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Journal Article (55)

2021
Journal Article
Brunn, D.; Turkowski, K.; Gunther, S.; Weigert, A.; Muley, T.; Kriegsmann, M.; Winter, H.; Dammann, R. H.; Stathopoulos, G. T.; Thomas, M. et al.; Guenther, A.; Grimminger, F.; Pullamsetti, S. S.; Seeger, W.; Savai, R.: Interferon Regulatory Factor 9 Promotes Lung Cancer Progression via Regulation of Versican. CANCERS 13 (2), 208 (2021)
Journal Article
Chelladurai, P.; Boucherat, O.; Stenmark, K.; Kracht, M.; Seeger, W.; Bauer, U.-M.; Bonnet, S.; Pullamsetti, S. S.: Targeting histone acetylation in pulmonary hypertension and right ventricular hypertrophy. BRITISH JOURNAL OF PHARMACOLOGY 178 (1), pp. 54 - 71 (2021)
2020
Journal Article
Kuester, M. M.; Schneider, M. A.; Richter, A. M.; Richtmann, S.; Winter, H.; Kriegsmann, M.; Pullamsetti, S. S.; Stiewe, T.; Savai, R.; Muley, T. et al.; Dammann, R. H.: Epigenetic Inactivation of the Tumor Suppressor IRX1 Occurs Frequently in Lung Adenocarcinoma and Its Silencing Is Associated with Impaired Prognosis. CANCERS 12 (12), 3528 (2020)
Journal Article
Zehendner, C. M.; Valasarajan, C.; Werner, A.; Boeckel, J.-N.; Bischoff, F. C.; John, D.; Weirick, T.; Glaser, S. F.; Rossbach, O.; Jae, N. et al.; Demolli, S.; Khassafi, F.; Yuan, K.; Perez, V. A. d. J.; Michalik, K. M.; Chen, W.; Seeger, W.; Guenther, A.; Wasnick, R. M.; Uchida, S.; Zeiher, A. M.; Dimmeler, S.; Pullamsetti, S. S.: Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFR beta. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 202 (10), pp. 1445 - 1457 (2020)
Journal Article
Mamazhakypov, A.; Weiss, A.; Zukunft, S.; Sydykov, A.; Kojonazarov, B.; Wilhelm, J.; Vroom, C.; Petrovic, A.; Kosanovic, D.; Weissmann, N. et al.; Seeger, W.; Fleming, I.; Iglarz, M.; Grimminger, F.; Ghofrani, H. A.; Pullamsetti, S. S.; Schermuly, R. T.: Effects of macitentan and tadalafil monotherapy or their combination on the right ventricle and plasma metabolites in pulmonary hypertensive rats. PULMONARY CIRCULATION 10 (4), 2045894020947283 (2020)
Journal Article
Zheng, X.; Mansouri, S.; Krager, A.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Wheelock, C. E.; Savai, R.: Metabolism in tumour-associated macrophages: a quid pro quo with the tumour microenvironment. EUROPEAN RESPIRATORY REVIEW 29 (157), 200134 (2020)
Journal Article
Bensimon-Brito, A.; Ramkumar, S.; Boezio, G. L. M.; Guenther, S.; Kuenne, C.; Helker, C. S. M.; Sanchez-Iranzo, H.; Iloska, D.; Piesker, J.; Pullamsetti, S. et al.; Mercader, N.; Beis, D.; Stainier, D. Y. R.: TGF-beta Signaling Promotes Tissue Formation during Cardiac Valve Regeneration in Adult Zebrafish. DEVELOPMENTAL CELL 52 (1), pp. 9 - + (2020)
Journal Article
Chelladurai, P.; Dabral, S.; Basineni, S. R.; Chen, C.-N.; Schmoranzer, M.; Bender, N.; Feld, C.; Noetzold, R. R.; Dobreva, G.; Wilhelm, J. et al.; Jungblut, B.; Zhao, L.; Bauer, U.-M.; Seeger, W.; Pullamsetti, S. S.: Isoform-specific characterization of class I histone deacetylases and their therapeutic modulation in pulmonary hypertension. SCIENTIFIC REPORTS 10 (1), 12864 (2020)
Journal Article
El-Nikhely, N.; Karger, A.; Sarode, P.; Singh, I.; Weigert, A.; Wietelmann, A.; Stiewe, T.; Dammann, R.; Fink, L.; Grimminger, F. et al.; Barreto, G.; Seeger, W.; Pullamsetti, S. S.; Rapp, U. R.; Savai, R.: Metastasis-Associated Protein 2 Represses NF-kappa B to Reduce Lung Tumor Growth and Inflammation. CANCER RESEARCH 80 (19), pp. 4199 - 4211 (2020)
Journal Article
