Publikationen von Stefan Gunther

Wittig, J.; Xu, R.; Lagos, F. D.; Drekolia, M.-K.; Zhang, B.; Theodorou, I.; Chen, Y.; Du, Y.; Gupta, L.; Hanyu, C. et al.; Yuanyuan, L.; Bo, C.; Gunther, S.; Wittig, I.; Ola, R.; Hu, J.; Bibli, S.-I.: Persulfidation alters gene regulatory programs and promotes endothelial specification. REDOX BIOLOGY 89, 103926 (2026)

Drekolia, M.-K.; Mettner, J.; Wang, D.; Lagos, F. D.; Koch, C.; Hecker, D.; Eresch, J.; Mao, Y.; Bahr, M.; Weichenhan, D. et al.; Cordero, J.; Wittig, J.; Zhang, B.; Cui, H.; Li, X.; Oo, J. A.; Weigert, A.; Siragusa, M.; Klatt, S.; Fleming, I.; Gunther, S.; Looso, M.; Brandes, R. P.; Langer, H. F.; Papapetropoulos, A.; Singhal, M.; Schulz, M. H.; Plass, C.; Heineke, J.; Dobreva, G.; Hu, J.; Bibli, S.-I.: Cystine import and oxidative catabolism fuel vascular growth and repair via nutrient-responsive histone acetylation. CELL METABOLISM 38 (1) (2026)

Zhou, X.; Kuenne, C.; Gunther, S.; Wittig, I.; Guven, B.; Boutguetait, D.; Delgado Lagos, F.; Sachs, N.; Maegdefessel, L.; Muller, O. J. et al.; Munch, C.; Offermanns, S.; Fleming, I.; Siragusa, M.: Nuclear eNOS Interacts With and S-Nitrosates ADAR1 to Modulate Type I Interferon Signaling and Endothelial Function. CIRCULATION 152 (25) (2025)

Herrle, N.; Malacarne, P. F.; Warwick, T.; Cabrera-Orefice, A.; Chen, Y.; Gheisari, M.; Chatterjee, S.; Leisegang, M. S.; Sarakpi, T.; Wionski, S. et al.; Lopez, M.; Kader, C.; Teichmann, T.; Drekolia, M.-K.; Koch, I.; Kessler, M.; Klein, S.; Erhard Uschner, F.; Trebicka, J.; Brunst, S.; Proschak, E.; Gunther, S.; Rosas-Lemus, M.; Baumgarten, N.; Klatt, S.; Speer, T.; Bibli, S.-I.; Segarra, M.; Acker-Palmer, A.; Wagner, J. U. G.; Wittig, I.; Dimmeler, S.; Schulz, M. H.; Richards, J. B.; Gilsbach, R.; Denton, T. T.; Fleming, I.; Hannibal, L.; Brandes, R. P.; Rezende, F.: The transaminase-ω-amidase pathway senses oxidative stress to control glutamine metabolism and α-ketoglutarate levels in endothelial cells. EMBO JOURNAL (2025)

Heck, C.; Zimmermann-Geller, B.; Haun, S.; Lotfering, F.; Welbrink, P.; Kursammer, D.; Frommer, K. W.; Arnold-Graf, M.; Korb-Pap, A.; Knothe, A. et al.; Schulz, N.; Simianer, S.; Tarner, I.; Hermann, W.; Biehl, C.; Gunther, S.; Steinmeyer, J.; Lips, K. S.; Rickert, M.; Rehart, S.; Muller-Ladner, U.; Neumann, E.: Influence of canstatin on fibroblast-driven hypervascularisation in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES 84 (12), S. 1968 - 1982 (2025)

Heck, C.; Zimmermann-Geller, B.; Haun, S.; Lotfering, F.; Welbrink, P.; Kursammer, D.; Frommer, K. W.; Arnold-Graf, M.; Korb-Pap, A.; Knothe, A. et al.; Schulz, N.; Simianer, S.; Tarner, I.; Hermann, W.; Biehl, C.; Gunther, S.; Steinmeyer, J.; Lips, K. S.; Rickert, M.; Rehart, S.; Muller-Ladner, U.; Neumann, E.: Influence of canstatin on fibroblast-driven hypervascularisation in rheumatoid arthritis. ANNALS OF THE RHEUMATIC DISEASES 84 (12), S. 1968 - 1982 (2025)

Mukherjee, D.; Larcher, V.; Winter, H.; Sachs, N.; Andriani, F.; Chiesa, M.; Perrucci, G. L.; Rega, S.; Gunther, S.; Kuenne, C. et al.; Martin, J. C.; Gu, Y.; Pelisek, J.; Fischer, A.; Peruzzo, S.; Pizzo, E.; Peterson, K. L.; Dimmeler, S.; Maegdefessel, L.; Cattaneo, P.; Evans, S. M.; Guimaraes-Camboa, N.: Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis. CARDIOVASCULAR RESEARCH (2025)

Huber, L. S.; Merline, R.; Zeng-Brouwers, J.; Vutukuri, R.; Kraus, N.; Ortiz, C.; Guenther, S.; Buhl, E. M.; Hahnefeld, L.; Gurke, R. et al.; Bein, J.; Karimova, M.; Wurzel, P.; Boor, P.; Welsch, C.; Wild, P.; Pfeilschifter, J.; Kogel, D.; Wygrecka, M.; Trebicka, J.; Bartoszewski, R.; Dikic, I.; Schaefer, L.: Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY 329 (5), S. C1360 - C1379 (2025)

