Publikationen von Carsten Kuenne

Siragusa, M.; Graumann, J.; Kuenne, C.; Gunther, S.; Jeratsch, S.; Guven, B.; Susser, S.; Talyan, S.; Bezuneh, B.; Matthess, Y. et al.; Cartura, M.; Zhou, X.; Cho, H.; Sachs, N.; Maegdefessel, L.; Muller, O. J.; Troidl, C.; Nef, H. M.; Looso, M.; Kaulich, M.; Offermanns, S.; Fleming, I.: Identification of unannotated microproteins involved in endothelial cell homeostasis, dysfunction, and vascular disease. CARDIOVASCULAR RESEARCH (2026)

Thurner, L.; Fadle, N.; Thurner, B.; Kos, I. A.; Bewarder, M.; Regitz, E.; Bette, B.; Fischer, Y.; Lesan, V.; Rixecker, T. et al.; Hoffmann, M.-C.; Preuss, K.-D.; Schormann, C.; Kaddu-Mulindwa, D.; Roemer, K.; Cetin, O.; Mang, S.; Becker, A.; Seiler, F.; Herr, C.; Lensch, C.; Lehmann, J.; Thiel-Bodenstaff, A.; Link, A.; Werner, C.; Wuchter, P.; Korper, S.; Pfuhl, T.; Lohse, S.; Rissland, J.; Thieser, K.; Pilch, J.; Papan, C.; Roth, S.; Vehreschild, J. J.; Scherer, M.; Brohl, I.; Wagner, P.; Witzenrath, M.; Thibeault, C.; Haack, I. a.; Mitrov, L.; Putz, S. M.; Reese, J.-P.; Krawczak, M.; Hamelmann, E.; Kopfnagel, V.; Fiedler, K.; Geisler, R.; Valentin, H.; Stahl, D.; Hanss, S.; Ameling, S.; Volker, U.; Hansch, S.; Dorr, M.; Blaschke, S.; Braunsteiner, J.; Dahl, E.; Pape, D.; Petersmann, A.; Stilgenbauer, S.; Bloos, F.; Schrezenmeier, H.; Langer, F.; Gabelein, G.; Friesenhahn-Ochs, B.; Pfeifer, J.; Bauer, M.; Becker, S. L.; Neumann, F.; Bohm, M.; Anton, G.; Kuenne, C.; Pullamsetti, S. S.; Looso, M.; Bals, R.; Smola, S.; Meybohm, P.; Krawczyk, M.; Lepper, P. M.; Kessel, C.: Autoantibodies to IL-1Ra and PGRN in severe COVID-19 are associated with inflammation-induced hyperphosphorylated antigen isoforms. NATURE COMMUNICATIONS 17 (1), 4768 (2026)

Leberzammer, J.; Abplanalp, W. T.; Grikscheit, K.; Solomonidis, E. G.; Glaser, S.-F.; Schuhmacher, B.; Merten, M.; Jeremijev, G.; Wilken-Schmitz, A.; Korth, L. et al.; John, D.; Gunther, S.; Kuenne, C.; Looso, M.; Valasarajan, C.; Benes, V.; Jung, F.; Niehaus, V.; Anton, G.; Stellbrink, C.; Rommele, C.; Gopel, S.; Pullamsetti, S. S.; Vehreschild, J.; Vehreschild, M.; Ciesek, S.; Leistner, D. M.; Zeiher, A. M.; Dimmeler, S.; Cremer, S.: Atherosclerosis licenses for an exceeding immune response in COVID-19 disease by interferon priming in circulating myeloid cells. CARDIOVASCULAR RESEARCH (2026)

Zhou, X.; Kuenne, C.; Gunther, S.; Wittig, I.; Guven, B.; Boutguetait, D.; Delgado Lagos, F.; Sachs, N.; Maegdefessel, L.; Muller, O. J. et al.; Munch, C.; Offermanns, S.; Fleming, I.; Siragusa, M.: Nuclear eNOS Interacts With and S-Nitrosates ADAR1 to Modulate Type I Interferon Signaling and Endothelial Function. CIRCULATION 152 (25) (2025)

