Publikationen von Timothy Warwick

Herrle, N.; Malacarne, P. F.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; Leisegang, M. S.; Sarakpi, T.; Wionski, S. et al.; Lopez, M.; Kader, C.; Teichmann, T.; Drekolia, M.-K.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Gunther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Bibli, S.-I.; Segarra, M.; Acker-Palmer, A.; Wagner, J. U. G.; Wittig, I.; Dimmeler, S.; Schulz, M. H.; Richards, J. B.; Gilsbach, R.; Denton, T. T.; Fleming, I.; Hannibal, L.; Brandes, R. P.; Rezende, F.: The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO JOURNAL (2025)

Shao, J.; Kwon, J.; Wang, T.; Guenther, S.; Tombor, L. S.; Warwick, T.; Shaheryar, Z.; Brandes, R. P.; Dimmeler, S.; Wenzel, J. et al.; Offermanns, S.; Schwaninger, M.; Wettschureck, N.: Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. NATURE COMMUNICATIONS 16 (1), 6232 (2025)

Teichmann, T.; Pflueger-Mueller, B.; Gimenez, V. M. M.; Sailer, F.; Dirks, H.; Zehr, S.; Warwick, T.; Brettner, F.; Munoz-Tello, P.; Zimmer, A. et al.; Tegeder, I.; Thomas, D.; Gurke, R.; Guenther, S.; Heering, J.; Proschak, E.; Geisslinger, G.; Bibli, I.-S.; zu Heringdorf, D. M.; Manucha, W.; Windbergs, M.; Knapp, S.; Weigert, A.; Leisegang, M. S.; Kojetin, D.; Brandes, R. P.: The endocannabinoid anandamide mediates anti-inflammatory effects through activation of NR4A nuclear receptors. BRITISH JOURNAL OF PHARMACOLOGY (2024)

Weiss, L. M.; Warwick, T.; Zehr, S.; Guenther, S.; Wolf, S.; Schmachtel, T.; Ponce, J. I.; Palfi, K.; Teichmann, T.; Schneider, A. et al.; Stoetzel, J.; Knapp, S.; Weigert, A.; Savai, R.; Rieger, M. A.; Oellerich, T.; Wittig, I.; Oo, J. A.; Brandes, R. P.; Leisegang, M. S.: RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions. COMMUNICATIONS BIOLOGY 7 (1), 1131 (2024)

Teichmann, T.; Malacarne, P.; Zehr, S.; Guenther, S.; Pflueger-Mueller, B.; Warwick, T.; Brandes, R. P.: NCoR1 limits angiogenic capacity by altering Notch signaling. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 188, S. 65 - 78 (2024)

Warwick, T.; Buchmann, G. K.; Pflueger-Mueller, B.; Spaeth, M.; Schuermann, C.; Abplanalp, W.; Tombor, L.; John, D.; Weigert, A.; Leo-Hansmann, M. et al.; Dimmeler, S.; Brandes, R. P.: Acute injury to the mouse carotid artery provokes a distinct healing response. FRONTIERS IN PHYSIOLOGY 14, 1125864 (2023)

Boos, F.; Oo, J. A.; Warwick, T.; Guenther, S.; Ponce, J. I.; Lopez, M.; Rafii, D.; Buchmann, G.; Pham, M. D.; Msheik, Z. S. et al.; Li, T.; Seredinski, S.; Haydar, S.; Kashefiolasl, S.; Plate, K. H.; Behr, R.; Mietsch, M.; Krishnan, J.; Pullamsetti, S. S.; Bibli, S.-I.; Hinkel, R.; Baker, A. H.; Boon, R. A.; Schulz, M. H.; Wittig, I.; Miller Jr., F. J.; Brandes, R. P.; Leisegang, M. S.: The endothelial-enriched lncRNA LINC00607 mediates angiogenic function. BASIC RESEARCH IN CARDIOLOGY 118 (1), 5 (2023)

Lopez, M.; Malacarne, P. F.; Ramanujam, D. P.; Warwick, T.; Mueller, N.; Hu, J.; Dewenter, M.; Weigert, A.; Guenther, S.; Gilsbach, R. et al.; Engelhardt, S.; Brandes, R. P.; Rezende, F.: Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling. FRONTIERS IN PHYSIOLOGY 13, 1056369 (2022)

Oo, J. A.; Palfi, K.; Warwick, T.; Wittig, I.; Prieto-Garcia, C.; Matkovic, V.; Tomaskovic, I.; Boos, F.; Ponce, J. I.; Teichmann, T. et al.; Petriukov, K.; Haydar, S.; Maegdefessel, L.; Wu, Z.; Minh Pham, D.; Krishnan, J.; Baker, A. H.; Guenther, S.; Ulrich, H. D.; Dikic, I.; Leisegang, M. S.; Brandes, R. P.: Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2. CELL REPORTS 41 (7), e111670 (2022)

