (3), pp. 224 - + (2023)

Jing, Y.; Ren, Y.; Witzel, H. R.; Dobreva, G.: A BMP4-p38 MAPK signaling axis controls ISL1 protein stability and activity during cardiogenesis. STEM CELL REPORTS 16 (8), pp. 1894 - 1905 (2021)

Dobersch, S.; Rubio, K.; Singh, I.; Guenther, S.; Graumann, J.; Cordero, J.; Castillo-Negrete, R.; Huynh, M. B.; Mehta, A.; Braubach, P. et al.; Cabrera-Fuentes, H.; Bernhagen, J.; Chao, C.-M.; Bellusci, S.; Guenther, A.; Preissner, K. T.; Kugel, S.; Dobreva, G.; Wygrecka, M.; Braun, T.; Papy-Garcia, D.; Barreto, G.: Positioning of nucleosomes containing gamma-H2AX precedes active DNA demethylation and transcription initiation. NATURE COMMUNICATIONS 12 (1), 1072 (2021)

Chelladurai, P.; Dabral, S.; Basineni, S. R.; Chen, C.-N.; Schmoranzer, M.; Bender, N.; Feld, C.; Noetzold, R. R.; Dobreva, G.; Wilhelm, J. et al.; Jungblut, B.; Zhao, L.; Bauer, U.-M.; Seeger, W.; Pullamsetti, S. S.: Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension. SCIENTIFIC REPORTS 10 (1), 12864 (2020)

Gao, R.; Liang, X.; Cheedipudi, S.; Cordero, J.; Jiang, X.; Zhang, Q.; Caputo, L.; Guenther, S.; Kuenne, C.; Ren, Y. et al.; Bhattacharya, S.; Yuan, X.; Barreto, G.; Chen, Y.; Braun, T.; Evans, S. M.; Sun, Y.; Dobreva, G.: Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate. CELL RESEARCH 29 (6), pp. 486 - 501 (2019)

Jia, Y.; Vong, J. S.-L.; Asafova, A.; Garvalov, B. K.; Caputo, L.; Cordero, J.; Singh, A.; Boettger, T.; Guenther, S.; Fink, L. et al.; Acker, T.; Barreto, G.; Seeger, W.; Braun, T.; Savai, R.; Dobreva, G.: Lamin B1 loss promotes lung cancer development and metastasis by epigenetic derepression of RET. JOURNAL OF EXPERIMENTAL MEDICINE 216 (6), pp. 1377 - 1395 (2019)

Rubio, K.; Singh, I.; Dobersch, S.; Sarvari, P.; Guenther, S.; Cordero, J.; Mehta, A.; Wujak, L.; Cabrera-Fuentes, H.; Chao, C.-M. et al.; Braubach, P.; Bellusci, S.; Seeger, W.; Guenther, A.; Preissner, K. T.; Wygrecka, M.; Savai, R.; Papy-Garcia, D.; Dobreva, G.; Heikenwalder, M.; Savai-Pullamsetti, S.; Braun, T.; Barreto, G.: Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. NATURE COMMUNICATIONS 10, 2229 (2019)

Singh, I.; Contreras, A.; Cordero, J.; Rubio, K.; Dobersch, S.; Guenther, S.; Jeratsch, S.; Mehta, A.; Krueger, M.; Graumann, J. et al.; Seeger, W.; Dobreva, G.; Braun, T.; Barreto, G.: MiCEE is a ncRNA-protein complex that mediates epigenetic silencing and nucleolar organization. NATURE GENETICS 50 (7), pp. 990 - + (2018)

Yuan, X.; Qi, H.; Li, X.; Wu, F.; Fang, J.; Bober, E.; Dobreva, G.; Zhou, Y.; Braun, T.: Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. JOURNAL OF CLINICAL INVESTIGATION 127 (6), pp. 2235 - 2248 (2017)

Mehta, A.; Cordero Henriquez, J. D.; Dobersch, S.; Romero-Olmedo, Addi J. (Max Planck Institute for Heart and Lung Research, Lung Cancer Epigenetics), A. J.; Savai, R.; Bodner, J.; Chao, C.-M.; Fink, L.; Guzman-Diaz, E.; Singh, I. et al.; Dobreva, G.; Rapp, U. R.; Guenther, S.; Ilinskaya, O. N.; Bellusci, S.; Dammann, R. H.; Braun, T.; Seeger, W.; Gattenloehner, S.; Tresch, A.; Guenther, A.; Barreto, G.: Non-invasive lung cancer diagnosis by detection of GATA6 and NKX2-1 isoforms in exhaled breath condensate. EMBO MOLECULAR MEDICINE 8 (12), pp. 1380 - 1389 (2016)