Publications of Stefan Offermanns

Wang, L.; Chennupati, R.; Jin, Y.-J.; Li, R.; Wang, S.; Guenther, S.; Offermanns, S.: YAP/TAZ Are Required to Suppress Osteogenic Differentiation of Vascular Smooth Muscle Cells. ISCIENCE 23 (12), 101860 (2020)

Nakayama, A.; Albarran-Juarez, J.; Liang, G.; Roquid, K. A.; Iring, A.; Tonack, S.; Chen, M.; Mueller, O. J.; Weinstein, L. S.; Offermanns, S.: Disturbed flow-induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis. JCI INSIGHT 5 (23), e140485 (2020)

Horimatsu, T.; Blomkalns, A. L.; Ogbi, M.; Moses, M.; Kim, D.; Patel, S.; Gilreath, N.; Reid, L.; Benson, T. W.; Pye, J. et al.; Ahmadieh, S.; Thompson, A.; Robbins, N.; Mann, A.; Edgell, A.; Benjamin, S.; Stansfield, B. K.; Huo, Y.; Fulton, D. J.; Agarwal, G.; Singh, N.; Offermanns, S.; Weintraub, N. L.; Kim, H. W.: Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD(+)/nicotinamide. CARDIOVASCULAR RESEARCH 116 (14), pp. 2226 - 2238 (2020)

Wang, L.; Wang, S.; Shi, Y.; Li, R.; Guenther, S.; Ong, Y. T.; Potente, M.; Yuan, Z.; Liu, E.; Offermanns, S.: YAP and TAZ protect against white adipocyte cell death during obesity. NATURE COMMUNICATIONS 11 (1), 5455 (2020)

Blankenbach, K. V.; Claas, R. F.; Aster, N. J.; Spohner, A. K.; Trautmann, S.; Ferreiros, N.; Black, J. L.; Tesmer, J. J. G.; Offermanns, S.; Wieland, T. et al.; Meyer zu Heringdorf, D.: Dissecting G(q/11)-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1. CELLS 9 (10), 2201 (2020)

Kwon, H.-B.; Mackie I, D.; Bonnavion, R.; Le Mercier, A.; Helker, C. S. M.; Son, T.; Guenter, S.; Serafin, D. S.; Kim, K.-W.; Offermanns, S. et al.; Caron, K. M.; Stainier, D. Y. R.: The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE 3 (4), pp. 676 - 689 (2020)

Li, M.; Nishio, S.-y.; Naruse, C.; Riddell, M.; Sapski, S.; Katsuno, T.; Hikita, T.; Mizapourshafiyi, F.; Smith, F. M.; Cooper, L. T. et al.; Lee, M. G.; Asano, M.; Boettger, T.; Krueger, M.; Wietelmann, A.; Graumann, J.; Day, B. W.; Boyd, A. W.; Offermanns, S.; Kitajiri, S.-i.; Usami, S.-i.; Nakayama, M.: Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome. NATURE COMMUNICATIONS 11 (1), 1343 (2020)

Bae, H.; Hong, K. Y.; Lee, C.-k.; Jang, C.; Lee, S.-J.; Choe, K.; Offermanns, S.; He, Y.; Lee, H. J.; Koh, G. Y.: Angiopoietin-2-integrin alpha 5 beta 1 signaling enhances vascular fatty acid transport and prevents ectopic lipid-induced insulin resistance. NATURE COMMUNICATIONS 11 (1) (2020)

Carvalho, J.; Chennupati, R.; Li, R.; Guenther, S.; Kaur, H.; Zhao, W.; Tonack, S.; Kurz, M.; Moesslein, N.; Buenemann, M. et al.; Offermanns, S.; Wettschureck, N.: Orphan G Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling. CIRCULATION 141 (14), pp. 1168 - 1183 (2020)

Khatib-Massalha, E.; Bhattacharya, S.; Massalha, H.; Biram, A.; Golan, K.; Kollet, O.; Kumari, A.; Avemaria, F.; Petrovich-Kopitman, E.; Gur-Cohen, S. et al.; Itkin, T.; Brandenburger, I.; Spiegel, A.; Shulman, Z.; Gerhart-Hines, Z.; Itzkovitz, S.; Gunzer, M.; Offermanns, S.; Alon, R.; Ariel, A.; Lapidot, T.: Lactate released by inflammatory bone marrow neutrophils induces their mobilization via endothelial GPR81 signaling. NATURE COMMUNICATIONS 11 (1), 3547 (2020)

