Postdoctoral Research Position and PhD Position (m/f/d) | Lung Development and Remodeling

Max-Planck-Institut für Herz- und Lungenforschung - W. G. Kerckhoff-Institut, Bad Nauheim

Art der Stelle

Wissenschaftlicher Nachwuchs

Developmental and Evolutionary Biology & Genetics Immunobiology and Infection Biology & Medicine Physiology

Ausschreibungsnummer: 2020_22

Stellenangebot vom 22. Oktober 2020

The Max Planck Institute for Heart and Lung Research in Bad Nauheim nearby Frankfurt (Germany) has one opening for a Postdoctoral Research Position (m/f/d) and PhD Position (m/f/d) (full-time, limited for 3 Years) in the field of cardiovascular and lung diseases (Ref. Nr. 2020_22). 

Job description

The Pullamsetti Group / Lung Vascular Epigenetics Group at the Max Planck Institute for Heart and Lung Research (MPI-HLR) in Bad Nauheim and Justus Liebig University (JLU) in Giessen is seeking a highly motivated postdoctoral research fellow and a PhD student to study transcriptional and epigenetic landscape underlying Pulmonary Hypertension, a chronic lung and cardiovascular disease.

Our groups aim is to develop novel treatment strategies for pulmonary hypertension, studying the epigenetic mechanisms, transcription factor networks, metabolic changes and cellular crosstalk with immune cells. Our international team offers an open, supportive, dynamic and motivating academic environment with excellent training opportunities. We use a wide spectrum of methods: cloning, cell culture, co cultures, precision cut lung slices, cell-based assays (proliferation, apoptosis, migration, invasion etc.), RNAseq, single-cell RNAseq, ChIP-seq, FACS, cardiovascular physiological measurements, imaging techniques (Echocardiography, MRI) and histomorphometric techniques.

In the following links you can find the publication and profile of the group:

https://www.ncbi.nlm.nih.gov/pubmed/?term=pullamsetti

https://mpi-hlr.de/forschung/abteilung-iv/ag-pullamsetti/

We are looking for enthusiastic and highly motivated applicants. For both positions, good knowledge of molecular and cellular biology approaches, and biological assays in general is essential. A demonstrated ability to communicate well, work within a team and maintain good laboratory records are also expected.

Essential requirements for Postdoctoral position applicants should have a PhD or equivalent in a relevant subject with the appropriate experience and track record. Preferably, we are looking for an applicant with a strong background on CRISPR, high-throughput technologies and molecular biology. He/she is intended to establish genetic and epigenetic inactivation of genes using CRISPR-Cas9 genome editing, locus-specific epigenetic modifications using dCas9 and CRISPRi in the animal models of pulmonary hypertension. 

About the employer

The Max Planck Institute for Heart and Lung Research in Bad Nauheim is an interdisciplinary research institution with international flair. Our researchers have the opportunity to work on various model systems by making use of the latest cutting-edge technologies.

The Max Planck Society is committed to increase the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, The Max Planck Society strives for gender and diversity equality. We welcome applications from all backgrounds.

Your application

To apply please submit 1) a cover letter briefly summarizing your research interests and career goals, 2) your CV with publications, and 3) a list of 2 references, as PDF or word documents via our applicant portal.

The deadline for applications is 30.11.2020.

Contact

Max Planck Institute for Heart and Lung Research
Department of Lung Development and Remodeling
Parkstr. 1, 61231
Bad Nauheim
Germany

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