Publications

Uszczynska-Ratajczak, B.; Sugunan, S.; Kwiatkowska, M.; Migdal, M.; Carbonell-Sala, S.; Sokol, A.; Winata, C. L.; Chacinska, A.: Profiling subcellular localization of nuclear-encoded mitochondrial gene products in zebrafish. LIFE SCIENCE ALLIANCE 6 (1), e202201514 (2023)

Oo, J. A.; Palfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomaskovic, I.; Boos, F.; Izquierdo Ponce, J.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Pham, M. D.; Krishnan, J.; Baker, A. H.; Gunther, S.; Ulrich, H. D.; Dikic, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. Cell reports 41 (7) (2022)

Chu, X.; Lingampally, A.; Moiseenko, A.; Kheirollahi, V.; Vazquez-Armendariz, A. I.; Koepke, J.; Khadim, A.; Kiliaris, G.; Felordi, M. S.; Zabihi, M. et al.; Shalashova, I.; Alexopoulos, I.; Guenther, S.; Lebrigand, K.; Truchi, M.; Guenther, A.; Braun, T.; Mari, B.; Samakovlis, C.; Li, X.; Seeger, W.; Herold, S.; Zhang, J.-S.; Bellusci, S.; El Agha, E.: GLI1+cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration. CELLULAR AND MOLECULAR LIFE SCIENCES 79 (11), 581 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Gunther, S.; Senturk Cetin, N.; Warwick, T.; Cao, C. et al.; Boos, F.; Izquierdo Ponce, J.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pfluger-Muller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. Nature communications 13 (1), 6563 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Merle, N.; Elmshaeuser, S.; Strassheimer, F.; Wanzel, M.; Koenig, A. M.; Funk, J.; Neumann, M.; Kochhan, K.; Helmprobst, F.; Pagenstecher, A. et al.; Nist, A.; Mernberger, M.; Schneider, A.; Braun, T.; Borggrefe, T.; Savai, R.; Timofeev, O.; Stiewe, T.: Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase. MOLECULAR CANCER 21 (1), 191 (2022)

Magadum, A.; Renikunta, H. V.; Singh, N.; Estaras, C.; Kishore, R.; Engel, F. B.: Live cell screening identifies glycosides as enhancers of cardiomyocyte cell cycle activity. FRONTIERS IN CARDIOVASCULAR MEDICINE 9, 901396 (2022)

Garcia-Gonzalez, C.; Dieterich, C.; Maroli, G.; Wiesnet, M.; Wietelmann, A.; Li, X.; Yuan, X.; Graumann, J.; Stellos, K.; Kubin, T. et al.; Schneider, A.; Braun, T.: ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. CIRCULATION RESEARCH 131 (7), pp. 580 - 597 (2022)

Mattonet, K.; Riemslagh, F. W.; Guenther, S.; Prummel, K. D.; Kesavan, G.; Hans, S.; Ebersberger, I.; Brand, M.; Burger, A.; Reischauer, S. et al.; Mosimann, C.; Stainier, D. Y. R.: Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. SCIENCE ADVANCES 8 (35), eabn2082 (2022)

Woods, M. L.; Weiss, A.; Sokol, A. M.; Graumann, J.; Boettger, T.; Richter, A. M.; Schermuly, R. T.; Dammann, R. H.: Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. CANCER GENE THERAPY (2022)

Georgieva, A. M.; Guo, X.; Bartkuhn, M.; Guenther, S.; Kuenne, C.; Smolka, C.; Atzberger, A.; Gaertner, U.; Mamchaoui, K.; Bober, E. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression. NATURE COMMUNICATIONS 13 (1), 4184 (2022)

Kimoloi, S.; Sen, A.; Guenther, S.; Braun, T.; Brugmann, T.; Sasse, P.; Wiesner, R. J.; Pla-Martin, D.; Baris, O. R.: Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2022)

Kim, H.-T.; Panza, P.; Kikhi, K.; Nakamichi, Y.; Atzberger, A.; Guenther, S.; Ruppert, C.; Guenther, A.; Stainier, D. Y. R.: WNT/RYK signaling functions as an antiinflammatory modulator in the lung mesenchyme. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119 (24), e2201707119 (2022)

Chelladurai, P.; Kuenne, C.; Bourgeois, A.; Guenther, S.; Valasarajan, C.; Cherian V, A.; Rottier, R. J.; Romanet, C.; Weigert, A.; Boucherat, O. et al.; Eichstaedt, C. A.; Ruppert, C.; Guenther, A.; Braun, T.; Looso, M.; Savai, R.; Seeger, W.; Bauer, U.-M.; Bonnet, S.; Pullamsetti, S. S.: Epigenetic reactivation of transcriptional programs orchestrating fetal lung development in human pulmonary hypertension. SCIENCE TRANSLATIONAL MEDICINE 14 (648), eabe5407 (2022)

Klockner, I.; Schutt, C.; Gerhardt, T.; Boettger, T.; Braun, T.: Control of CRK-RAC1 activity by the miR-1/206/133 miRNA family is essential for neuromuscular junction function. NATURE COMMUNICATIONS 13 (1), 3180 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Mueller, N.; Lopez, M.; Pflueger-Mueller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Guenther, S.; Weigert, A.; Geisslinger, G.; Luetjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. HYPERTENSION 79 (6), pp. 1216 - 1226 (2022)

Naeem, Z.; Zukunft, S.; Guenther, S.; Liebner, S.; Weigert, A.; Hammock, B. D.; Froemel, T.; Fleming, I.: Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2022)

Liang, G.; Wang, S.; Shao, J.; Jin, Y.-J.; Xu, L.; Yan, Y.; Guenther, S.; Wang, L.; Offermanns, S.: Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis. CIRCULATION RESEARCH 130 (11), pp. 1647 - 1659 (2022)

Ukan, U.; Lagos, F. D.; Kempf, S.; Gunther, S.; Siragusa, M.; Fisslthaler, B.; Fleming, I.: Effect of Thrombin on the Metabolism and Function of Murine Macrophages. CELLS 11 (10), 1718 (2022)