Publications of Mario Looso

Hu, J.; Leisegang, M. S.; Looso, M.; Drekolia, M.-K.; Wittig, J.; Mettner, J.; Karantanou, C.; Kyselova, A.; Dumbovic, G.; Li, X. et al.; Li, Y.; Guenther, S.; John, D.; Siragusa, M.; Zukunft, S.; Oo, J.; Wittig, I.; Hille, S.; Weigert, A.; Knapp, S.; Brandes, R. P.; Muller, O. J.; Papapetropoulos, A.; Sigala, F.; Dobreva, G.; Kojonazarov, B.; Fleming, I.; Bibli, S.-I.: Disrupted Binding of Cystathionine gamma-Lyase to p53 Promotes Endothelial Senescence. Circulation research (2023)

Li, X.; Wu, F.; Guenther, S.; Looso, M.; Kuenne, C.; Zhang, T.; Wiesnet, M.; Klatt, S.; Zukunft, S.; Fleming, I. et al.; Poschet, G.; Wietelmann, A.; Atzberger, A.; Potente, M.; Yuan, X.; Braun, T.: Inhibition of fatty acid oxidation enables heart regeneration in adult mice. NATURE (2023)

Khassafi, F.; Chelladurai, P.; Valasarajan, C.; Nayakanti, S. R.; Martineau, S.; Sommer, N.; Yokokawa, T.; Boucherat, O.; Kamal, A.; Kiely, D. G. et al.; Swift, A. J.; Alabed, S.; Omura, J.; Breuils-Bonnet, S.; Kuenne, C.; Potus, F.; Guenther, S.; Savai, R.; Seeger, W.; Looso, M.; Zaugg, J. B.; Tello, K.; Provencher, S.; Bonnet, S.; Pullamsetti, S. S.: Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. NATURE CARDIOVASCULAR RESEARCH 2 (10), pp. 917 - + (2023)

Nayakanti, S. R.; Friedrich, A.; Sarode, P.; Jafari, L.; Maroli, G.; Boehm, M.; Bourgeois, A.; Grobs, Y.; Khassafi, F.; Kuenne, C. et al.; Guenther, S.; Dabral, S.; Wilhelm, J.; Weiss, A.; Wietelmann, A.; Kojonazarov, B.; Janssen, W.; Looso, M.; de Man, F.; Provencher, S.; Tello, K.; Seeger, W.; Bonnet, S.; Savai, R.; Schermuly, R.; Pullamsetti, S. S.: Targeting Wnt-ss-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling. CIRCULATION RESEARCH 132 (11), pp. 1468 - 1485 (2023)

Boonsanay, B.; Mosa, M. H.; Looso, M.; Weichenhan, D.; Ceteci, F.; Pudelko, L.; Lechel, A.; Michel, C. S.; Kuenne, C.; Farin, H. F. et al.; Plass, C.; Greten, F. R.: Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression. GASTROENTEROLOGY 164 (2), pp. 214 - 227 (2023)

Wu, F.; Li, X.; Looso, M.; Liu, H.; Ding, D.; Guenther, S.; Kuenne, C.; Liu, S.; Weissmann, N.; Boettger, T. et al.; Atzberger, A.; Kolahian, S.; Renz, H.; Offermanns, S.; Gaertner, U.; Potente, M.; Zhou, Y.; Yuan, X.; Braun, T.: Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. NATURE GENETICS (2023; 55(1)), pp. 100 - 111 (2023)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Drekolia, M.-K.; Talyan, S.; Emidio, R. C.; Boon, R. A.; Guenther, S.; Looso, M.; Dumbovic, G.; Bibli, S.-I.: Unravelling the impact of aging on the human endothelial lncRNA transcriptome. FRONTIERS IN GENETICS 13, 1035380 (2022)

Kuhnert, S.; Mansouri, S.; Rieger, M. A.; Savai, R.; Avci, E.; Diaz-Pina, G.; Padmasekar, M.; Looso, M.; Hadzic, S.; Acker, T. et al.; Klatt, S.; Wilhelm, J.; Fleming, I.; Sommer, N.; Weissmann, N.; Vogelmeier, C.; Bals, R.; Zeiher, A.; Dimmeler, S.; Seeger, W.; Pullamsetti, S. S.: Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD. CELLS 11 (13), 2121 (2022)

Ustjanzew, A.; Preussner, J.; Bentsen, M.; Kuenne, C.; Looso, M.: i2dash: Creation of Flexible, Interactive, and Web-based Dashboards for Visualization of Omics Data. GENOMICS PROTEOMICS & BIOINFORMATICS 20 (3), pp. 568 - 577 (2022)

