Publications of Stefan Gunther

Wittig, J.; Xu, R.; Lagos, F. D.; Drekolia, M.-K.; Zhang, B.; Theodorou, I.; Chen, Y.; Du, Y.; Gupta, L.; Hanyu, C. et al.; Yuanyuan, L.; Bo, C.; Gunther, S.; Wittig, I.; Ola, R.; Hu, J.; Bibli, S.-I.: Persulfidation alters gene regulatory programs and promotes endothelial specification. REDOX BIOLOGY 89, 103926 (2026)

Malacarne, P. F.; Lopez, M.; Chatterjee, S.; Herrle, N.; Weiss, L.; Gunther, S.; Osborne, T.; Glaubitz, C.; Schmid, T.; Kurrle, N. et al.; Schnutgen, F.; Lutjohann, D.; Brandes, R. P.; Rezende, F.: Endothelial cytochrome P450-derived cholesterol limits angiogenesis. REDOX BIOLOGY 95, 104289 (2026)

Wang, L.; Staps, M.; Gunther, S.; El Agha, E.; Bellusci, S.; Kuenne, C.; Du, J.; Schneider, A.; Braun, T.: Cell Type-Specific Targeting of Different Smooth Muscle Cell Populations by Intersectional Genetics. CIRCULATION 154 (6), pp. 565 - 583 (2026)

Mansouri, S.; Hesami, G.; Ambikan, A.; Karger, A.; Klatt, S.; Neogi, U.; Kurakula, K. B.; Aliraj, B.; Miller, A.; Petrova, B. et al.; Sanda, M.; Sirait-Fischer, E.; Guenther, S.; Kuenne, C.; Ruppert, C.; Alkoudmani, I.; Gattenlohner, S.; Zukunft, S.; Fleming, I.; Haschemi, A.; Stiewe, T.; Grimminger, F.; Reck, M.; Weigert, A.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: IRG1/itaconate rewires macrophage and lung tumor metabolism through G6PD inhibition. CELL METABOLISM 38 (7), pp. 1460 - 1477 (2026)

Lam, F.; Warwick, T.; Oo, J. A.; Kruger, A. Y.; Kreis, N.-N.; Diagel, A.; Ponce, J. I.; Tirunagari, P.; Bayer, M. E.; Nonn, O. et al.; Dechend, R.; Walther, T.; Boon, R. A.; Baker, A. H.; Gunther, S.; Wittig, I.; Chen, Z.; Muller-McNicoll, M.; Louwen, F.; Brandes, R. P.; Leisegang, M. S.: LINC00607 facilitates endothelial VEGF-A receptor FLT1 splicing. MOLECULAR THERAPY 34 (7), pp. 4323 - 4338 (2026)

Shiva, N.; Kawase, H.; Einsiedel, J.; Kwon, J.; Kumar, S.; Shao, J.; Du, Z.; Kubin, N.; Shimari, M.; Gunther, S. et al.; Li, T.; Dierickx, P.; Sossalla, S.; Offermanns, S.; Gmeiner, P.; Wettschureck, N.: Neurotensin receptor 2 agonism attenuates adverse cardiac remodeling in preclinical models. SCIENCE TRANSLATIONAL MEDICINE 18 (856), eaea9877 (2026)

Raheja, M.; Guven, B.; Szymanski, W.; Gunther, S.; Kuenne, C.; Rakultsev, V.; Segarra, M.; Bozkurt, S.; Munch, C.; Kaulich, M. et al.; Graumann, J.; Fleming, I.; Siragusa, M.: A microprotein encoded by FERMT3 modulates endothelial cell protein catabolism and induces cell cycle arrest and senescence. CELL COMMUNICATION AND SIGNALING 24 (1), 372 (2026)

Candlish, M.; Hofmann, J.; Brosamle, D.; Haessler, A.; DeMeglio, M.; Skodras, A.; Tushev, G.; De Biasi, E. S.; Gunther, S.; Wiegandt, R. et al.; Theis, H.; De Domenico, E.; Hermann, N. S.; Breunig, P.; Sauerland, C.; Nilsson, K. P. R.; Beyer, M. D.; Looso, M.; Windbergs, M.; Roeber, S.; Herms, J.; Neher, J. J.; Chiocchetti, A. G.; Hefendehl, J. K.: Ischemic injury triggers a protective microglial phenotype in models of Aβ pathology. JOURNAL OF NEUROINFLAMMATION 23 (1), 213 (2026)

Yeganeh, M.; Najar-Asl, M.; Karamzadeh, R.; Nemati, S.; Yakhkeshi, S.; Akhlaghpour, A.; Guenther, S.; Naderi, S.; Shahbazi, E.; Mollamohammadi, S. et al.; Simorgh, S.; Hassani, S.-N.; Shojaei, A.; Mirnajafizadeh, J.; Abolghasemi Dehaqani, M.-R.; Ahmadabadi, M. N.; Huang, R.; Shahpasand, K.; Hisanaga, S.-I.; Braun, T.; Baharvand, H.: Human pluripotent stem cell-derived neuroepithelial cells develop into an organizer for optic tectum formation in the chicken diencephalon. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY 14, 1812038 (2026)

Siragusa, M.; Graumann, J.; Kuenne, C.; Gunther, S.; Jeratsch, S.; Guven, B.; Susser, S.; Talyan, S.; Bezuneh, B.; Matthess, Y. et al.; Cartura, M.; Zhou, X.; Cho, H.; Sachs, N.; Maegdefessel, L.; Muller, O. J.; Troidl, C.; Nef, H. M.; Looso, M.; Kaulich, M.; Offermanns, S.; Fleming, I.: Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease. CARDIOVASCULAR RESEARCH (2026)