Pullamsetti, S. S.; Mamazhakypov, A.; Weissmann, N.; Seeger, W.; Savai, R.: Hypoxia-inducible factor signaling in pulmonary hypertension. JOURNAL OF CLINICAL INVESTIGATION 130 (11), pp. 5638 - 5651 (2020)
Journal Article
Rakow, S.; Pullamsetti, S. S.; Bauer, U.-M.; Bouchard, C.: Assaying epigenome functions of PRMTs and their substrates. METHODS 175, pp. 53 - 65 (2020)
Journal Article
Salazar, Y.; Zheng, X.; Brunn, D.; Raifer, H.; Picard, F.; Zhang, Y.; Winter, H.; Guenther, S.; Weigert, A.; Weigmann, B. et al.; Dumoutier, L.; Renauld, J.-C.; Waisman, A.; Schmall, A.; Tufman, A.; Fink, L.; Bruene, B.; Bopp, T.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Huber, M.; Savai, R.: Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer. JOURNAL OF CLINICAL INVESTIGATION 130 (7), pp. 3560 - 3575 (2020)
Journal Article
Sarode, P.; Zheng, X.; Giotopoulou, G. A.; Weigert, A.; Kuenne, C.; Guenther, S.; Friedrich, A.; Gattenloehner, S.; Stiewe, T.; Bruene, B. et al.; Grimminger, F.; Stathopoulos, G. T.; Pullamsetti, S. S.; Seeger, W.; Savai, R.: Reprogramming of tumor-associated macrophages by targeting beta-catenin/FOSL2/ARID5A signaling: A potential treatment of lung cancer. SCIENCE ADVANCES 6 (23), eaaz6105 (2020)
Journal Article
Sindi, H. A.; Russomanno, G.; Satta, S.; Abdul-Salam, V. B.; Jo, K. B.; Qazi-Chaudhry, B.; Ainscough, A. J.; Szulcek, R.; Bogaard, H. J.; Morgan, C. C. et al.; Pullamsetti, S. S.; Alzaydi, M. M.; Rhodes, C. J.; Piva, R.; Eichstaedt, C. A.; Gruenig, E.; Wilkins, M. R.; Wojciak-Stothard, B.: Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension. NATURE COMMUNICATIONS 11 (1), 1185 (2020)
Journal Article
Turkowski, K.; Herzberg, F.; Guenther, S.; Brunn, D.; Weigert, A.; Meister, M.; Muley, T.; Kriegsmann, M.; Schneider, M. A.; Winter, H. et al.; Thomas, M.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibroblast Growth Factor-14 Acts as Tumor Suppressor in Lung Adenocarcinomas. CELLS 9 (8), 1755 (2020)
Journal Article
Zheng, X.; Weigert, A.; Reu, S.; Guenther, S.; Mansouri, S.; Bassaly, B.; Gattenlohner, S.; Grimminger, F.; Pullamsetti, S. S.; Seeger, W. et al.; Winter, H.; Savai, R.: Spatial Density and Distribution of Tumor-Associated Macrophages Predict Survival in Non-Small Cell Lung Carcinoma. CANCER RESEARCH 80 (20), pp. 4414 - 4425 (2020)
2019
Journal Article
Weiss, A.; Boehm, M.; Egemnazarov, B.; Grimminger, F.; Pullamsetti, S. S.; Kwapiszewska, G.; Schermuly, R. T.: Kinases as potential targets for treatment of pulmonary hypertension and right ventricular dysfunction. BRITISH JOURNAL OF PHARMACOLOGY (2019)
Journal Article
Dabral, S.; Muecke, C.; Valasarajan, C.; Schmoranzer, M.; Wietelmann, A.; Semenza, G. L.; Meister, M.; Muley, T.; Seeger-Nukpezah, T.; Samakovlis, C. et al.; Weissmann, N.; Grimminger, F.; Seeger, W.; Savai, R.; Pullamsetti, S. S.: A RASSF1A-HIF1 alpha loop drives Warburg effect in cancer and pulmonary hypertension. NATURE COMMUNICATIONS 10, 2130 (2019)
Journal Article
Hu, C.-J.; Zhang, H.; Laux, A.; Pullamsetti, S. S.; Stenmark, K. R.: Mechanisms contributing to persistently activated cell phenotypes in pulmonary hypertension. JOURNAL OF PHYSIOLOGY-LONDON 597 (4), pp. 1103 - 1119 (2019)
Journal Article
Humbert, M.; Guignabert, C.; Bonnet, S.; Dorfmuller, P.; Klinger, J. R.; Nicolls, M. R.; Olschewski, A. J.; Pullamsetti, S. S.; Schermuly, R. T.; Stenmark, K. R. et al.; Rabinovitch, M.: Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives. EUROPEAN RESPIRATORY JOURNAL 53 (1), 1801887 (2019)
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