Chelladurai, P.; Kuenne, C.; Bourgeois, A.; Guenther, S.; Valasarajan, C.; Cherian V, A.; Rottier, R. J.; Romanet, C.; Weigert, A.; Boucherat, O. et al.; Eichstaedt, C. A.; Ruppert, C.; Guenther, A.; Braun, T.; Looso, M.; Savai, R.; Seeger, W.; Bauer, U.-M.; Bonnet, S.; Pullamsetti, S. S.: Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension. SCIENCE TRANSLATIONAL MEDICINE 14 (648), eabe5407 (2022)

Bentsen, M.; Heger, V.; Schultheis, H.; Kuenne, C.; Looso, M.: TF-COMB - Discovering grammar of transcription factor binding sites. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL 20, pp. 4040 - 4051 (2022)

Allanki, S.; Strilic, B.; Scheinberger, L.; Onderwater, Y. L.; Marks, A.; Guenther, S.; Preussner, J.; Kikhi, K.; Looso, M.; Stainier, D. Y. R. et al.; Reischauer, S.: Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration. SCIENCE ADVANCES 7 (37), eabg6497 (2021)

Bibli, S.-I.; Hu, J.; Looso, M.; Weigert, A.; Ratiu, C.; Wittig, J.; Drekolia, M. K.; Tombor, L.; Randriamboavonjy, V.; Leisegang, M. S. et al.; Goymann, P.; Lagos, F. D.; Fisslthaler, B.; Zukunft, S.; Kyselova, A.; Justo, A. F. O.; Heidler, J.; Tsilimigras, D.; Brandes, R. P.; Dimmeler, S.; Papapetropoulos, A.; Knapp, S.; Offermanns, S.; Wittig, I.; Nishimura, S. L.; Sigala, F.; Fleming, I.: Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function. CIRCULATION 143 (9), pp. 935 - 948 (2021)

Bibli, S.-I.; Hu, J.; Looso, M.; Weigert, A.; Ratiu, C.; Wittig, J.; Drekolia, M. K.; Tombor, L.; Randriamboavonjy, V.; Leisegang, M. S. et al.; Goymann, P.; Lagos, F. D.; Fisslthaler, B.; Zukunft, S.; Kyselova, A.; Justo, A. F. O.; Heidler, J.; Tsilimigras, D.; Brandes, R. P.; Dimmeler, S.; Papapetropoulos, A.; Knapp, S.; Offermanns, S.; Wittig, I.; Nishimura, S. L.; Sigala, F.; Fleming, I.: Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function. CIRCULATION 143 (9), pp. 935 - 948 (2021)

Tombor, L. S.; John, D.; Glaser, S. F.; Luxan, G.; Forte, E.; Furtado, M.; Rosenthal, N.; Baumgarten, N.; Schulz, M. H.; Wittig, J. et al.; Rogg, E.-M.; Manavski, Y.; Fischer, A.; Muhly-Reinholz, M.; Klee, K.; Looso, M.; Selignow, C.; Acker, T.; Bibli, S.-I.; Fleming, I.; Patrick, R.; Harvey, R. P.; Abplanalp, W. T.; Dimmeler, S.: Single cell sequencing reveals endothelial plasticity with transient mesenchymal activation after myocardial infarction. NATURE COMMUNICATIONS 12 (1), 681 (2021)

Bhagwat, A. M.; Graumann, J.; Wiegandt, R.; Bentsen, M.; Welker, J.; Kuenne, C.; Preussner, J.; Braun, T.; Looso, M.: multicrispr: gRNA design for prime editing and parallel targeting of thousands of targets. LIFE SCIENCE ALLIANCE 3 (11), e202000757 (2020)

Beisaw, A.; Kuenne, C.; Guenther, S.; Dallmann, J.; Wu, C.-C.; Bentsen, M.; Looso, M.; Stainier, D. Y. R.: AP-1 Contributes to Chromatin Accessibility to Promote Sarcomere Disassembly and Cardiomyocyte Protrusion During Zebrafish Heart Regeneration. CIRCULATION RESEARCH 126 (12), pp. 1760 - 1778 (2020)

Bentsen, M.; Goymann, P.; Schultheis, H.; Klee, K.; Petrova, A.; Wiegandt, R.; Fust, A.; Preussner, J.; Kuenne, C.; Braun, T. et al.; Kim, J.; Looso, M.: ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation. NATURE COMMUNICATIONS 11 (1), 4267 (2020)

Pflueger-Mueller, B.; Oo, J. A.; Heering, J.; Warwick, T.; Proschak, E.; Guenther, S.; Looso, M.; Rezende, F.; Fork, C.; Geisslinger, G. et al.; Thomas, D.; Gurke, R.; Steinhilber, D.; Schulz, M.; Leisegang, M. S.; Brandes, R. P.: The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells. BASIC RESEARCH IN CARDIOLOGY 115 (3), 34 (2020)