Biomolekulare Massenspektrometrie

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Using the toolkit of quantitative shotgun proteomics, the Scientific Service Group Biomolecular Mass Spectrometry at the Max Planck Institute for Heart and Lung Research offers collaborative support to the design, execution and analysis of projects based on the characterization of complex protein mixtures and posttranslational modifications.

Application examples (ordered by increasing complexity of the mixture analyzed and data derived) include, but are not restricted to

• the identification of specifically enriched proteins in (immuno)affinity purification experiments

• expression–proteomic comparison of mutant and wild type or treatment and control experimental designs, as well as

• global phosphoproteomic analysis using a workflow optimized for small amounts of input material.

 

We aim to empower collaborators in interpreting data derived from their experiments and provide reporting surpassing the plain provisioning of raw identification/quantitation data derived from mass spectrometrical information. Using a common denominator set of analytical approaches, our reporting combines documentation of sample preparation and mass spectrometric analysis with a first pass bioinformatic analysis.

We are always looking to support exciting science with our expertise in proteomics and protein biochemistry in general. For a discussion of your experimental needs, plans and ideas, reach out to us using the contact information below.

Data collection and consecutive analysis: The service group closely collaborates with the scientists.
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