Mukherjee, D.; Larcher, V.; Winter, H.; Sachs, N.; Andriani, F.; Chiesa, M.; Perrucci, G. L.; Rega, S.; Gunther, S.; Kuenne, C. et al.; Martin, J. C.; Gu, Y.; Pelisek, J.; Fischer, A.; Peruzzo, S.; Pizzo, E.; Peterson, K. L.; Dimmeler, S.; Maegdefessel, L.; Cattaneo, P.; Evans, S. M.; Guimaraes-Camboa, N.: Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis. CARDIOVASCULAR RESEARCH (2025)

Georgieva, A. M.; Sreenivasan, K.; Ding, D.; Villeneuve, C.; Wickstrom, S. A.; Gunther, S.; Kuenne, C.; Gartner, U.; Guo, X.; Zhou, Y. et al.; Yuan, X.; Braun, T.: Regulation of NSL by TAF4A is critical for genome stability and quiescence of muscle stem cells. NATURE COMMUNICATIONS 16 (1), 8726 (2025)

Jan, D.; Brenton, B.; Bentsen, M.; Kuenne, C.; Looso, M.: PEAKQC: periodicity evaluation in single-cell ATAC-seq data for quality assessment. BRIEFINGS IN BIOINFORMATICS 26 (5), bbaf465 (2025)

Jafari, L.; Wiedenroth, C. B.; Kriechbaum, S. D.; Gruen, D.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Spaeth, A. M.; Cherian, A. V.; Troidl, C. et al.; Wilhelm, J.; Keranov, S.; Keller, T.; Kojonazarov, B.; Schermuly, R. T.; Guth, S.; Doerr, O.; Nef, H.; Boehm, M.; Spiekerkoetter, E.; Leszek, P.; Varga, Z. V.; Ferdinandy, P.; Ghofrani, H. A.; Dorfmueller, P.; Weissmann, N.; Hamm, C. W.; Mayer, E.; Seeger, W.; Liebetrau, C.; Pullamsetti, S. S.: Transcriptional changes of the extracellular matrix in chronic thromboembolic pulmonary hypertension govern right ventricle remodeling and recovery. NATURE CARDIOVASCULAR RESEARCH 4 (7) (2025)

Jin, Y.-J.; Liang, G.; Li, R.; Wang, S.; Alnouri, M. W.; Bentsen, M.; Kuenne, C.; Guenther, S.; Yan, Y.; Li, Y. et al.; Wettschureck, N.; Offermanns, S.: Phosphorylation of endothelial histone H3.3 serine 31 by PKN1 links flow-induced signaling to proatherogenic gene expression. NATURE CARDIOVASCULAR RESEARCH 4 (2) (2025)

Zhou, L.; Pereiro, M. T.; Li, Y.; Derigs, M.; Kuenne, C.; Hielscher, T.; Huang, W.; Kraenzlin, B.; Tian, G.; Kobayashi, K. et al.; Lu, G.-H. N.; Roedl, K.; Schmidt, C.; Guenther, S.; Looso, M.; Huber, J.; Xu, Y.; Wiech, T.; Sperhake, J.-P.; Wichmann, D.; Groene, H.-J.; Worzfeld, T.: Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury. SCIENCE TRANSLATIONAL MEDICINE 16 (767), eadk5005 (2024)

Vega-Sendino, M.; Luettmann, F. F.; Olbrich, T.; Chen, Y.; Kuenne, C.; Stein, P.; Tillo, D.; Carey, G. I.; Zhong, J.; Savy, V. et al.; Radonova, L.; Lu, T.; Saykali, B.; Kim, K.-P.; Domingo, C. N.; Schueler, L.; Guenther, S.; Bentsen, M.; Bosnakovski, D.; Schoeler, H.; Kyba, M.; Maity, T. K.; Jenkins, L. M.; Looso, M.; Williams, C. J.; Kim, J.; Ruiz, S.: The homeobox transcription factor DUXBL controls exit from totipotency. NATURE GENETICS (56), S. 697 - 709 (2024)

Torres, L. D. H.; Rezende, F.; Peschke, E.; Will, O.; Hoevener, J.-B.; Spiecker, F.; Oezorhan, U.; Lampe, J.; Stoelting, I.; Aherrahrou, Z. et al.; Kuenne, C.; Kusche-Vihrog, K.; Matschl, U.; Hille, S.; Brandes, R. P.; Schwaninger, M.; Mueller, O. J.; Raasch, W.: Incidence of microvascular dysfunction is increased in hyperlipidemic mice, reducing cerebral blood flow and impairing remote memory. FRONTIERS IN ENDOCRINOLOGY 15, 1338458 (2024)

