Sofja Kovalevskaja Research Group: Publications

Former and current lab members are highlighted in bold:


Patra C, Talukdar S, Novoyatleva T, Velagala SR, Mühlfeld C, Kundu B, Kundu SC, Engel FB: Silk protein fibroin from Antheraea mylitta for cardiac tissue engineering. Biomaterials. 2012; 33:2673-80.


Patra C, Diehl F, Ferrazzi F, van Amerongen MJ, Novoyatleva T, Schaefer L, Mühlfeld C, Jungblut B, Engel FB: Nephronectin regulates via BMP4-HAS2 signaling the differentiation of the atrio-ventricular canal in zebrafish. Development. 2011; 138(20):4499-509.


Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wietelmann A, Harriss J, Ferrazzi F, Böttger T, Harvey RP, Tucker PW, Engel FB: Cardiac deletion of Smyd2 is dispensable for mouse heart development.
PLoS ONE. 2010; 5(3):e9748.


van Amerongen MJ, Diehl F, Novoyatleva T, Patra C, Engel FB: E2F4 is required for cardiomyocyte proliferation. Cardiovasc Res. 2010; 86(1):92-102.


Novoyatleva T, Diehl F, van Amerongen MJ, Patra C, Ferrazzi F, Bellazzi R, Engel FB: TWEAK is a positive regulator of cardiomyocyte proliferation. Cardiovasc Res. 2010; 85(4):681-90.


Simonides WS, Mulcahey MA, Redout EM, Muller A, Zuidwijk MJ, Visser TJ, Wassen FWJS, Crescenzi A, da-Silva WS, Harney J, Engel FB, Obregon MJ, Larsen PR, Bianco AC, Huang SA: Hypoxia-inducible factor induces local thyroid hormone inactivation in hypoxic-ischemic disease.
J Clin Invest. 2008;118(3):975-983.


Engel FB, Hsieh PCH, Lee RT, Keating MT: FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring and rescues function after myocardial infarction. Proc Natl Acad Sci U S A. 2006; 103(42):15546-51. (supporting information)


Tseng AS, Engel FB, Keating MTThe GSK-3 Inhibitor BIO Promotes Proliferation in Mammalian Cardiomyocytes. Chemistry & Biology. 2006; 13(9):957-63. (supplemental data)


Engel FB, Schebesta M, Keating MT: Anillin Localization Defect in Cardiomyocyte Binucleation. J Mol Cell Cardiol, 2006; 41(4):601-612 (Cover, Editorial).


Schebesta M, Lien CL, Engel FB, Keating MT: Transcriptional Profiling of Caudal Fin Regeneration in Zebrafish. Scientific World Journal Development & Embryology. 2006; 1(S1):38-54.


Engel FB, Schebesta M, Duong MT, Lu G, Ren S, Madwed JB, Jiang H, Wang Y, Keating MT: p38 MAP Kinase Inhibition Enables Proliferation of Adult Mammalian Cardiomyocytes. Genes & Dev.2005; 19(10):1175-87. (supplemental research data)


Philippar U, Schratt G, Dieterich C, Muller JM, Galgoczy P, Engel FB, Keating MT, Gertler F, Schule R, Vingron M, Nordheim A: The SRF Target Gene Fhl2 Antagonizes RhoA/MAL-Dependent Activation of SRF. Mol Cell. 2004; 16(6):867-80.


Gresch O, Engel FB, Nesic D, Tran TT, England HM, Hickman ES, Körner I, Gan L, Chen S, Castro-Obregon S, Hammermann R, Wolf J, Müller-Hartmann H, Nix M, Siebenkotten G, Kraus G, Lun K: New non-viral method for gene transfer into primary cells. Methods, 2004; 33(2):151-63.


Engel FB, Hauck L, Boehm M, Nabel EG, Dietz R, von Harsdorf R: P21CIP1 controls proliferating cell nuclear antigen protein level in adult cardiomyocytes. Mol Cell Biol. 2003; 23(2):555-65.


Engel FB, Hauck L, Cardoso MC, Leonhardt H, Dietz R, von Harsdorf R: A mammalian myocardial cell-free system to study cell cycle reentry in terminally differentiated cardiomyocytes. Circ Res. 1999; 85(3):294-301.



Engel FB:
Cardiomyocyte Proliferation: A Platform for Mammalian Cardiac Repair. Cell Cycle. 2005; 4:1360-63.


van Amerongen MJ and Engel FB: Features of cardiomyocyte proliferation and its potential for cardiac regeneration. See van Amerongen MJ 2008 for the pre-peer-reviewed version of the article above, which has been published in final form at  J Cell Mol Med. 2008; 12(6a):2233-44.