Publications

Kim, M.; Park, J.; Kim, S.; Han, D. W.; Shin, B.; Scholer, H.; Kim, J.; Kim, K.-P.: Generation of Induced Pluripotent Stem Cells from Lymphoblastoid Cell Lines by Electroporation of Episomal Vectors. INTERNATIONAL JOURNAL OF STEM CELLS (2022)

Pleuger, C.; Ai, D.; Hoppe, M. L.; Winter, L. T.; Bohnert, D.; Karl, D.; Guenther, S.; Epelman, S.; Kantores, C.; Fijak, M. et al.; Ravens, S.; Middendorff, R.; Mayer, J. U.; Loveland, K. L.; Hedger, M.; Bhushan, S.; Meinhardt, A.; Yan, W.: The regional distribution of resident immune cells shapes distinct immunological environments along the murine epididymis. ELIFE 11, e82193 (2022)

Yoshizawa, T.; Sato, Y.; Sobuz, S. U.; Mizumoto, T.; Tsuyama, T.; Karim, M. F.; Miyata, K.; Tasaki, M.; Yamazaki, M.; Kariba, Y. et al.; Araki, N.; Araki, E.; Kajimura, S.; Oike, Y.; Braun, T.; Bober, E.; Auwerx, J.; Yamagata, K.: SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice. NATURE COMMUNICATIONS 13 (1), 7439 (2022)

Manta, C.-P.; Leibing, T.; Friedrich, M.; Nolte, H.; Adrian, M.; Schledzewski, K.; Krzistetzko, J.; Kirkamm, C.; David Schmid, C.; Xi, Y. et al.; Stojanovic, A.; Tonack, S.; de la Torre, C.; Hammad, S.; Offermanns, S.; Krueger, M.; Cerwenka, A.; Platten, M.; Goerdt, S.; Geraud, C.: Targeting of Scavenger Receptors Stabilin-1 and Stabilin-2 Ameliorates Atherosclerosis by a Plasma Proteome Switch Mediating Monocyte/Macrophage Suppression. CIRCULATION 146 (23), pp. 1783 - 1799 (2022)

Lopez, M.; Malacarne, P. F.; Ramanujam, D. P.; Warwick, T.; Mueller, N.; Hu, J.; Dewenter, M.; Weigert, A.; Guenther, S.; Gilsbach, R. et al.; Engelhardt, S.; Brandes, R. P.; Rezende, F.: Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling. FRONTIERS IN PHYSIOLOGY 13, 1056369 (2022)

Peng, W.; Kepsch, A.; Kracht, T. O.; Hasan, H.; Wijayarathna, R.; Wahle, E.; Pleuger, C.; Bhushan, S.; Guenther, S.; Kauerhof, A. C. et al.; Planinic, A.; Fietz, D.; Schuppe, H.-C.; Wygrecka, M.; Loveland, K. L.; Jezek, D.; Meinhardt, A.; Hedger, M. P.; Fijak, M.: Activin A and CCR2 regulate macrophage function in testicular fibrosis caused by experimental autoimmune orchitis. CELLULAR AND MOLECULAR LIFE SCIENCES 79 (12), 602 (2022)

Oo, J. A.; Palfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomaskovic, I.; Boos, F.; Ponce, J. I.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Minh Pham, D.; Krishnan, J.; Baker, A. H.; Guenther, S.; Ulrich, H. D.; Dikic, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. CELL REPORTS 41 (7), e111670 (2022)

Zhang, T.; Kuenne, C.; Ding, D.; Guenther, S.; Guo, X.; Zhou, Y.; Yuan, X.; Braun, T.: Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells. NATURE COMMUNICATIONS 13 (1), 6907 (2022)