Albu, M.; Affolter, E.; Gentile, A.; Xu, Y.; Kikhi, K.; Howard, S.; Kuenne, C.; Priya, R.; Gunawan, F.; Stainier, D. Y. R.: Distinct mechanisms regulate ventricular and atrial chamber wall formation. NATURE COMMUNICATIONS 15 (1), 8159 (2024)

Wu, F.; Li, X.; Looso, M.; Liu, H.; Ding, D.; Guenther, S.; Kuenne, C.; Liu, S.; Weissmann, N.; Boettger, T. et al.; Atzberger, A.; Kolahian, S.; Renz, H.; Offermanns, S.; Gaertner, U.; Potente, M.; Zhou, Y.; Yuan, X.; Braun, T.: Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine. NATURE GENETICS 55 (1), S. 100 - + (2024)

Li, X.; Wu, F.; Guenther, S.; Looso, M.; Kuenne, C.; Zhang, T.; Wiesnet, M.; Klatt, S.; Zukunft, S.; Fleming, I. et al.; Poschet, G.; Wietelmann, A.; Atzberger, A.; Potente, M.; Yuan, X.; Braun, T.: Inhibition of fatty acid oxidation enables heart regeneration in adult mice. NATURE (2023)

Khassafi, F.; Chelladurai, P.; Valasarajan, C.; Nayakanti, S. R.; Martineau, S.; Sommer, N.; Yokokawa, T.; Boucherat, O.; Kamal, A.; Kiely, D. G. et al.; Swift, A. J.; Alabed, S.; Omura, J.; Breuils-Bonnet, S.; Kuenne, C.; Potus, F.; Guenther, S.; Savai, R.; Seeger, W.; Looso, M.; Zaugg, J. B.; Tello, K.; Provencher, S.; Bonnet, S.; Pullamsetti, S. S.: Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension. NATURE CARDIOVASCULAR RESEARCH 2 (10), S. 917 - + (2023)

Karger, A.; Mansouri, S.; Leisegang , M. S.; Weigert, A.; Guenther, S.; Kuenne, C.; Wittig , I.; Zukunft , S.; Klatt , S.; Aliraj , B. et al.; Klotz V , L.; Winter , H.; Mahavadi, P.; Fleming , I.; Ruppert , C.; Witte , B.; Alkoudmani , I.; Gattenloehner, S.; Grimminger, F.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: ADPGK-AS1 long noncoding RNA switches macrophage metabolic and phenotypic state to promote lung cancer growth. EMBO JOURNAL (2023)

Zheng, X.; Sarode, P.; Weigert , A.; Turkowski, K.; Chelladurai, P.; Guenther, S.; Kuenne, C.; Winter , H.; Stenzinger, A.; Reu, S. et al.; Grimminger, F.; Stiewe, T.; Seeger, W.; Pullamsetti, S. S.; Savai, R.: The HDAC2-SP1 Axis Orchestrates Protumor Macrophage Polarization. CANCER RESEARCH 83 (14), S. 2345 - 2357 (2023)

Nayakanti, S. R.; Friedrich, A.; Sarode, P.; Jafari, L.; Maroli, G.; Boehm, M.; Bourgeois, A.; Grobs, Y.; Khassafi, F.; Kuenne, C. et al.; Guenther, S.; Dabral, S.; Wilhelm, J.; Weiss, A.; Wietelmann, A.; Kojonazarov, B.; Janssen, W.; Looso, M.; de Man, F.; Provencher, S.; Tello, K.; Seeger, W.; Bonnet, S.; Savai, R.; Schermuly, R.; Pullamsetti, S. S.: Targeting Wnt-ss-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling. CIRCULATION RESEARCH 132 (11), S. 1468 - 1485 (2023)

Boonsanay, B.; Mosa, M. H.; Looso, M.; Weichenhan, D.; Ceteci, F.; Pudelko, L.; Lechel, A.; Michel, C. S.; Kuenne, C.; Farin, H. F. et al.; Plass, C.; Greten, F. R.: Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression. GASTROENTEROLOGY 164 (2), S. 214 - 227 (2023)