Publications of Stefan Gunther

Wittig, J.; Xu, R.; Lagos, F. D.; Drekolia, M.-K.; Zhang, B.; Theodorou, I.; Chen, Y.; Du, Y.; Gupta, L.; Hanyu, C. et al.; Yuanyuan, L.; Bo, C.; Gunther, S.; Wittig, I.; Ola, R.; Hu, J.; Bibli, S.-I.: Persulfidation alters gene regulatory programs and promotes endothelial specification. REDOX BIOLOGY 89, 103926 (2026)

Siragusa, M.; Graumann, J.; Kuenne, C.; Gunther, S.; Jeratsch, S.; Guven, B.; Susser, S.; Talyan, S.; Bezuneh, B.; Matthess, Y. et al.; Cartura, M.; Zhou, X.; Cho, H.; Sachs, N.; Maegdefessel, L.; Muller, O. J.; Troidl, C.; Nef, H. M.; Looso, M.; Kaulich, M.; Offermanns, S.; Fleming, I.: Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease. CARDIOVASCULAR RESEARCH (2026)

Kawase, H.; Liu, S.; Kurz, S.; Bengelsdorff, V.; Bonnavion, R.; Jin, Y.-J.; Roquid, K. A.; Cho, H.; Liang, G.; Banicevic, M. et al.; Shiva, N.; Yunes-Leites, P. S.; Gunther, S.; Tombor, L.; Dimmeler, S.; Looso, M.; Mattonet, K.; Wettschureck, N.; Muller, U. C.; Offermanns, S.: Endothelial soluble APP/APLP2 promote heart repair through KIT-mediated angiogenesis. SCIENCE ADVANCES 12 (21), eaeh0301 (2026)

Tarasco, M.; Juan, T.; Alayoubi, Y.; Kulkarni, R.; Schumann, A.; da Silva, A. R.; Albu, M.; Dwari, M.; Dlnija, M.; Gunther, S. et al.; Looso, M.; Stainier, D. Y. R.: Time-resolved single-cell transcriptomics maps zebrafish heart development. CELL REPORTS 45 (4), 117249 (2026)

Malainou, C.; Peteranderl, C.; Ferrero, M. R.; Vazquez-Armendariz, A. I.; Alexopoulos, I.; Franz, K.; Knippenberg, K.; Better, J.; Estiri, M.; Wu, C.-Y. et al.; Schultheis, H.; Bushe, J.; del Rio, M.-L.; Rodriguez-Barbosa, J. I.; Pfeffer, K.; Gunther, S.; Looso, M.; Gruber, A. D.; Vadasz, I.; Matt, U.; Herold, S.: TNF superfamily member 14 drives post-influenza depletion of alveolar macrophages, enabling secondary pneumococcal pneumonia. JOURNAL OF CLINICAL INVESTIGATION 136 (2), e185390 (2026)

Martinez-Mayer, J.; Balakrishnan, M.; Cheung, L. Y.; Gunther, S.; Medan, V.; Stainier, D. Y. R.; Perez-Millan, M. I.: Generation of a prop1 knock-in zebrafish enables single-cell transcriptomics of early pituitary development. ENDOCRINOLOGY 167 (5), bqag043 (2026)

Carpenter, B. J.; Lecacheur, M.; Mangold, Y. N.; Cui, K.; Gunther, S.; Vermunt, M. W.; Dierickx, P.: NAD+ controls circadian rhythmicity during cardiac aging. COMMUNICATIONS BIOLOGY 9 (1), 476 (2026)

Herrle, N.; Malacarne, P. F.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; Leisegang, M. S.; Sarakpi, T.; Wionski, S. et al.; Lopez, M.; Kader, C.; Teichmann, T.; Drekolia, M.-K.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Gunther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Bibli, S.-I.; Segarra, M.; Acker-Palmer, A.; Wagner, J. U. G.; Wittig, I.; Dimmeler, S.; Schulz, M. H.; Richards, J. B.; Gilsbach, R.; Denton, T. T.; Fleming, I.; Hannibal, L.; Brandes, R. P.; Rezende, F.: The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO JOURNAL (2025)

Heck, C.; Zimmermann-Geller, B.; Haun, S.; Lotfering, F.; Welbrink, P.; Kursammer, D.; Frommer, K. W.; Arnold-Graf, M.; Korb-Pap, A.; Knothe, A. et al.; Schulz, N.; Simianer, S.; Tarner, I.; Hermann, W.; Biehl, C.; Gunther, S.; Steinmeyer, J.; Lips, K. S.; Rickert, M.; Rehart, S.; Muller-Ladner, U.; Neumann, E.: Influence of canstatin on fibroblast-driven hypervascularisation in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES 84 (12), pp. 1968 - 1982 (2025)

