Publications of Nina Wettschureck

Wang, S.; Wang, B.; Shi, Y.; Moeller, T.; Stegmeyer I, R.; Strilic, B.; Li, T.; Yuan, Z.; Wang, C.; Wettschureck, N. et al.; Vestweber, D.; Offermanns, S.: Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis. BLOOD 140 (3), pp. 171 - 183 (2022)

Wang, S.; Wang, B.; Shi, Y.; Moller, T.; Stegmeyer, R. I.; Strilic, B.; Li, T.; Yuan, Z.; Wang, C.; Wettschureck, N. et al.; Vestweber, D.; Offermanns, S.: Mechanosensation by endothelial PIEZO1 is required for leukocyte diapedesis. Blood (2022)

Gurusamy, M.; Tischner, D.; Shao, J.; Klatt, S.; Zukunft, S.; Bonnavion, R.; Guenther, S.; Siebenbrodt, K.; Kestner, R.-I.; Kuhlmann, T. et al.; Fleming, I.; Offermanns, S.; Wettschureck, N.: G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. NATURE COMMUNICATIONS 12 (1), 6798 (2021)

Ishihama, S.; Yoshida, S.; Yoshida, T.; Mori, Y.; Ouchi, N.; Eguchi, S.; Sakaguchi, T.; Tsuda, T.; Kato, K.; Shimizu, Y. et al.; Ohashi, K.; Okumura, T.; Bando, Y. K.; Yagyu, H.; Wettschureck, N.; Kubota, N.; Offermanns, S.; Kadowaki, T.; Murohara, T.; Takefuji, M.: LPL/AQP7/GPD2 promotes glycerol metabolism under hypoxia and prevents cardiac dysfunction during ischemia. FASEB JOURNAL 35 (12), e22048 (2021)

Jin, Y.-J.; Chennupati, R.; Li, R.; Liang, G.; Wang, S.; Iring, A.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. JOURNAL OF CLINICAL INVESTIGATION 131 (21), e145734 (2021)

Demirel, E.; Arnold, C.; Garg, J.; Jaeger, M. A.; Sticht, C.; Li, R.; Kuk, H.; Wettschureck, N.; Hecker, M.; Korff, T.: RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells. CELLS 10 (7), 1748 (2021)

Xu, L.; Wettschureck, N.; Bai, Y.; Yuan, Z.; Wang, S.: Myofibroblast YAP/TAZ is dispensable for liver fibrosis in mice. JOURNAL OF HEPATOLOGY 75 (1), pp. 238 - 241 (2021)

Carvalho, J.; Chennupati, R.; Li, R.; Guenther, S.; Kaur, H.; Zhao, W.; Tonack, S.; Kurz, M.; Moesslein, N.; Buenemann, M. et al.; Offermanns, S.; Wettschureck, N.: Orphan G Protein-Coupled Receptor GPRC5B Controls Smooth Muscle Contractility and Differentiation by Inhibiting Prostacyclin Receptor Signaling. CIRCULATION 141 (14), pp. 1168 - 1183 (2020)

van den Bos, E.; Ambrosy, B.; Horsthemke, M.; Walbaum, S.; Bachg, A. C.; Wettschureck, N.; Innamorati, G.; Wilkie, T. M.; Hanley, P. J.: Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor?mediated chemotaxis. JOURNAL OF BIOLOGICAL CHEMISTRY 295 (22), pp. 7726 - 7742 (2020)

Wang, S.; Cao, S.; Arhatte, M.; Li, D.; Shi, Y.; Kurz, S.; Hu, J.; Wang, L.; Shao, J.; Atzberger, A. et al.; Wang, Z.; Wang, C.; Zang, W.; Fleming, I.; Wettschureck, N.; Honore, E.; Offermanns, S.: Adipocyte Piezo1 mediates obesogenic adipogenesis through the FGF1/FGFR1 signaling pathway in mice. NATURE COMMUNICATIONS 11 (1) (2020)

Chennupati, R.; Wirth, A.; Favre, J.; Li, R.; Bonnavion, R.; Jin, Y.-J.; Wietelmann, A.; Schweda, F.; Wettschureck, N.; Henrion, D. et al.; Offermanns, S.: Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance. ELIFE 8, e49374 (2019)

