Journal Article (1330)

2025
Journal Article
Xu, L.; Li, T.; Cao, Y.; He, Y.; Shao, Z.; Liu, S.; Wang, B.; Su, A.; Tian, H.; Li, Y. et al.; Liang, G.; Wang, C.; Shyy, J.; Xiong, Y.; Chen, F.; Yuan, J. X.J.; Liu, J.; Zhou, B.; Wettschureck, N.; Offermanns, S.; Yan, Y.; Yuan, Z.; Wang, S.: PIEZO1 mediates periostin myofibroblast activation and pulmonary fibrosis in mice. JOURNAL OF CLINICAL INVESTIGATION 135 (11), e184158 (2025)
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Leko, L.; Simic, D.; Martins, T. V.; da Silva, G. V. L.; Maillet, I.; Savigny, F.; Vuksan, L.; Rodrigues, D. d. M.; Le Bert, M.; Offermanns, S. et al.; Riteau, N.; Togbe, D.; Quesniaux, V. F.; Russo, R. C.; Alves-Filho, J. C.; Ryffel, B.: Butyrate receptor HCAR2/GPR109A controls imiquimod-induced psoriasis-like skin inflammation. JOURNAL OF IMMUNOLOGY (2025)
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Liu, H.; Tang, Y.; Singh, A.; Vong, J.; Cordero, J.; Mathes, A.; Gao, R.; Jia, Y.; Garvalov, B. K.; Acker, T. et al.; Poschet, G.; Hell, R.; Schneider, M. A.; Heineke, J.; Wieland, T.; Barreto, G.; Cerwenka, A.; Potente, M.; Bibli, S.-I.; Savai, R.; Dobreva, G.: RNF20 links the DNA damage response and metabolic rewiring in lung cancer through HIF1α. NATURE COMMUNICATIONS 16 (1), 4929 (2025)
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Dobersch, S.; Yamamoto, N.; Schutter, A.; Cavender, S. M.; Robertson, T. M.; Kartha, N.; Samraj, A. N.; Doron, B.; Poole, L. A.; Wladyka, C. L. et al.; Zhang, A.; Jang, G. H.; Mahalingam, A. H.; Barreto, G.; Raghavan, S.; Narla, G.; Notta, F.; Eisenman, R. N.; Hsieh, A. C.; Kugel, S.: HMGA2 and protein leucine methylation drive pancreatic cancer lineage plasticity. NATURE COMMUNICATIONS 16 (1), 4866 (2025)
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Schmerer, N.; Janga, H.; Aillaud, M.; Hoffmann, J.; Aznaourova, M.; Wende, S.; Steding, H.; Halder, L. D.; Uhl, M.; Boldt, F. et al.; Stiewe, T.; Nist, A.; Jerrentrup, L.; Kirschbaum, A.; Ruppert, C.; Rossbach, O.; Ntini, E.; Marsico, A.; Valasarajan, C.; Backofen, R.; Linne, U.; Pullamsetti, S. S.; Schmeck, B.; Schulte, L. N.: A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages. NATURE COMMUNICATIONS 16 (1), 4733 (2025)
Journal Article
Better, J.; Estiri, M.; Wetstein, M.; Pervizaj-Oruqaj, L.; Malainou, C.; Ogungbemi-Alt, V.; Ferrero, M. R.; Langelage, M.; Kuznetsova, I.; Vazquez-Armendariz, A. I. et al.; Kimmig, L.; Pak, O.; Mansouri, S.; Savai, R.; Wilhelm, J.; Alexopoulos, I.; Sommer, N.; Herold, S.; Matt, U.: Cell type-specific efferocytosis determines functional plasticity of alveolar macrophages. SCIENCE IMMUNOLOGY 10 (107), eadl3852 (2025)
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Gajawada, P.; Guenther, S.; Rolf, A.; Nabhanizadeh, J.; Savai, R.; Choi, Y.-H.; Richter, M.: Transcriptomic profiling of granuloma in patients with cardiac sarcoidosis. THERANOSTICS 15 (13), pp. 6044 - 6057 (2025)
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Constanty, F.; Wu, B.; Wei, K.-H.; Lin, I.-T.; Dallmann, J.; Guenther, S.; Lautenschlaeger, T.; Priya, R.; Lai, S.-L.; Stainier, D. Y. R. et al.; Beisaw, A.: Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration. NATURE COMMUNICATIONS 16 (1), 3823 (2025)
Journal Article
Kosinska, J.; Assmann, J. C.; Inderhees, J.; Mueller-Fielitz, H.; Haendler, K.; Geisler, S.; Kuenstner, A.; Busch, H.; Worthmann, A.; Heeren, J. et al.; Sadik, C. D.; Gunzer, M.; Prevot, V.; Nogueiras, R.; Hirose, M.; Spielmann, M.; Offermanns, S.; Wettschureck, N.; Schwaninger, M.: Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR2. ELIFE 14, e98970 (2025)
Journal Article
