Vorträge und weiterführende Informationen

Vertebrate Organ Development: The Zebrafish Heart

Lecture on iBiology.org

The lecture provides an overview about how a fertilized egg develops into a complex multicellular organism such as a fly, mouse or human. Didier Stainier explains that zebrafish are an excellent model organism in which to address this question because their eggs are externally fertilized, they produce many offspring and the embryos and larvae are translucent. Taking advantage of these characteristics, Stainier and his colleagues performed large forward genetic screens to look for mutants in zebrafish heart development.  Their findings provide insight into the evolution and development of the vertebrate heart.


Part I:    Vertebrate Organ Development:  The Zebrafish Heart

Part II:   Cardiac Trabeculation

Part III:  Genetic Compensation

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