Lectures and additional information
Vertebrate Organ Development: The Zebrafish Heart
Lecture on iBiology.org
The lecture provides an overview about how a fertilized egg develops into a complex multicellular organism such as a fly, mouse or human. Didier Stainier explains that zebrafish are an excellent model organism in which to address this question because their eggs are externally fertilized, they produce many offspring and the embryos and larvae are translucent. Taking advantage of these characteristics, Stainier and his colleagues performed large forward genetic screens to look for mutants in zebrafish heart development. Their findings provide insight into the evolution and development of the vertebrate heart.