Publications of Soni Savai Pullamsetti

Zheng, X.; Weigert, A.; Reu, S.; Guenther, S.; Mansouri, S.; Bassaly, B.; Gattenlohner, S.; Grimminger, F.; Pullamsetti, S. S.; Seeger, W. et al.; Winter, H.; Savai, R.: Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small Cell Lung Carcinoma. CANCER RESEARCH 80 (20), pp. 4414 - 4425 (2020)

Weiss, A.; Boehm, M.; Egemnazarov, B.; Grimminger, F.; Pullamsetti, S. S.; Kwapiszewska, G.; Schermuly, R. T.: Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction. BRITISH JOURNAL OF PHARMACOLOGY (2019)

Dabral, S.; Muecke, C.; Valasarajan, C.; Schmoranzer, M.; Wietelmann, A.; Semenza, G. L.; Meister, M.; Muley, T.; Seeger-Nukpezah, T.; Samakovlis, C. et al.; Weissmann, N.; Grimminger, F.; Seeger, W.; Savai, R.; Pullamsetti, S. S.: A RASSF1A-HIF1 alpha loop drives Warburg effect in cancer and pulmonary hypertension. NATURE COMMUNICATIONS 10, 2130 (2019)

Hu, C.-J.; Zhang, H.; Laux, A.; Pullamsetti, S. S.; Stenmark, K. R.: Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension. JOURNAL OF PHYSIOLOGY-LONDON 597 (4), pp. 1103 - 1119 (2019)

Humbert, M.; Guignabert, C.; Bonnet, S.; Dorfmuller, P.; Klinger, J. R.; Nicolls, M. R.; Olschewski, A. J.; Pullamsetti, S. S.; Schermuly, R. T.; Stenmark, K. R. et al.; Rabinovitch, M.: Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives. EUROPEAN RESPIRATORY JOURNAL 53 (1), 1801887 (2019)

Rubio, K.; Singh, I.; Dobersch, S.; Sarvari, P.; Guenther, S.; Cordero, J.; Mehta, A.; Wujak, L.; Cabrera-Fuentes, H.; Chao, C.-M. et al.; Braubach, P.; Bellusci, S.; Seeger, W.; Guenther, A.; Preissner, K. T.; Wygrecka, M.; Savai, R.; Papy-Garcia, D.; Dobreva, G.; Heikenwalder, M.; Savai-Pullamsetti, S.; Braun, T.; Barreto, G.: Inactivation of nuclear histone deacetylases by EP300 disrupts the MiCEE complex in idiopathic pulmonary fibrosis. NATURE COMMUNICATIONS 10, 2229 (2019)

Spiekerkoetter, E.; Goncharova, E. A.; Guignabert, C.; Stenmark, K.; Kwapiszewska, G.; Rabinovitch, M.; Voelkel, N.; Bogaard, H. J.; Graham, B.; Pullamsetti, S. S. et al.; Kuebler, W. M.: Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure. PULMONARY CIRCULATION 9 (4), 2045894019889775 (2019)

Weiss, A.; Neubauer, M. C.; Yerabolu, D.; Kojonazarov, B.; Schlueter, B. C.; Neubert, L.; Jonigk, D.; Baal, N.; Ruppert, C.; Dorfmuller, P. et al.; Pullamsetti, S. S.; Weissmann, N.; Ghofrani, H.-A.; Grimminger, F.; Seeger, W.; Schermuly, R. T.: Targeting cyclin-dependent kinases for the treatment of pulmonary arterial hypertension. NATURE COMMUNICATIONS 10, 2204 (2019)

Al-Tamari, H. M.; Dabral, S.; Schmall, A.; Sarvari, P.; Ruppert, C.; Paik, J.; DePinho, R. A.; Grimminger, F.; Eickelberg, O.; Guenther, A. et al.; Seeger, W.; Savai, R.; Pullamsetti, S. S.: FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis. EMBO MOLECULAR MEDICINE 10 (2), pp. 276 - 293 (2018)

Bouchard, C.; Sahu, P.; Meixner, M.; Noetzold, R. R.; Rust, M. B.; Kremmer, E.; Feederle, R.; Hart-Smith, G.; Finkernagel, F.; Bartkuhn, M. et al.; Pullamsetti, S. S.; Nist, A.; Stiewe, T.; Philipsen, S.; Bauer, U.-M.: Genomic Location of PRMT6-Dependent H3R2 Methylation Is Linked to the Transcriptional Outcome of Associated Genes. CELL REPORTS 24 (12), pp. 3339 - 3352 (2018)

