Publikationen von Remy Bonnavion

Chen, X.; Shao, J.; Brandenburger, I.; Qian, W.; Hahnefeld, L.; Bonnavion, R.; Cho, H.; Wang, S.; Hidalgo, J.; Wettschureck, N. et al.; Geisslinger, G.; Gurke, R.; Wang, Z.; Offermanns, S.: FFAR4-mediated IL-6 release from islet macrophages promotes insulin secretion and is compromised in type-2 diabetes. NATURE COMMUNICATIONS 16 (1), 3422 (2025)

Cho, H.; Lai, C.-C.; Bonnavion, R.; Alnouri, M. W.; Wang, S.; Roquid, K. A.; Kawase, H.; Campos, D.; Chen, M.; Weinstein, L. S. et al.; Martinez, A.; Looso, M.; Sanda, M.; Offermanns, S.: Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes. SCIENCE 387 (6734), S. 674 - 682 (2025)

Cho, H.; Lai, C.-C.; Bonnavion, R.; Alnouri, M. W.; Wang, S.; Roquid, K. A.; Kawase, H.; Campos, D.; Chen, M.; Weinstein, L. S. et al.; Martinez, A.; Looso, M.; Sanda, M.; Offermanns, S.: Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes. SCIENCE 387 (6734), S. 674 - 682 (2025)

Alnouri, M. W.; Roquid, K. A.; Bonnavion, R.; Cho, H.; Heering, J.; Kwon, J.; Jaeger, Y.; Wang, S.; Guenther, S.; Wettschureck, N. et al.; Geisslingerb, G.; Gurke, R.; Mueller, C. E.; Proschak, E.; Offermanns, S.: SPMs exert anti- inflammatory and pro- resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 121 (41), e2407130121 (2024)

Bonnavion, R.; Liu, S.; Kawase, H.; Roquid, K. A.; Offermanns, S.: Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5). FRONTIERS IN PHARMACOLOGY 14, 1297596 (2023)

Li, R.; Shao, J.; Jin, Y. J.; Haruya, K.; Ong, Y. T.; Troidl, K.; Quan, Q.; Wang, L.; Bonnavion, R.; Wietelmann, A. et al.; Helmbacher , F.; Potente, M.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Endothelial FAT1 inhibits angiogenesis by controlling YAP/TAZ protein degradation via E3 ligase MIB2. NATURE COMMUNICATIONS 14 (1), 1980 (2023)

Vieira, J. R.; Shah, B.; Dupraz, S.; Paredes, I.; Himmels, P.; Schermann, G.; Adler, H.; Motta, A.; Gaertner, L.; Navarro-Aragall, A. et al.; Ioannou, E.; Dyukova, E.; Bonnavion, R.; Fischer, A.; Bonanomi, D.; Bradke, F.; Ruhrberg, C.; de Almodovar, C. R.: Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development. NEURON 110 (24), S. 4074 - 4089.e6 (2022)

Gurusamy, M.; Tischner, D.; Shao, J.; Klatt, S.; Zukunft, S.; Bonnavion, R.; Guenther, S.; Siebenbrodt, K.; Kestner, R.-I.; Kuhlmann, T. et al.; Fleming, I.; Offermanns, S.; Wettschureck, N.: G-protein-coupled receptor P2Y10 facilitates chemokine-induced CD4 T cell migration through autocrine/paracrine mediators. NATURE COMMUNICATIONS 12 (1), 6798 (2021)

Le Mercier, A.; Bonnavion, R.; Yu, W.; Alnouri, M. W.; Ramas, S.; Zhang, Y.; Jaeger, Y.; Roquid, K. A.; Jeong, H.-W.; Sivaraj, K. K. et al.; Cho, H.; Chen, X.; Strilic, B.; Sijmonsma, T.; Adams, R.; Schroeder, T.; Rieger, M. A.; Offemanns, S.: GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 118 (17), e2021596118 (2021)

Teinturier, R.; Luo, Y.; Decaussin-Petrucci, M.; Vlaeminck-Guillem, V.; Vacherot, F.; Firlej, V.; Bonnavion, R.; Abou Ziki, R.; Gherardi, S.; Goddard, I. et al.; Gadot, N.; Bertolino, P.; Le Romancer, M.; Zhang, C. X.: Men1 disruption in Nkx3.1-deficient mice results in AR(low)/CD44(+) microinvasive carcinoma development with the dysregulated AR pathway. ONCOGENE (2020)

Kwon, H.-B.; Mackie I, D.; Bonnavion, R.; Le Mercier, A.; Helker, C. S. M.; Son, T.; Guenter, S.; Serafin, D. S.; Kim, K.-W.; Offermanns, S. et al.; Caron, K. M.; Stainier, D. Y. R.: The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE 3 (4), S. 676 - 689 (2020)

Chennupati, R.; Wirth, A.; Favre, J.; Li, R.; Bonnavion, R.; Jin, Y.-J.; Wietelmann, A.; Schweda, F.; Wettschureck, N.; Henrion, D. et al.; Offermanns, S.: Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance. ELIFE 8, e49374 (2019)

Helker, C. S. M.; Mullapudi, S.-T.; Mueller, L. M.; Preussner, J.; Tunaru, S.; Skog, O.; Kwon, H.-B.; Kreuder, F.; Lancman, J. J.; Bonnavion, R. et al.; Dong, P. D. S.; Looso, M.; Offermanns, S.; Korsgren, O.; Spagnoli, F. M.; Stainier, D. Y. R.: A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development. DEVELOPMENT 146 (14), UNSP dev172569 (2019)

Tunaru, S.; Bonnavion, R.; Brandenburger, I.; Preussner, J.; Thomas, D.; Scholich, K.; Offermanns, S.: 20-HETE promotes glucose-stimulated insulin secretion in an autocrine manner through FFAR1. NATURE COMMUNICATIONS 9, 177 (2018)