Publications of Stefan Gunther

Wittig, J.; Xu, R.; Lagos, F. D.; Drekolia, M.-K.; Zhang, B.; Theodorou, I.; Chen, Y.; Du, Y.; Gupta, L.; Hanyu, C. et al.; Yuanyuan, L.; Bo, C.; Gunther, S.; Wittig, I.; Ola, R.; Hu, J.; Bibli, S.-I.: Persulfidation alters gene regulatory programs and promotes endothelial specification. REDOX BIOLOGY 89, 103926 (2026)

Siragusa, M.; Graumann, J.; Kuenne, C.; Gunther, S.; Jeratsch, S.; Guven, B.; Susser, S.; Talyan, S.; Bezuneh, B.; Matthess, Y. et al.; Cartura, M.; Zhou, X.; Cho, H.; Sachs, N.; Maegdefessel, L.; Muller, O. J.; Troidl, C.; Nef, H. M.; Looso, M.; Kaulich, M.; Offermanns, S.; Fleming, I.: Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease. CARDIOVASCULAR RESEARCH (2026)

Kawase, H.; Liu, S.; Kurz, S.; Bengelsdorff, V.; Bonnavion, R.; Jin, Y.-J.; Roquid, K. A.; Cho, H.; Liang, G.; Banicevic, M. et al.; Shiva, N.; Yunes-Leites, P. S.; Gunther, S.; Tombor, L.; Dimmeler, S.; Looso, M.; Mattonet, K.; Wettschureck, N.; Muller, U. C.; Offermanns, S.: Endothelial soluble APP/APLP2 promote heart repair through KIT-mediated angiogenesis. SCIENCE ADVANCES 12 (21), eaeh0301 (2026)

Tarasco, M.; Juan, T.; Alayoubi, Y.; Kulkarni, R.; Schumann, A.; da Silva, A. R.; Albu, M.; Dwari, M.; Dlnija, M.; Gunther, S. et al.; Looso, M.; Stainier, D. Y. R.: Time-resolved single-cell transcriptomics maps zebrafish heart development. CELL REPORTS 45 (4), 117249 (2026)

Malainou, C.; Peteranderl, C.; Ferrero, M. R.; Vazquez-Armendariz, A. I.; Alexopoulos, I.; Franz, K.; Knippenberg, K.; Better, J.; Estiri, M.; Wu, C.-Y. et al.; Schultheis, H.; Bushe, J.; del Rio, M.-L.; Rodriguez-Barbosa, J. I.; Pfeffer, K.; Gunther, S.; Looso, M.; Gruber, A. D.; Vadasz, I.; Matt, U.; Herold, S.: TNF superfamily member 14 drives post-influenza depletion of alveolar macrophages, enabling secondary pneumococcal pneumonia. JOURNAL OF CLINICAL INVESTIGATION 136 (2), e185390 (2026)

Martinez-Mayer, J.; Balakrishnan, M.; Cheung, L. Y.; Gunther, S.; Medan, V.; Stainier, D. Y. R.; Perez-Millan, M. I.: Generation of a prop1 knock-in zebrafish enables single-cell transcriptomics of early pituitary development. ENDOCRINOLOGY 167 (5), bqag043 (2026)

Carpenter, B. J.; Lecacheur, M.; Mangold, Y. N.; Cui, K.; Gunther, S.; Vermunt, M. W.; Dierickx, P.: NAD+ controls circadian rhythmicity during cardiac aging. COMMUNICATIONS BIOLOGY 9 (1), 476 (2026)

Stilz, K. A.; Leonard, V. E.; Rodriguez Morales, D.; Glaser, S.-F.; Larcher, V.; Ruz Jurado, M.; Malacarne, P. F.; Manickam, N.; Tombor, L. S.; Abplanalp, W. T. et al.; Panthel, J.; Kujundzic, H.; Fischer, A.; Schmitz, K.; Muller, O. J.; Hille, S.; Kupatt, C.; Bozoglu, T.; Sami, H.; Ogris, M.; Procida-Kowalski, T.; Bartkuhn, M.; John, D.; Yekelchyk, M.; Schmachtel, T.; Rieger, M.; Pham, M.-D.; Krishnan, J.; Gunther, S.; Brandes, R. P.; Braun, T.; Zeiher, A. M.; Wagner, J. U. G.; Dimmeler, S.: Endothelial ZBTB16: a molecular shield against cardiac aging. EUROPEAN HEART JOURNAL 47 (10), pp. 1186 - 1198 (2026)

Leberzammer, J.; Abplanalp, W. T.; Grikscheit, K.; Solomonidis, E. G.; Glaser, S.-F.; Schuhmacher, B.; Merten, M.; Jeremijev, G.; Wilken-Schmitz, A.; Korth, L. et al.; John, D.; Gunther, S.; Kuenne, C.; Looso, M.; Valasarajan, C.; Benes, V.; Jung, F.; Niehaus, V.; Anton, G.; Stellbrink, C.; Rommele, C.; Gopel, S.; Pullamsetti, S. S.; Vehreschild, J.; Vehreschild, M.; Ciesek, S.; Leistner, D. M.; Zeiher, A. M.; Dimmeler, S.; Cremer, S.: Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by interferon priming in circulating myeloid cells. CARDIOVASCULAR RESEARCH (2026)

Dizdarevic, S.; Wiegandt, R.; Weigert, A.; Stiewe, T.; Eul, B.; Guenther, S.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Looso, M. et al.; Turkowski, K.; Savai, R.: Divergent CD45+ immune landscapes shape the lung tumor microenvironment. FRONTIERS IN IMMUNOLOGY 17, 1765833 (2026)

