Publications of Stefan Offermanns

Ishihama, S.; Yoshida, S.; Yoshida, T.; Mori, Y.; Ouchi, N.; Eguchi, S.; Sakaguchi, T.; Tsuda, T.; Kato, K.; Shimizu, Y. et al.; Ohashi, K.; Okumura, T.; Bando, Y. K.; Yagyu, H.; Wettschureck, N.; Kubota, N.; Offermanns, S.; Kadowaki, T.; Murohara, T.; Takefuji, M.: LPL/AQP7/GPD2 promotes glycerol metabolism under hypoxia and prevents cardiac dysfunction during ischemia. FASEB JOURNAL 35 (12), e22048 (2021)

Jin, Y.-J.; Chennupati, R.; Li, R.; Liang, G.; Wang, S.; Iring, A.; Graumann, J.; Wettschureck, N.; Offermanns, S.: Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation. JOURNAL OF CLINICAL INVESTIGATION 131 (21), e145734 (2021)

Alexander, S. P. H.; Christopoulos, A.; Davenport, A. P.; Kelly, E.; Mathie, A.; Peters, J. A.; Veale, E. L.; Armstrong, J. F.; Faccenda, E.; Harding, S. D. et al.; Pawson, A. J.; Southan, C.; Davies, J. A.; Abbracchio, M. P.; Alexander, W.; Al-hosaini, K.; Baeck, M.; Barnes, N. M.; Bathgate, R.; Beaulieu, J.-M.; Bernstein, K. E.; Bettler, B.; Birdsall, N. J. M.; Blaho, V.; Boulay, F.; Bousquet, C.; Braeuner-Osborne, H.; Burnstock, G.; Calo, G.; Castano, J. P.; Catt, K.; Ceruti, S.; Chazot, P.; Chiang, N.; Chini, B.; Chun, J.; Cianciulli, A.; Civelli, O.; Clapp, L. H.; Couture, R.; Csaba, Z.; Dahlgren, C.; Dent, G.; Singh, K. D.; Douglas, S. D.; Dournaud, P.; Eguchi, S.; Escher, E.; Filardo, E. J.; Fong, T.; Fumagalli, M.; Gainetdinov, R. R.; de Gasparo, M.; Gerard, C.; Gershengorn, M.; Gobeil, F.; Goodfriend, T. L.; Goudet, C.; Gregory, K. J.; Gundlach, A. L.; Hamann, J.; Hanson, J.; Hauger, R. L.; Hay, D. L.; Heinemann, A.; Hollenberg, M. D.; Holliday, N. D.; Horiuchi, M.; Hoyer, D.; Hunyady, L.; Husain, A.; IJzerman, A. P.; Inagami, T.; Jacobson, K. A.; Jensen, R. T.; Jockers, R.; Jonnalagadda, D.; Karnik, S.; Kaupmann, K.; Kemp, J.; Kennedy, C.; Kihara, Y.; Kitazawa, T.; Kozielewicz, P.; Kreienkamp, H.-J.; Kukkonen, J. P.; Langenhan, T.; Leach, K.; Lecca, D.; Lee, J. D.; Leeman, S. E.; Leprince, J.; Li, X. X.; Williams, T. L.; Lolait, S. J.; Lupp, A.; Macrae, R.; Maguire, J.; Mazella, J.; McArdle, C. A.; Melmed, S.; Michel, M. C.; Miller, L. J.; Mitolo, V.; Mouillac, B.; Mueller, C. E.; Murphy, P.; Nahon, J.-L.; Ngo, T.; Norel, X.; Nyimanu, D.; Ocarroll, A.-M.; Offermanns, S.; Panaro, M. A.; Parmentier, M.; Pertwee, R. G.; Pin, J.-P.; Prossnitz, E. R.; Quinn, M.; Ramachandran, R.; Ray, M.; Reinscheid, R. K.; Rondard, P.; Rovati, G. E.; Ruzza, C.; Sanger, G. J.; Schoeneberg, T.; Schulte, G.; Schulz, S.; Segaloff, D. L.; Serhan, C. N.; Stoddart, L. A.; Sugimoto, Y.; Summers, R.; Tan, V. P.; Thal, D.; Thomas, W. (.; Timmermans, P. M. W. M.; Tirupula, K.; Tulipano, G.; Unal, H.; Unger, T.; Valant, C.; Vanderheyden, P.; Vaudry, D.; Vaudry, H.; Vilardaga, J.-P.; Walker, C. S.; Wang, J. M.; Ward, D. T.; Wester, H.-J.; Willars, G. B.; Woodruff, T. M.; Yao, C.; Ye, R. D.: THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors. BRITISH JOURNAL OF PHARMACOLOGY 178 (Supplement 1), pp. S27 - S156 (2021)