Chu, X.; Lingampally, A.; Moiseenko, A.; Kheirollahi, V.; Vazquez-Armendariz, A. I.; Koepke, J.; Khadim, A.; Kiliaris, G.; Felordi, M. S.; Zabihi, M. et al.; Shalashova, I.; Alexopoulos, I.; Guenther, S.; Lebrigand, K.; Truchi, M.; Guenther, A.; Braun, T.; Mari, B.; Samakovlis, C.; Li, X.; Seeger, W.; Herold, S.; Zhang, J.-S.; Bellusci, S.; El Agha, E.: GLI1+cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration. CELLULAR AND MOLECULAR LIFE SCIENCES 79 (11), 581 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Drekolia, M.-K.; Talyan, S.; Emidio, R. C.; Boon, R. A.; Guenther, S.; Looso, M.; Dumbovic, G.; Bibli, S.-I.: Unravelling the impact of aging on the human endothelial lncRNA transcriptome. FRONTIERS IN GENETICS 13, 1035380 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)

Merle, N.; Elmshaeuser, S.; Strassheimer, F.; Wanzel, M.; Koenig, A. M.; Funk, J.; Neumann, M.; Kochhan, K.; Helmprobst, F.; Pagenstecher, A. et al.; Nist, A.; Mernberger, M.; Schneider, A.; Braun, T.; Borggrefe, T.; Savai, R.; Timofeev, O.; Stiewe, T.: Monitoring autochthonous lung tumors induced by somatic CRISPR gene editing in mice using a secreted luciferase. MOLECULAR CANCER 21 (1), 191 (2022)

Gimbel, A. T.; Koziarek, S.; Theodorou, K.; Schulz, J. F.; Stanicek, L.; Kremer, V.; Ali, T.; Guenther, S.; Kumar, S.; Jo, H. et al.; Huebner, N.; Maegdefessel, L.; Dimmeler, S.; van Heesch, S.; Boon, R. A.: Aging-regulated TUG1 is dispensable for endothelial cell function. PLOS ONE 17 (9), e0265160 (2022)

Magadum, A.; Renikunta, H. V.; Singh, N.; Estaras, C.; Kishore, R.; Engel, F. B.: Live cell screening identifies glycosides as enhancers of cardiomyocyte cell cycle activity. FRONTIERS IN CARDIOVASCULAR MEDICINE 9, 901396 (2022)

Garcia-Gonzalez, C.; Dieterich, C.; Maroli, G.; Wiesnet, M.; Wietelmann, A.; Li, X.; Yuan, X.; Graumann, J.; Stellos, K.; Kubin, T. et al.; Schneider, A.; Braun, T.: ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7. CIRCULATION RESEARCH 131 (7), pp. 580 - 597 (2022)

Mattonet, K.; Riemslagh, F. W.; Guenther, S.; Prummel, K. D.; Kesavan, G.; Hans, S.; Ebersberger, I.; Brand, M.; Burger, A.; Reischauer, S. et al.; Mosimann, C.; Stainier, D. Y. R.: Endothelial versus pronephron fate decision is modulated by the transcription factors Cloche/Npas4l, Tal1, and Lmo2. SCIENCE ADVANCES 8 (35), eabn2082 (2022)

Woods, M. L.; Weiss, A.; Sokol, A. M.; Graumann, J.; Boettger, T.; Richter, A. M.; Schermuly, R. T.; Dammann, R. H.: Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner. CANCER GENE THERAPY (2022)

Georgieva, A. M.; Guo, X.; Bartkuhn, M.; Guenther, S.; Kuenne, C.; Smolka, C.; Atzberger, A.; Gaertner, U.; Mamchaoui, K.; Bober, E. et al.; Zhou, Y.; Yuan, X.; Braun, T.: Inactivation of Sirt6 ameliorates muscular dystrophy in mdx mice by releasing suppression of utrophin expression. NATURE COMMUNICATIONS 13 (1), 4184 (2022)

Kimoloi, S.; Sen, A.; Guenther, S.; Braun, T.; Brugmann, T.; Sasse, P.; Wiesner, R. J.; Pla-Martin, D.; Baris, O. R.: Combined fibre atrophy and decreased muscle regeneration capacity driven by mitochondrial DNA alterations underlie the development of sarcopenia. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE (2022)