Simmons, J. D.; Peterson, G. J.; Campo, M.; Lohmiller, J.; Skerrett, S. J.; Tunaru, S.; Offermanns, S.; Sherman, D. R.; Hawn, T. R.: Nicotinamide Limits Replication of Mycobacterium tuberculosis and Bacille Calmette-Guerin Within Macrophages. JOURNAL OF INFECTIOUS DISEASES 221 (6), pp. 989 - 999 (2020)

Sreenivasan, K.; Ianni, A.; Kuenne, C.; Strilic, B.; Guenther, S.; Perdiguero, E.; Krueger, M.; Spuler, S.; Offermanns, S.; Gomez-del Arco, P. et al.; Miguel Redondo, J.; Munoz-Canoves, P.; Kim, J.; Braun, T.: Attenuated Epigenetic Suppression of Muscle Stem Cell Necroptosis Is Required for Efficient Regeneration of Dystrophic Muscles. CELL REPORTS 31 (7), UNSP 107652 (2020)

Stanicek, L.; Lozano-Vidal, N.; Bink, D. I.; Hooglugt, A.; Yao, W.; Wittig, I.; van Rijssel, J.; van Buul, J. D.; van Bergen, A.; Klems, A. et al.; Ramms, A. S.; Le Noble, F.; Hofmann, P.; Szulcek, R.; Wang, S.; Offermanns, S.; Ercanoglu, M. S.; Kwon, H.-B.; Stainier, D.; Huveneers, S.; Kurian, L.; Dimmeler, S.; Boon, R. A.: Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function. COMMUNICATIONS BIOLOGY 3 (1), 265 (2020)

Wang, S.; Cao, S.; Arhatte, M.; Li, D.; Shi, Y.; Kurz, S.; Hu, J.; Wang, L.; Shao, J.; Atzberger, A. et al.; Wang, Z.; Wang, C.; Zang, W.; Fleming, I.; Wettschureck, N.; Honore, E.; Offermanns, S.: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. NATURE COMMUNICATIONS 11 (1) (2020)

Wenzel, J.; Hansen, C. E.; Bettoni, C.; Vogt, M. A.; Lembrich, B.; Natsagdorj, R.; Huber, G.; Brands, J.; Schmidt, K.; Assmann, J. C. et al.; Stoelting, I.; Saar, K.; Sedlacik, J.; Fiehler, J.; Ludewig, P.; Wegmann, M.; Feller, N.; Richter, M.; Mueller-Fielitz, H.; Walther, T.; Koenig, G. M.; Kostenis, E.; Raasch, W.; Huebner, N.; Gass, P.; Offermanns, S.; de Wit, C.; Wagner, C. A.; Schwaninger, M.: Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 117 (3), pp. 1753 - 1761 (2020)

Abrantes, H. d. C.; Briquet, M.; Schmuziger, C.; Restivo, G.; Puyal, J.; Rosenberg, N.; Rocker, A.-B.; Offermanns, S.; Chatton, J.-Y.: The Lactate Receptor HCAR1 Modulates Neuronal Network Activity through the Activation of G(alpha) and G(beta gamma) Subunits. JOURNAL OF NEUROSCIENCE 39 (23), pp. 4422 - 4433 (2019)

Chennupati, R.; Wirth, A.; Favre, J.; Li, R.; Bonnavion, R.; Jin, Y.-J.; Wietelmann, A.; Schweda, F.; Wettschureck, N.; Henrion, D. et al.; Offermanns, S.: Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance. ELIFE 8, e49374 (2019)

Der, B.; Molnar, P. J.; Ruisanchez, E.; Orsy, P.; Kerek, M.; Farago, B.; Nyirady, P.; Offermanns, S.; Benyo, Z.: NK2 receptor-mediated detrusor muscle contraction involves G(q/11)-dependent activation of voltage-dependent Ca2+ channels and the RhoA-Rho kinase pathway. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 317 (5), pp. F1154 - F1163 (2019)

Erdogmus, S.; Storch, U.; Danner, L.; Becker, J.; Winter, M.; Ziegler, N.; Wirth, A.; Offermanns, S.; Hoffmann, C.; Gudermann, T. et al.; Mederos y Schnitzler, M.: Helix 8 is the essential structural motif of mechanosensitive GPCRs. NATURE COMMUNICATIONS 10, 5784 (2019)

Helker, C. S. M.; Mullapudi, S.-T.; Mueller, L. M.; Preussner, J.; Tunaru, S.; Skog, O.; Kwon, H.-B.; Kreuder, F.; Lancman, J. J.; Bonnavion, R. et al.; Dong, P. D. S.; Looso, M.; Offermanns, S.; Korsgren, O.; Spagnoli, F. M.; Stainier, D. Y. R.: A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development. DEVELOPMENT 146 (14), UNSP dev172569 (2019)