Srivastava, S.; Gunawan, F.; Vergarajauregui, S.; Gentile, A.; Angeloni, M.; Petersen, S. C.; Gunther, S.; Ferrazzi, F.; Stainier, D. Y. R.; Engel, F. B.: Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation. NATURE COMMUNICATIONS 17 (1), 1484 (2026)

Herrle, N.; Malacarne, P. F.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; Leisegang, M. S.; Sarakpi, T.; Wionski, S. et al.; Lopez, M.; Kader, C.; Teichmann, T.; Drekolia, M.-K.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Gunther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Bibli, S.-I.; Segarra, M.; Acker-Palmer, A.; Wagner, J. U. G.; Wittig, I.; Dimmeler, S.; Schulz, M. H.; Richards, J. B.; Gilsbach, R.; Denton, T. T.; Fleming, I.; Hannibal, L.; Brandes, R. P.; Rezende, F.: The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO JOURNAL 45 (3), pp. 820 - 855 (2026)

Wittig, J.; Xu, R.; Lagos, F. D.; Drekolia, M.-K.; Zhang, B.; Theodorou, I.; Chen, Y.; Du, Y.; Gupta, L.; Hanyu, C. et al.; Yuanyuan, L.; Bo, C.; Gunther, S.; Wittig, I.; Ola, R.; Hu, J.; Bibli, S.-I.: Persulfidation alters gene regulatory programs and promotes endothelial specification. REDOX BIOLOGY 89, 103926 (2026)

Drekolia, M.-K.; Mettner, J.; Wang, D.; Lagos, F. D.; Koch, C.; Hecker, D.; Eresch, J.; Mao, Y.; Bahr, M.; Weichenhan, D. et al.; Cordero, J.; Wittig, J.; Zhang, B.; Cui, H.; Li, X.; Oo, J. A.; Weigert, A.; Siragusa, M.; Klatt, S.; Fleming, I.; Gunther, S.; Looso, M.; Brandes, R. P.; Langer, H. F.; Papapetropoulos, A.; Singhal, M.; Schulz, M. H.; Plass, C.; Heineke, J.; Dobreva, G.; Hu, J.; Bibli, S.-I.: Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation. CELL METABOLISM 38 (1) (2026)

Zhou, X.; Kuenne, C.; Gunther, S.; Wittig, I.; Guven, B.; Boutguetait, D.; Delgado Lagos, F.; Sachs, N.; Maegdefessel, L.; Muller, O. J. et al.; Munch, C.; Offermanns, S.; Fleming, I.; Siragusa, M.: Nuclear eNOS Interacts With and S-Nitrosates ADAR1 to Modulate Type I Interferon Signaling and Endothelial Function. CIRCULATION 152 (25) (2025)

Herrle, N.; Malacarne, P. F.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; Leisegang, M. S.; Sarakpi, T.; Wionski, S. et al.; Lopez, M.; Kader, C.; Teichmann, T.; Drekolia, M.-K.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Gunther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Bibli, S.-I.; Segarra, M.; Acker-Palmer, A.; Wagner, J. U. G.; Wittig, I.; Dimmeler, S.; Schulz, M. H.; Richards, J. B.; Gilsbach, R.; Denton, T. T.; Fleming, I.; Hannibal, L.; Brandes, R. P.; Rezende, F.: The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO JOURNAL (2025)

Heck, C.; Zimmermann-Geller, B.; Haun, S.; Lotfering, F.; Welbrink, P.; Kursammer, D.; Frommer, K. W.; Arnold-Graf, M.; Korb-Pap, A.; Knothe, A. et al.; Schulz, N.; Simianer, S.; Tarner, I.; Hermann, W.; Biehl, C.; Gunther, S.; Steinmeyer, J.; Lips, K. S.; Rickert, M.; Rehart, S.; Muller-Ladner, U.; Neumann, E.: Influence of canstatin on fibroblast-driven hypervascularisation in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES 84 (12), pp. 1968 - 1982 (2025)

Heck, C.; Zimmermann-Geller, B.; Haun, S.; Lotfering, F.; Welbrink, P.; Kursammer, D.; Frommer, K. W.; Arnold-Graf, M.; Korb-Pap, A.; Knothe, A. et al.; Schulz, N.; Simianer, S.; Tarner, I.; Hermann, W.; Biehl, C.; Gunther, S.; Steinmeyer, J.; Lips, K. S.; Rickert, M.; Rehart, S.; Muller-Ladner, U.; Neumann, E.: Influence of canstatin on fibroblast-driven hypervascularisation in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES 84 (12), pp. 1968 - 1982 (2025)

Mukherjee, D.; Larcher, V.; Winter, H.; Sachs, N.; Andriani, F.; Chiesa, M.; Perrucci, G. L.; Rega, S.; Gunther, S.; Kuenne, C. et al.; Martin, J. C.; Gu, Y.; Pelisek, J.; Fischer, A.; Peruzzo, S.; Pizzo, E.; Peterson, K. L.; Dimmeler, S.; Maegdefessel, L.; Cattaneo, P.; Evans, S. M.; Guimaraes-Camboa, N.: Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis. CARDIOVASCULAR RESEARCH (2025)

Huber, L. S.; Merline, R.; Zeng-Brouwers, J.; Vutukuri, R.; Kraus, N.; Ortiz, C.; Guenther, S.; Buhl, E. M.; Hahnefeld, L.; Gurke, R. et al.; Bein, J.; Karimova, M.; Wurzel, P.; Boor, P.; Welsch, C.; Wild, P.; Pfeilschifter, J.; Kogel, D.; Wygrecka, M.; Trebicka, J.; Bartoszewski, R.; Dikic, I.; Schaefer, L.: Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 329 (5), pp. C1360 - C1379 (2025)