Publications of Jeonghyeon Kwon

Kwon, J.; Persechino, M.; Shao, J.; Shamsara, J.; Spitznagel, B.; Salwig, I.; Sanda, M.; Offermanns, S.; Kolb, P.; Wettschureck, N.: Small molecule inhibitor of orphan GPCR dimerization improves host defense and blood pressure control in mice. JOURNAL OF CLINICAL INVESTIGATION 136 (15), e203162 (2026)

Shiva, N.; Kawase, H.; Einsiedel, J.; Kwon, J.; Kumar, S.; Shao, J.; Du, Z.; Kubin, N.; Shimari, M.; Gunther, S. et al.; Li, T.; Dierickx, P.; Sossalla, S.; Offermanns, S.; Gmeiner, P.; Wettschureck, N.: Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models. SCIENCE TRANSLATIONAL MEDICINE 18 (856), eaea9877 (2026)

Shao, J.; Kwon, J.; Wang, T.; Guenther, S.; Tombor, L. S.; Warwick, T.; Shaheryar, Z.; Brandes, R. P.; Dimmeler, S.; Wenzel, J. et al.; Offermanns, S.; Schwaninger, M.; Wettschureck, N.: Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. NATURE COMMUNICATIONS 16 (1), 6232 (2025)

Kwon, J.; Haruya, K.; Mattonet, K.; Guenther, S.; Hahnefeld, L.; Shamsara, J.; Heering, J.; Kurz, M.; Kirchhofer, S.; Krasel, C. et al.; Ulrich, M.; Persechino, M.; Murthy, S.; Orlandi, C.; Sadik, C. D.; Geisslinger, G.; Buenemann, M.; Kolb, P.; Offermanns, S.; Wettschureck, N.: Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling. NATURE COMMUNICATIONS 16 (1), 1448 (2025)

Alnouri, M. W.; Roquid, K. A.; Bonnavion, R.; Cho, H.; Heering, J.; Kwon, J.; Jaeger, Y.; Wang, S.; Guenther, S.; Wettschureck, N. et al.; Geisslingerb, G.; Gurke, R.; Mueller, C. E.; Proschak, E.; Offermanns, S.: SPMs exert anti- inflammatory and pro- resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 121 (41), e2407130121 (2024)

Tamiato, A.; Tombor, L. S.; Fischer, A.; Muhly-Reinholz, M.; Vanicek, L. R.; Togru, B. N.; Neitz, J.; Glaser, S. F.; Merten, M.; Morales, D. R. et al.; Kwon, J.; Klatt, S.; Schumacher, B.; Guenther, S.; Abplanalp, W. T.; John, D.; Fleming, I.; Wettschureck, N.; Dimmeler, S.; Luxaen, G.: Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis. CIRCULATION RESEARCH 134 (10), pp. 1240 - 1255 (2024)