Leisegang, M. S.; Bains, J. K.; Seredinski, S.; Oo, J. A.; Krause, N. M.; Kuo, C.-C.; Guenther, S.; Cetin, N. S.; Warwick, T.; Cao, C. et al.; Boos, F.; Ponce, J. I.; Haydar, S.; Bednarz, R.; Valasarajan, C.; Fuhrmann, D. C.; Preussner, J.; Looso, M.; Pullamsetti, S. S.; Schulz, M. H.; Jonker, H. R. A.; Richter, C.; Rezende, F.; Gilsbach, R.; Pflueger-Mueller, B.; Wittig, I.; Grummt, I.; Ribarska, T.; Costa, I. G.; Schwalbe, H.; Brandes, R. P.: HIF1 alpha-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex. NATURE COMMUNICATIONS 13 (1), 6563 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Mueller, N.; Lopez, M.; Pflueger-Mueller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Guenther, S.; Weigert, A.; Geisslinger, G.; Luetjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. HYPERTENSION 79 (6), S. 1216 - 1226 (2022)

Malacarne, P. F.; Bezzenberger, J.; Lopez, M.; Warwick, T.; Mueller, N.; Brandes, R. P.; Rezende, F.: Epoxyeicosatrienoic Acid and Prostanoid Crosstalk at the Receptor and Intracellular Signaling Levels to Maintain Vascular Tone. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 23 (11), 5939 (2022)

Seredinski, S.; Boos, F.; Guenther, S.; Oo, J. A.; Warwick, T.; Ponce, J. I.; Lillich, F. F.; Proschak, E.; Knapp, S.; Gilsbach, R. et al.; Pflueger-Mueller, B.; Brandes, R. P.; Leisegang, M. S.: DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells. MOLECULAR THERAPY-NUCLEIC ACIDS 27, S. 1023 - 1035 (2022)

Muller, N.; Warwick, T.; Noack, K.; Malacarne, P. F.; Cooper, A. J. L.; Weissmann, N.; Schroder, K.; Brandes, R. P.; Rezende, F.: Reactive Oxygen Species Differentially Modulate the Metabolic and Transcriptomic Response of Endothelial Cells. Antioxidants (Basel, Switzerland) 11 (2), S. 434 (2022)

Hahner, F.; Moll, F.; Warwick, T.; Hebchen, D. M.; Buchmann, G. K.; Epah, J.; Abplanalp, W.; Schader, T.; Gunther, S.; Gilsbach, R. et al.; Brandes, R. P.; Schroder, K.: Nox4 promotes endothelial differentiation through chromatin remodeling. Redox biology 55, 102381 (2022)

Malacarne, P. F.; Ratiu, C.; Gajos-Draus, A.; Muller, N.; Lopez, M.; Pfluger-Muller, B.; Ding, X.; Warwick, T.; Oo, J.; Siragusa, M. et al.; Angioni, C.; Gunther, S.; Weigert, A.; GeiSSlinger, G.; Lutjohann, D.; Schunck, W.-H.; Fleming, I.; Brandes, R. P.; Rezende, F.: Loss of Endothelial Cytochrome P450 Reductase Induces Vascular Dysfunction in Mice. Hypertension (Dallas, Tex.: 1979) (2022)

Warwick, T.; Schulz, M. H.; Gilsbach, R.; Brandes, R. P.; Seuter, S.: Nuclear receptor activation shapes spatial genome organization essential for gene expression control: lessons learned from the vitamin D receptor. Nucleic acids research (2022)

Warwick, T.; Seredinski, S.; Krause, N. M.; Bains, J. K.; Althaus, L.; Oo, J. A.; Bonetti, A.; Dueck, A.; Engelhardt, S.; Schwalbe, H. et al.; Leisegang, M. S.; Schulz, M. H.; Brandes, R. P.: A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA-DNA interactions. Briefings in bioinformatics (2022)

Buchmann, G. K.; Schurmann, C.; Spaeth, M.; Abplanalp, W.; Tombor, L.; John, D.; Warwick, T.; Rezende, F.; Weigert, A.; Shah, A. M. et al.; Hansmann, M.-L.; Weissmann, N.; Dimmeler, S.; Schroder, K.; Brandes, R. P.: The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice. Redox biology 45, S. 102050 - 102050 (2021)

Warwick, T.; Schulz, M. H.; Guenther, S.; Gilsbach, R.; Neme, A.; Carlberg, C.; Brandes, R. P.; Seuter, S.: A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes. SCIENTIFIC REPORTS 11 (1), 6518 (2021)