Publications of Soni Savai Pullamsetti

Jafari, L.; Wiedenroth, C. B.; Kriechbaum, S. D.; Gruen, D.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Spaeth, A. M.; Cherian, A. V.; Troidl, C. et al.; Wilhelm, J.; Keranov, S.; Keller, T.; Kojonazarov, B.; Schermuly, R. T.; Guth, S.; Doerr, O.; Nef, H.; Boehm, M.; Spiekerkoetter, E.; Leszek, P.; Varga, Z. V.; Ferdinandy, P.; Ghofrani, H. A.; Dorfmueller, P.; Weissmann, N.; Hamm, C. W.; Mayer, E.; Seeger, W.; Liebetrau, C.; Pullamsetti, S. S.: Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery. NATURE CARDIOVASCULAR RESEARCH 4 (7) (2025)

Schmerer, N.; Janga, H.; Aillaud, M.; Hoffmann, J.; Aznaourova, M.; Wende, S.; Steding, H.; Halder, L. D.; Uhl, M.; Boldt, F. et al.; Stiewe, T.; Nist, A.; Jerrentrup, L.; Kirschbaum, A.; Ruppert, C.; Rossbach, O.; Ntini, E.; Marsico, A.; Valasarajan, C.; Backofen, R.; Linne, U.; Pullamsetti, S. S.; Schmeck, B.; Schulte, L. N.: A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages. NATURE COMMUNICATIONS 16 (1), 4733 (2025)

Baxan, N.; Zhao, L.; Ashek, A.; Niglas, M.; Wang, D.; Khassafi, F.; Sabrin, F.; Dubois, O.; Chen, C.-N.; Pullamsetti, S. S. et al.; Wilkins, M.; Zhao, L.: Deep phenotyping the right ventricle to establish translational MRI biomarkers for characterization of adaptive and maladaptive states in pulmonary hypertension. SCIENTIFIC REPORTS 14 (1), 29774 (2024)

Baxan, N.; Zhao, L.; Ashek, A.; Niglas, M.; Wang, D.; Khassafi, F.; Sabrin, F.; Dubois, O.; Chen, C.-N.; Pullamsetti, S. S. et al.; Wilkins, M.; Zhao, L.: Deep phenotyping the right ventricle to establish translational MRI biomarkers for characterization of adaptive and maladaptive states in pulmonary hypertension. SCIENTIFIC REPORTS 14 (1), 29774 (2024)

Zierden, M.; Berghausen, E. M.; Gnatzy-Feik, L.; Millarg, C.; Picard, F. S. R.; Kiljan, M.; Geissen, S.; Polykratis, A.; Zimmermann, L.; Nies, R. J. et al.; Pasparakis, M.; Baldus, S.; Valasarajan, C.; Pullamsetti, S. S.; Winkels, H.; Vantler, M.; Rosenkranz, S.: Hematopoietic PI3KS deficiency aggravates murine atherosclerosis through impairment of Tregs. JCI INSIGHT 9 (22), e155626 (2024)

Guignabert, C.; Aman, J.; Bonnet, S.; Dorfmueller, P.; Olschewski, A. J.; Pullamsetti, S.; Rabinovitch, M.; Schermuly, R. T.; Humbert, M.; Stenmark, K. R.: Pathology and pathobiology of pulmonary hypertension: current insights and future directions. EUROPEAN RESPIRATORY JOURNAL 64 (4), 2401095 (2024)

Guignabert, C.; Aman, J.; Bonnet, S.; Dorfmueller, P.; Olschewski, A. J.; Pullamsetti, S.; Rabinovitch, M.; Schermuly, R. T.; Humbert, M.; Stenmark, K. R.: Pathology and pathobiology of pulmonary hypertension: current insights and future directions. EUROPEAN RESPIRATORY JOURNAL 64 (4), 2401095 (2024)

Cekay, M.; Arndt, P. F.; Franken, J. K.; Wilhelm, J.; Pullamsetti, S. S.; Roller, F. C.; Sommer, N.; Askevold, I.; Luedecke, G.; Langer, C. et al.; Stein, M.; Zeppernick, F.; Tello, K.; Sibelius, U.; Grimminger, F.; Seeger, W.; Savai, R.; Eul, B.: Non-invasive surrogate markers of pulmonary hypertension are associated with poor survival in patients with cancer. BMJ OPEN RESPIRATORY RESEARCH 11 (1), e001916 (2024)

Turkowski, K.; Herzberg, F.; Guenther, S.; Weigert, A.; Haselbauer, T.; Fink, L.; Brunn, D.; Grimminger, F.; Seeger, W.; Sueltmann, H. et al.; Stiewe, T.; Pullamsetti, S. S.; Savai, R.: miR-147b mediated suppression of DUSP8 promotes lung cancer progression. ONCOGENE (2024)