Mukherjee, D.; Larcher, V.; Winter, H.; Sachs, N.; Andriani, F.; Chiesa, M.; Perrucci, G. L.; Rega, S.; Gunther, S.; Kuenne, C. et al.; Martin, J. C.; Gu, Y.; Pelisek, J.; Fischer, A.; Peruzzo, S.; Pizzo, E.; Peterson, K. L.; Dimmeler, S.; Maegdefessel, L.; Cattaneo, P.; Evans, S. M.; Guimaraes-Camboa, N.: Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis. CARDIOVASCULAR RESEARCH (2025)

Huber, L. S.; Merline, R.; Zeng-Brouwers, J.; Vutukuri, R.; Kraus, N.; Ortiz, C.; Guenther, S.; Buhl, E. M.; Hahnefeld, L.; Gurke, R. et al.; Bein, J.; Karimova, M.; Wurzel, P.; Boor, P.; Welsch, C.; Wild, P.; Pfeilschifter, J.; Kogel, D.; Wygrecka, M.; Trebicka, J.; Bartoszewski, R.; Dikic, I.; Schaefer, L.: Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 329 (5), pp. C1360 - C1379 (2025)

Georgieva, A. M.; Sreenivasan, K.; Ding, D.; Villeneuve, C.; Wickstrom, S. A.; Gunther, S.; Kuenne, C.; Gartner, U.; Guo, X.; Zhou, Y. et al.; Yuan, X.; Braun, T.: Regulation of NSL by TAF4A is critical for genome stability and quiescence of muscle stem cells. NATURE COMMUNICATIONS 16 (1), 8726 (2025)

Wang, T.; Bonnavion, R.; Piesker, J.; Guenther, S.; Wettschureck, N.: GPRC5B preserves a mature j3 cell state in obesity by controlling MafA expression. JCI INSIGHT 10 (20), e194115 (2025)

Langschied, F.; Leisegang, M. S.; Guenther, S.; Hahner, F.; Brandes, R. P.; Ebersberger, I.: Loss of multiple micro-RNAs uncovers multi-level restructuring of gene regulation in rodents. BMC GENOMICS 26 (1), 800 (2025)

Shao, J.; Kwon, J.; Wang, T.; Guenther, S.; Tombor, L. S.; Warwick, T.; Shaheryar, Z.; Brandes, R. P.; Dimmeler, S.; Wenzel, J. et al.; Offermanns, S.; Schwaninger, M.; Wettschureck, N.: Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. NATURE COMMUNICATIONS 16 (1), 6232 (2025)

Jafari, L.; Wiedenroth, C. B.; Kriechbaum, S. D.; Gruen, D.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Spaeth, A. M.; Cherian, A. V.; Troidl, C. et al.; Wilhelm, J.; Keranov, S.; Keller, T.; Kojonazarov, B.; Schermuly, R. T.; Guth, S.; Doerr, O.; Nef, H.; Boehm, M.; Spiekerkoetter, E.; Leszek, P.; Varga, Z. V.; Ferdinandy, P.; Ghofrani, H. A.; Dorfmueller, P.; Weissmann, N.; Hamm, C. W.; Mayer, E.; Seeger, W.; Liebetrau, C.; Pullamsetti, S. S.: Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery. NATURE CARDIOVASCULAR RESEARCH 4 (7) (2025)

Gajawada, P.; Guenther, S.; Rolf, A.; Nabhanizadeh, J.; Savai, R.; Choi, Y.-H.; Richter, M.: Transcriptomic profiling of granuloma in patients with cardiac sarcoidosis. THERANOSTICS 15 (13), pp. 6044 - 6057 (2025)

Constanty, F.; Wu, B.; Wei, K.-H.; Lin, I.-T.; Dallmann, J.; Guenther, S.; Lautenschlaeger, T.; Priya, R.; Lai, S.-L.; Stainier, D. Y. R. et al.; Beisaw, A.: Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration. NATURE COMMUNICATIONS 16 (1), 3823 (2025)

Panza, P.; Kim, H.-T.; Lautenschlaeger, T.; Piesker, J.; Guenther, S.; Alayoubi, Y.; Cleaver, O.; Looso, M.; Stainier, D. Y. R.: The lung microvasculature promotes alveolar type 2 cell differentiation via secreted SPARCL1. STEM CELL REPORTS 20 (4), 102451 (2025)

Gupta, S.; Bajwa, G. K.; El-Sammak, H.; Mattonet, K.; Guenther, S.; Looso, M.; Stainier, D. Y. R.; Marin-Juez, R.: The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration. DEVELOPMENTAL BIOLOGY 521, pp. 153 - 162 (2025)