Kawase, H.; Liu, S.; Kurz, S.; Bengelsdorff, V.; Bonnavion, R.; Jin, Y.-J.; Roquid, K. A.; Cho, H.; Liang, G.; Banicevic, M. et al.; Shiva, N.; Yunes-Leites, P. S.; Gunther, S.; Tombor, L.; Dimmeler, S.; Looso, M.; Mattonet, K.; Wettschureck, N.; Muller, U. C.; Offermanns, S.: Endothelial soluble APP/APLP2 promote heart repair through KIT-mediated angiogenesis. SCIENCE ADVANCES 12 (21), eaeh0301 (2026)

Tarasco, M.; Juan, T.; Alayoubi, Y.; Kulkarni, R.; Schumann, A.; da Silva, A. R.; Albu, M.; Dwari, M.; Dlnija, M.; Gunther, S. et al.; Looso, M.; Stainier, D. Y. R.: Time-resolved single-cell transcriptomics maps zebrafish heart development. CELL REPORTS 45 (4), 117249 (2026)

Malainou, C.; Peteranderl, C.; Ferrero, M. R.; Vazquez-Armendariz, A. I.; Alexopoulos, I.; Franz, K.; Knippenberg, K.; Better, J.; Estiri, M.; Wu, C.-Y. et al.; Schultheis, H.; Bushe, J.; del Rio, M.-L.; Rodriguez-Barbosa, J. I.; Pfeffer, K.; Gunther, S.; Looso, M.; Gruber, A. D.; Vadasz, I.; Matt, U.; Herold, S.: TNF superfamily member 14 drives post-influenza depletion of alveolar macrophages, enabling secondary pneumococcal pneumonia. JOURNAL OF CLINICAL INVESTIGATION 136 (2), e185390 (2026)

Martinez-Mayer, J.; Balakrishnan, M.; Cheung, L. Y.; Gunther, S.; Medan, V.; Stainier, D. Y. R.; Perez-Millan, M. I.: Generation of a prop1 knock-in zebrafish enables single-cell transcriptomics of early pituitary development. ENDOCRINOLOGY 167 (5), bqag043 (2026)

Carpenter, B. J.; Lecacheur, M.; Mangold, Y. N.; Cui, K.; Gunther, S.; Vermunt, M. W.; Dierickx, P.: NAD+ controls circadian rhythmicity during cardiac aging. COMMUNICATIONS BIOLOGY 9 (1), 476 (2026)

Stilz, K. A.; Leonard, V. E.; Rodriguez Morales, D.; Glaser, S.-F.; Larcher, V.; Ruz Jurado, M.; Malacarne, P. F.; Manickam, N.; Tombor, L. S.; Abplanalp, W. T. et al.; Panthel, J.; Kujundzic, H.; Fischer, A.; Schmitz, K.; Muller, O. J.; Hille, S.; Kupatt, C.; Bozoglu, T.; Sami, H.; Ogris, M.; Procida-Kowalski, T.; Bartkuhn, M.; John, D.; Yekelchyk, M.; Schmachtel, T.; Rieger, M.; Pham, M.-D.; Krishnan, J.; Gunther, S.; Brandes, R. P.; Braun, T.; Zeiher, A. M.; Wagner, J. U. G.; Dimmeler, S.: Endothelial ZBTB16: a molecular shield against cardiac aging. EUROPEAN HEART JOURNAL 47 (10), pp. 1186 - 1198 (2026)

Leberzammer, J.; Abplanalp, W. T.; Grikscheit, K.; Solomonidis, E. G.; Glaser, S.-F.; Schuhmacher, B.; Merten, M.; Jeremijev, G.; Wilken-Schmitz, A.; Korth, L. et al.; John, D.; Gunther, S.; Kuenne, C.; Looso, M.; Valasarajan, C.; Benes, V.; Jung, F.; Niehaus, V.; Anton, G.; Stellbrink, C.; Rommele, C.; Gopel, S.; Pullamsetti, S. S.; Vehreschild, J.; Vehreschild, M.; Ciesek, S.; Leistner, D. M.; Zeiher, A. M.; Dimmeler, S.; Cremer, S.: Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by interferon priming in circulating myeloid cells. CARDIOVASCULAR RESEARCH (2026)

Dizdarevic, S.; Wiegandt, R.; Weigert, A.; Stiewe, T.; Eul, B.; Guenther, S.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Looso, M. et al.; Turkowski, K.; Savai, R.: Divergent CD45+ immune landscapes shape the lung tumor microenvironment. FRONTIERS IN IMMUNOLOGY 17, 1765833 (2026)

Srivastava, S.; Gunawan, F.; Vergarajauregui, S.; Gentile, A.; Angeloni, M.; Petersen, S. C.; Gunther, S.; Ferrazzi, F.; Stainier, D. Y. R.; Engel, F. B.: Adgrg6/Gpr126 is required for compact wall integrity and establishing trabecular identity during cardiac trabeculation. NATURE COMMUNICATIONS 17 (1), 1484 (2026)

Herrle, N.; Malacarne, P. F.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; Leisegang, M. S.; Sarakpi, T.; Wionski, S. et al.; Lopez, M.; Kader, C.; Teichmann, T.; Drekolia, M.-K.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Gunther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Bibli, S.-I.; Segarra, M.; Acker-Palmer, A.; Wagner, J. U. G.; Wittig, I.; Dimmeler, S.; Schulz, M. H.; Richards, J. B.; Gilsbach, R.; Denton, T. T.; Fleming, I.; Hannibal, L.; Brandes, R. P.; Rezende, F.: The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO JOURNAL 45 (3), pp. 820 - 855 (2026)