Eichstaedt, C. A.; Bikou, O.; Sommer, N.; Schermuly, R. T.; Pullamsetti, S. S.; Weissmann, N.; Harbaum, L.; Tabeling, C.; Wissmueller, M.; Foris, V. et al.; Kuebler, W. M.; Hinderhofer, K.; Olschewski, A.; Kwapiszewska, G.: Genetic diagnostics and molecular approaches in pulmonary arterial hypertension. PNEUMOLOGIE 77 (11), pp. 862 - 870 (2023)

Khassafi, F.; Chelladurai, P.; Valasarajan, C.; Nayakanti, S. R.; Martineau, S.; Sommer, N.; Yokokawa, T.; Boucherat, O.; Kamal, A.; Kiely, D. G. et al.; Swift, A. J.; Alabed, S.; Omura, J.; Breuils-Bonnet, S.; Kuenne, C.; Potus, F.; Guenther, S.; Savai, R.; Seeger, W.; Looso, M.; Zaugg, J. B.; Tello, K.; Provencher, S.; Bonnet, S.; Pullamsetti, S. S.: Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. NATURE CARDIOVASCULAR RESEARCH 2 (10), pp. 917 - + (2023)

Karger, A.; Mansouri, S.; Leisegang , M. S.; Weigert, A.; Guenther, S.; Kuenne, C.; Wittig , I.; Zukunft , S.; Klatt , S.; Aliraj , B. et al.; Klotz V , L.; Winter , H.; Mahavadi, P.; Fleming , I.; Ruppert , C.; Witte , B.; Alkoudmani , I.; Gattenloehner, S.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. EMBO JOURNAL (2023)

Zheng, X.; Sarode, P.; Weigert , A.; Turkowski, K.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Winter , H.; Stenzinger, A.; Reu, S. et al.; Grimminger, F.; Stiewe, T.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. CANCER RESEARCH 83 (14), pp. 2345 - 2357 (2023)

Goncharova , E. A.; V. Kudryashova , T.; Pullamsetti, S. S.: Too hot? Too cold? Wnt signalling in pulmonary arterial hypertension: can we treat it "just right"? EUROPEAN RESPIRATORY JOURNAL 61 (6), 2300504 (2023)

Goldschmid, H.; Kluck, K.; Ball, M.; Kirchner, M.; Allgaeuer, M.; Winter, H.; Herth, F.; Heussel, C.-P.; Pullamsetti, S. S.; Savai, R. et al.; Yong, T. T. K.; Schirmacher, P.; Peters, S.; Thomas, M.; Christopoulos, P.; Budczies, J.; Stenzinger, A.; Kazdal, D.: Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naive lung adenocarcinomas. LUNG CANCER 180, 107212 (2023)

Nayakanti, S. R.; Friedrich, A.; Sarode, P.; Jafari, L.; Maroli, G.; Boehm, M.; Bourgeois, A.; Grobs, Y.; Khassafi, F.; Kuenne, C. et al.; Guenther, S.; Dabral, S.; Wilhelm, J.; Weiss, A.; Wietelmann, A.; Kojonazarov, B.; Janssen, W.; Looso, M.; de Man, F.; Provencher, S.; Tello, K.; Seeger, W.; Bonnet, S.; Savai, R.; Schermuly, R.; Pullamsetti, S. S.: Targeting Wnt-ss-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling. CIRCULATION RESEARCH 132 (11), pp. 1468 - 1485 (2023)

Selle, J.; Bohl, K.; Hoepker, K.; Wilke, R.; Dinger, K.; Kasper, P.; Abend, B.; Schermer, B.; Mueller, R.-U.; Kurschat, C. et al.; Nuesken, K.-D.; Nuesken, E.; Meyer, D.; Savai Pullamsetti, S.; Schumacher, B.; Doetsch, J.; Alcazar, M. A. A.: Perinatal Obesity Sensitizes for Premature Kidney Aging Signaling. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24 (3), 2508 (2023)

Boos, F.; Oo, J. A.; Warwick, T.; Guenther, S.; Ponce, J. I.; Lopez, M.; Rafii, D.; Buchmann, G.; Pham, M. D.; Msheik, Z. S. et al.; Li, T.; Seredinski, S.; Haydar, S.; Kashefiolasl, S.; Plate, K. H.; Behr, R.; Mietsch, M.; Krishnan, J.; Pullamsetti, S. S.; Bibli, S.-I.; Hinkel, R.; Baker, A. H.; Boon, R. A.; Schulz, M. H.; Wittig, I.; Miller Jr., F. J.; Brandes, R. P.; Leisegang, M. S.: The endothelial-enriched lncRNA LINC00607 mediates angiogenic function. BASIC RESEARCH IN CARDIOLOGY 118 (1), 5 (2023)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Weigert, A.; Zheng, X.; Nenzel, A.; Turkowski, K.; Guenther, S.; Strack, E.; Sirait-Fischer, E.; Elwakeel, E.; Kur, I. M.; Nikam, V. S. et al.; Valasarajan, C.; Winter, H.; Wissgott, A.; Voswinkel, R.; Grimminger, F.; Brune, B.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. NATURE COMMUNICATIONS 13 (1), 6078 (2022)