Berillo, O.; Coelho, S. C.; Mahjoub, N.; Offermanns, S.; Paradis, P.; Schiffrin, E. L.: Aldosterone contributes to hypertension in malemice inducibly overexpressing human endothelin-1 in endothelium. JOURNAL OF HYPERTENSION 39 (9), pp. 1908 - 1917 (2021)

Grunddal, K. V.; Tonack, S.; Egerod, K. L.; Thompson, J. J.; Petersen, N.; Engelstoft, M. S.; Vagne, C.; Keinse, C.; Gradwohl, G.; Offermanns, S. et al.; Schwartz, T. W.: Adhesion receptor ADGRG2/GPR64 is in the GI-tract selectively expressed in mature intestinal tuft cells. MOLECULAR METABOLISM 51, 101231 (2021)

Le Mercier, A.; Bonnavion, R.; Yu, W.; Alnouri, M. W.; Ramas, S.; Zhang, Y.; Jaeger, Y.; Roquid, K. A.; Jeong, H.-W.; Sivaraj, K. K. et al.; Cho, H.; Chen, X.; Strilic, B.; Sijmonsma, T.; Adams, R.; Schroeder, T.; Rieger, M. A.; Offemanns, S.: GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 118 (17), e2021596118 (2021)

Molnar, P. J.; Der, B.; Borsodi, K.; Balla, H.; Borbas, Z.; Molnar, K.; Ruisanchez, E.; Kenessey, I.; Horvath, A.; Keszthelyi, A. et al.; Majoros, A.; Nyirady, P.; Offermanns, S.; Benyo, Z.: Isoprostanes evoke contraction of the murine and human detrusor muscle via activation of the thromboxane prostanoid TP receptor and Rho kinase. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 320 (4), pp. F537 - F547 (2021)

Simonetti, M.; Paldy, E.; Njoo, C.; Bali, K. K.; Worzfeld, T.; Pitzer, C.; Kuner, T.; Offermanns, S.; Mauceri, D.; Kuner, R.: The impact of Semaphorin 4C/Plexin-B2 signaling on fear memory via remodeling of neuronal and synaptic morphology. MOLECULAR PSYCHIATRY 26 (4), pp. 1376 - 1398 (2021)

Bibli, S.-I.; Hu, J.; Looso, M.; Weigert, A.; Ratiu, C.; Wittig, J.; Drekolia, M. K.; Tombor, L.; Randriamboavonjy, V.; Leisegang, M. S. et al.; Goymann, P.; Lagos, F. D.; Fisslthaler, B.; Zukunft, S.; Kyselova, A.; Justo, A. F. O.; Heidler, J.; Tsilimigras, D.; Brandes, R. P.; Dimmeler, S.; Papapetropoulos, A.; Knapp, S.; Offermanns, S.; Wittig, I.; Nishimura, S. L.; Sigala, F.; Fleming, I.: Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function. CIRCULATION 143 (9), pp. 935 - 948 (2021)

Bibli, S.-I.; Hu, J.; Looso, M.; Weigert, A.; Ratiu, C.; Wittig, J.; Drekolia, M. K.; Tombor, L.; Randriamboavonjy, V.; Leisegang, M. S. et al.; Goymann, P.; Lagos, F. D.; Fisslthaler, B.; Zukunft, S.; Kyselova, A.; Justo, A. F. O.; Heidler, J.; Tsilimigras, D.; Brandes, R. P.; Dimmeler, S.; Papapetropoulos, A.; Knapp, S.; Offermanns, S.; Wittig, I.; Nishimura, S. L.; Sigala, F.; Fleming, I.: Mapping the Endothelial Cell S-Sulfhydrome Highlights the Crucial Role of Integrin Sulfhydration in Vascular Function. CIRCULATION 143 (9), pp. 935 - 948 (2021)