Iring, A.; Jin, Y.-J.; Albarran-Juarez, J.; Siragusa, M.; Wang, S.; Dancs, P. T.; Nakayama, A.; Tonack, S.; Chen, M.; Kuenne, C. et al.; Sokol, A. M.; Guenther, S.; Martinez, A.; Fleming, I.; Wettschureck, N.; Graumann, J.; Weinstein, L. S.; Offermanns, S.: Shear stress-induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure. JOURNAL OF CLINICAL INVESTIGATION 129 (7), pp. 2775 - 2791 (2019)

Sakaguchi, T.; Takefuji, M.; Wettschureck, N.; Hamaguchi, T.; Amano, M.; Kato, K.; Tsuda, T.; Eguchi, S.; Ishihama, S.; Mori, Y. et al.; Yura, Y.; Yoshida, T.; Unno, K.; Okumura, T.; Ishii, H.; Shimizu, Y.; Bando, Y. K.; Ohashi, K.; Ouchi, N.; Enomoto, A.; Offermanns, S.; Kaibuchi, K.; Murohara, T.: Protein Kinase N Promotes Stress-Induced Cardiac Dysfunction Through Phosphorylation of Myocardin-Related Transcription Factor A and Disruption of Its Interaction With Actin. CIRCULATION 140 (21), pp. 1737 - 1752 (2019)

Wettschureck, N.; Strilic, B.; Offermanns, S.: PASSING THE VASCULAR BARRIER: ENDOTHELIAL SIGNALING PROCESSES CONTROLLING EXTRAVASATION. PHYSIOLOGICAL REVIEWS 99 (3), pp. 1467 - 1525 (2019)

Albarran-Juarez, J.; Iring, A.; Wang, S.; Joseph, S.; Grimm, M.; Strilic, B.; Wettschureck, N.; Althoff, T. F.; Offermanns, S.: Piezo1 and G(q)/G(11) promote endothelial inflammation depending on flow pattern and integrin activation. JOURNAL OF EXPERIMENTAL MEDICINE 215 (10), pp. 2655 - 2672 (2018)

Breuer, J.; Herich, S.; Schneider-Hohendorf, T.; Chasan I, A.; Wettschureck, N.; Gross, C. C.; Loser, K.; Zarbock, A.; Roth, J.; Klotz, L. et al.; Wiendl, H.; Schwab, N.: Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium. MULTIPLE SCLEROSIS JOURNAL 24 (14), pp. 1871 - 1882 (2018)

Rodiger, M.; Werno, M. W.; Wilhelmi, I.; Baumeier, C.; Hesse, D.; Wettschureck, N.; Offermanns, S.; Song, K.; Krauss, M.; Schuermann, A.: Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes. MOLECULAR METABOLISM 8, pp. 167 - 179 (2018)

de Azua, I. R.; Mancini, G.; Srivastava, R. K.; Rey, A. A.; Cardinal, P.; Tedesco, L.; Zingaretti, C. M.; Sassmann, A.; Quarta, C.; Schwitter, C. et al.; Conrad, A.; Wettschureck, N.; Vemuri, V. K.; Makriyannis, A.; Hartwig, J.; Mendez-Lago, M.; Bindila, L.; Monory, K.; Giordano, A.; Cinti, S.; Marsicano, G.; Offermanns, S.; Nisoli, E.; Pagotto, U.; Cota, D.; Lutz, B.: Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages. JOURNAL OF CLINICAL INVESTIGATION 127 (11), pp. 4148 - 4162 (2017)

Kaur, H.; Carvalho, J.; Looso, M.; Singh, P.; Chennupati, R.; Preussner, J.; Guenther, S.; Albarran-Juarez, J.; Tischner, D.; Classen, S. et al.; Offermanns, S.; Wettschureck, N.: Single-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system. NATURE COMMUNICATIONS 8, 15700 (2017)

Liu, S.; Lu, S.; Xu, R.; Atzberger, A.; Guenther, S.; Wettschureck, N.; Offermanns, S.: Members of Bitter Taste Receptor Cluster Tas2r143/Tas2r135/Tas2r126 Are Expressed in the Epithelium of Murine Airways and Other Non-gustatory Tissues. FRONTIERS IN PHYSIOLOGY 8, 849 (2017)