Georgieva, A. M.; Sreenivasan, K.; Ding, D.; Villeneuve, C.; Wickstrom, S. A.; Gunther, S.; Kuenne, C.; Gartner, U.; Guo, X.; Zhou, Y. et al.; Yuan, X.; Braun, T.: Regulation of NSL by TAF4A is critical for genome stability and quiescence of muscle stem cells. NATURE COMMUNICATIONS 16 (1), 8726 (2025)

Wang, T.; Bonnavion, R.; Piesker, J.; Guenther, S.; Wettschureck, N.: GPRC5B preserves a mature j3 cell state in obesity by controlling MafA expression. JCI INSIGHT 10 (20), e194115 (2025)

Langschied, F.; Leisegang, M. S.; Guenther, S.; Hahner, F.; Brandes, R. P.; Ebersberger, I.: Loss of multiple micro-RNAs uncovers multi-level restructuring of gene regulation in rodents. BMC GENOMICS 26 (1), 800 (2025)

Shao, J.; Kwon, J.; Wang, T.; Guenther, S.; Tombor, L. S.; Warwick, T.; Shaheryar, Z.; Brandes, R. P.; Dimmeler, S.; Wenzel, J. et al.; Offermanns, S.; Schwaninger, M.; Wettschureck, N.: Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation. NATURE COMMUNICATIONS 16 (1), 6232 (2025)

Jafari, L.; Wiedenroth, C. B.; Kriechbaum, S. D.; Gruen, D.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Spaeth, A. M.; Cherian, A. V.; Troidl, C. et al.; Wilhelm, J.; Keranov, S.; Keller, T.; Kojonazarov, B.; Schermuly, R. T.; Guth, S.; Doerr, O.; Nef, H.; Boehm, M.; Spiekerkoetter, E.; Leszek, P.; Varga, Z. V.; Ferdinandy, P.; Ghofrani, H. A.; Dorfmueller, P.; Weissmann, N.; Hamm, C. W.; Mayer, E.; Seeger, W.; Liebetrau, C.; Pullamsetti, S. S.: Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery. NATURE CARDIOVASCULAR RESEARCH 4 (7) (2025)

Gajawada, P.; Guenther, S.; Rolf, A.; Nabhanizadeh, J.; Savai, R.; Choi, Y.-H.; Richter, M.: Transcriptomic profiling of granuloma in patients with cardiac sarcoidosis. THERANOSTICS 15 (13), S. 6044 - 6057 (2025)

Constanty, F.; Wu, B.; Wei, K.-H.; Lin, I.-T.; Dallmann, J.; Guenther, S.; Lautenschlaeger, T.; Priya, R.; Lai, S.-L.; Stainier, D. Y. R. et al.; Beisaw, A.: Border-zone cardiomyocytes and macrophages regulate extracellular matrix remodeling to promote cardiomyocyte protrusion during cardiac regeneration. NATURE COMMUNICATIONS 16 (1), 3823 (2025)

Panza, P.; Kim, H.-T.; Lautenschlaeger, T.; Piesker, J.; Guenther, S.; Alayoubi, Y.; Cleaver, O.; Looso, M.; Stainier, D. Y. R.: The lung microvasculature promotes alveolar type 2 cell differentiation via secreted SPARCL1. STEM CELL REPORTS 20 (4), 102451 (2025)

Gupta, S.; Bajwa, G. K.; El-Sammak, H.; Mattonet, K.; Guenther, S.; Looso, M.; Stainier, D. Y. R.; Marin-Juez, R.: The transmembrane glycoprotein Gpnmb is required for the immune and fibrotic responses during zebrafish heart regeneration. DEVELOPMENTAL BIOLOGY 521, S. 153 - 162 (2025)

Kwon, J.; Haruya, K.; Mattonet, K.; Guenther, S.; Hahnefeld, L.; Shamsara, J.; Heering, J.; Kurz, M.; Kirchhofer, S.; Krasel, C. et al.; Ulrich, M.; Persechino, M.; Murthy, S.; Orlandi, C.; Sadik, C. D.; Geisslinger, G.; Buenemann, M.; Kolb, P.; Offermanns, S.; Wettschureck, N.: Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling. NATURE COMMUNICATIONS 16 (1), 1448 (2025)

Lingampally, A.; Truchi, M.; Mauduit, O.; Delcroix, V.; Vasquez-Pacheco, E.; Gautier-Isola, M.; Chu, X.; Khadim, A.; Chao, C.-M.; Zabihi, M. et al.; Taghizadeh, S.; Rivetti, S.; Marega, M.; Moiseenko, A.; Hadzic, S.; Vazquez-Armendariz, A. I.; Herold, S.; Guenther, S.; Millar-Buechner, P.; Koepke, J.; Samakovlis, C.; Wilhelm, J.; Bartkuhn, M.; Braun, T.; Weissmann, N.; Zhang, J.; Wygrecka, M.; Makarenkova, H. P.; Guenther, A.; Seeger, W.; Chen, C.; El Agha, E.; Mari, B.; Bellusci, S.: Evidence for a lipofibroblast-to-Cthrc1+ myofibroblast reversible switch during the development and resolution of lung fibrosis in young mice. EUROPEAN RESPIRATORY JOURNAL 65 (2), 2300482 (2025)

Jin, Y.-J.; Liang, G.; Li, R.; Wang, S.; Alnouri, M. W.; Bentsen, M.; Kuenne, C.; Guenther, S.; Yan, Y.; Li, Y. et al.; Wettschureck, N.; Offermanns, S.: Phosphorylation of endothelial histone H3.3 serine 31 by PKN1 links flow-induced signaling to proatherogenic gene expression. NATURE CARDIOVASCULAR RESEARCH 4 (2) (2025)