Santos, M. C.; Birkenfeld, L.; Pham, T.; Maier, S.; Paulus, K.; Ullemeyer, L.; Knauer, A.; Kabagema-Bilan, C.; Laengst, N.; Roslan, A. et al.; Wettschureck, N.; Gawaz, M.; Ichinose, F.; Lukowski, R.: Angiotensin II-induced cardiac fibrosis and dysfunction are exacerbated by deletion of cGKI in periostin plus myofibroblasts. CLINICAL SCIENCE 139 (11), pp. 507 - 526 (2025)
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Huang, X.; Gu, L.; Sun, J.; Eils, R.: Bridging the gaps: Overcoming challenges of implementing AI in healthcare. MED 6 (4), 100666 (2025)
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Chen, X.; Shao, J.; Brandenburger, I.; Qian, W.; Hahnefeld, L.; Bonnavion, R.; Cho, H.; Wang, S.; Hidalgo, J.; Wettschureck, N. et al.; Geisslinger, G.; Gurke, R.; Wang, Z.; Offermanns, S.: FFAR4-mediated IL-6 release from islet macrophages promotes insulin secretion and is compromised in type-2 diabetes. NATURE COMMUNICATIONS 16 (1), 3422 (2025)
Journal Article
Panza, P.; Kim, H.-T.; Lautenschlaeger, T.; Piesker, J.; Guenther, S.; Alayoubi, Y.; Cleaver, O.; Looso, M.; Stainier, D. Y. R.: The lung microvasculature promotes alveolar type 2 cell differentiation via secreted SPARCL1. STEM CELL REPORTS 20 (4), 102451 (2025)
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Sun, L.; Leng, R.; Liu, M.; Su, M.; He, Q.; Zhang, Z.; Liu, Z.; Wang, Z.; Jiang, H.; Wang, L. et al.; Guo, S.; Xu, Y.; Huo, Y.; Miller, C. L.; Banach, M.; Huang, Y.; Evans, P. C.; Pelisek, J.; Camici, G. G.; Berk, B. C.; Offermanns, S.; Ge, J.; Xu, S.; Weng, J.: Endothelial MICU1 protects against vascular inflammation and atherosclerosis by inhibiting mitochondrial calcium uptake. JOURNAL OF CLINICAL INVESTIGATION 135 (7), e181928 (2025)
Journal Article
Xu, S.; Liu, Z.; Tian, T.; Zhao, W.; Wang, Z.; Liu, M.; Xu, M.; Zhang, F.; Zhang, Z.; Chen, M. et al.; Yin, Y.; Su, M.; Fang, W.; Pan, W.; Liu, S.; Li, M.-d.; Little, P. J.; Kamato, D.; Zhang, S.; Wang, D.; Offermanns, S.; Speakman, J. R.; Weng, J.: The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21. SCIENCE ADVANCES 11 (13), eadt3142 (2025)
Journal Article
Ianni, A.; Vaquero, A.; Braun, T.: Fibroblastic niches in action: CCL19+ reticular cells drive anti-tumor immunity in lung cancer. SIGNAL TRANSDUCTION AND TARGETED THERAPY 10 (1), 96 (2025)
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Manickam, N.; Sultan, I.; Panthel, J.; Kujundzic, H.; Fischer, A.; Schmitz, K.; Jurado, M. R.; Morales, D. R.; John, D.; Glaser, S.-F. et al.; Stilz, K. A.; Malacarne, P. F.; Brandes, R. P.; Braun, T.; Lerchenmueller, C.; Betge, F.; Abplanalp, W. T.; Alitalo, K.; Dimmeler, S.; Wagner, J. U. G.: Beneficial effects of vascular endothelial growth factor B gene transfer in the aged heart. CARDIOVASCULAR RESEARCH (2025)
Journal Article
Bhingardeve, S.; Sagvekar, P.; Desai, S.; Mangoli, V.; Jagtap, R.; Mukherjee, S.: The regulatory interplay between miRNA and DNA methylation orchestrates vital ovarian functions and associated traits in PCOS. GENE 940, 149165 (2025)
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Falcucci, L.; Dooley, C. M.; Adamoski, D.; Juan, T.; Martinez, J.; Georgieva, A. M.; Mamchaoui, K.; Cirzi, C.; Stainier, D. Y. R.: Transcriptional adaptation upregulates utrophin in Duchenne muscular dystrophy. NATURE (639(8054)), pp. 493 - 502 (2025)
Journal Article
Nawn, D.; Hassan, S. S.; Hromic-Jahjefendic, A.; Bhattacharya, T.; Basu, P.; Redwan, E. M.; Barh, D.; Andrade, B. S.; Aljabali, A. A.; Serrano-Aroca, A. et al.; Lundstrom, K.; Tambuwala, M. M.; Uversky, V. N.: Molecular genomic insights into melanoma associated proteins PRAME and BAP1. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2025)
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