Dinger, K.; Mohr, J.; Jentgen, V.; Hirani, D. V.; Vohlen, C.; Pullamsetti, S. S.; Doetsch, J.; Odenthal, M.; Alcazar, M. A.: Adipose-Tissue Secretome Induces Bronchial Smooth Muscle Cell Proliferation Via an IL-6/FoxO1 Dependent Mechanism in Offspring of Obese Mice. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)

Josipovic, I.; Pflueger, B.; Fork, C.; Vasconez, A. E.; Oo, J. A.; Hitzel, J.; Seredinski, S.; Gamen, E.; zu Heringdorf, D. M.; Chen, W. et al.; Looso, M.; Pullamsetti, S. S.; Brandes, R. P.; Leisegang, M. S.: Long noncoding RNA LISPR1 is required for S1P signaling and endothelial cell function. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 116, pp. 57 - 68 (2018)

Korfei, M.; Stelmaszek, D.; MacKenzie, B.; Skwarna, S.; Chillappagari, S.; Bach, A. C.; Ruppert, C.; Saito, S.; Mahavadi, P.; Klepetko, W. et al.; Fink, L.; Seeger, W.; Lasky, J. A.; Pullamsetti, S. S.; Kraemer, O. H.; Guenther, A.: Comparison of the antifibrotic effects of the pan-histone deacetylase-inhibitor panobinostat versus the IPF-drug pirfenidone in fibroblasts from patients with idiopathic pulmonary fibrosis. PLOS ONE 13 (11), e0207915 (2018)

Korfei, M.; Stelmaszek, D.; Skwarna, S.; Chillappagari, S.; Bach, A. C.; MacKenzie, B.; Ruppert, C.; Saito, S.; Mahavadi, P.; Klepetko, W. et al.; Fink, L.; Seeger, W.; Lasky, J. A.; Pullamsetti, S. S.; Kraemer, O.; Guenther, A.: Comparison of the Antifibrotic Efficacy of the Pan-Histone Deacetylase-Inhibitor Panobinostat Versus the IPF-Drug Pirfenidone in Fibroblasts from Patients with Idiopathic Pulmonary Fibrosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)

Olschewski, A.; Berghausen, E. M.; Eichstaedt, C. A.; Fleischmann, B. K.; Gruenig, E.; Gruenig, G.; Hansmann, G.; Harbaum, L.; Hennigs, J. K.; Jonigk, D. et al.; Kuebler, W. M.; Kwapiszewska, G.; Pullamsetti, S. S.; Stacher, E.; Weissmann, N.; Wenzel, D.; Schermuly, R. T.: Pathobiology, pathology and genetics of pulmonary hypertension: Update from the Cologne Consensus Conference 2018. INTERNATIONAL JOURNAL OF CARDIOLOGY 272, pp. 4 - 10 (2018)

Pullamsetti, S. S.; Seeger, W.; Savai, R.: Classical IL-6 signaling: a promising therapeutic target for pulmonary arterial hypertension. JOURNAL OF CLINICAL INVESTIGATION 128 (5), pp. 1720 - 1723 (2018)

Sarode, P.; Zheng, X.; Weigert, A.; Tretyn, A.; Guenther, S.; Pullamsetti, S. S.; Grimminger, F.; Seeger, W.; Savai, R.: Reprogramming of Tumor Associated Macrophages by Modulating Wnt beta-Catenin Signalling in Lung Cancer. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)

Sommer, N.; Droege, F.; Gamen, K. E.; Geisthoff, U.; Gall, H.; Tello, K.; Richter, M. J.; Deubner, L. M.; Schmiedel, R.; Hecker, M. et al.; Spiekerkoetter, E.; Wirsching, K.; Seeger, W.; Ghofrani, H. A.; Pullamsetti, S.: Treatment with low-dose tacrolimus inhibits bleeding complications in a patient with hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension. PULMONARY CIRCULATION 9 (2), 2045894018805406 (2018)

Stenmark, K. R.; Hu, C.-J.; Pullamsetti, S. S.: How Many FOXs Are There on The Road to Pulmonary Hypertension? AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 198 (6), pp. 704 - 707 (2018)

Dabral, S.; Pullamsetti, S. S.: Vascular Stiffness and Mechanotransduction: Back in the Limelight. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 196 (4), pp. 527 - 530 (2017)