Jiang, C.; Javed, A.; Kaiser, L.; Nava, M. M.; Xu, R.; Brandt, D. T.; Zhao, D.; Mayer, B.; Fernandez-Baldovinos, J.; Zhou, L. et al.; Hoess, C.; Sawmynaden, K.; Oleksy, A.; Matthews, D.; Weinstein, L. S.; Hahn, H.; Groene, H.-J.; Graumann, P. L.; Niessen, C. M.; Offermanns, S.; Wickstroem, S. A.; Worzfeld, T.: Mechanochemical control of epidermal stem cell divisions by B-plexins. NATURE COMMUNICATIONS 12 (1), 1308 (2021)

Dubrall, D.; Pflock, R.; Kosinska, J.; Schmid, M.; Bleich, M.; Himmerkus, N.; Offermanns, S.; Schwaninger, M.; Sachs, B.: Do dimethyl fumarate and nicotinic acid elicit common, potentially HCA(2)-mediated adverse reactions? A combined epidemiological-experimental approach. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2021)

Lopez, M.; Malacarne, P. F.; Gajos-Draus, A.; Ding, X.; Daiber, A.; Lundberg, J. O.; Offermanns, S.; Brandes, R. P.; Rezende, F.: Vascular biotransformation of organic nitrates is independent of cytochrome P450 monooxygenases. BRITISH JOURNAL OF PHARMACOLOGY 178 (7), pp. 1495 - 1506 (2021)

Wang, L.; Chennupati, R.; Jin, Y.-J.; Li, R.; Wang, S.; Guenther, S.; Offermanns, S.: YAP/TAZ Are Required to Suppress Osteogenic Differentiation of Vascular Smooth Muscle Cells. ISCIENCE 23 (12), 101860 (2020)

Nakayama, A.; Albarran-Juarez, J.; Liang, G.; Roquid, K. A.; Iring, A.; Tonack, S.; Chen, M.; Mueller, O. J.; Weinstein, L. S.; Offermanns, S.: Disturbed flow-induced G(s)-mediated signaling protects against endothelial inflammation and atherosclerosis. JCI INSIGHT 5 (23), e140485 (2020)

Horimatsu, T.; Blomkalns, A. L.; Ogbi, M.; Moses, M.; Kim, D.; Patel, S.; Gilreath, N.; Reid, L.; Benson, T. W.; Pye, J. et al.; Ahmadieh, S.; Thompson, A.; Robbins, N.; Mann, A.; Edgell, A.; Benjamin, S.; Stansfield, B. K.; Huo, Y.; Fulton, D. J.; Agarwal, G.; Singh, N.; Offermanns, S.; Weintraub, N. L.; Kim, H. W.: Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD(+)/nicotinamide. CARDIOVASCULAR RESEARCH 116 (14), pp. 2226 - 2238 (2020)

Wang, L.; Wang, S.; Shi, Y.; Li, R.; Guenther, S.; Ong, Y. T.; Potente, M.; Yuan, Z.; Liu, E.; Offermanns, S.: YAP and TAZ protect against white adipocyte cell death during obesity. NATURE COMMUNICATIONS 11 (1), 5455 (2020)

Blankenbach, K. V.; Claas, R. F.; Aster, N. J.; Spohner, A. K.; Trautmann, S.; Ferreiros, N.; Black, J. L.; Tesmer, J. J. G.; Offermanns, S.; Wieland, T. et al.; Meyer zu Heringdorf, D.: Dissecting G(q/11)-Mediated Plasma Membrane Translocation of Sphingosine Kinase-1. CELLS 9 (10), 2201 (2020)

Kwon, H.-B.; Mackie I, D.; Bonnavion, R.; Le Mercier, A.; Helker, C. S. M.; Son, T.; Guenter, S.; Serafin, D. S.; Kim, K.-W.; Offermanns, S. et al.; Caron, K. M.; Stainier, D. Y. R.: The Orphan G-Protein Coupled Receptor 182 Is a Negative Regulator of Definitive Hematopoiesis through Leukotriene B4 Signaling. ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE 3 (4), pp. 676 - 689 (2020)

Li, M.; Nishio, S.-y.; Naruse, C.; Riddell, M.; Sapski, S.; Katsuno, T.; Hikita, T.; Mizapourshafiyi, F.; Smith, F. M.; Cooper, L. T. et al.; Lee, M. G.; Asano, M.; Boettger, T.; Krueger, M.; Wietelmann, A.; Graumann, J.; Day, B. W.; Boyd, A. W.; Offermanns, S.; Kitajiri, S.-i.; Usami, S.-i.; Nakayama, M.: Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome. NATURE COMMUNICATIONS 11 (1), 1343 (2020)